Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer M Toyota, H Suzuki, Y Sasaki, R Maruyama, K Imai, Y Shinomura, ... Cancer research 68 (11), 4123-4132, 2008 | 783 | 2008 |
Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer M Nojima, H Suzuki, M Toyota, Y Watanabe, R Maruyama, S Sasaki, ... Oncogene 26 (32), 4699-4713, 2007 | 290 | 2007 |
Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors H Sato, H Suzuki, M Toyota, M Nojima, R Maruyama, S Sasaki, H Takagi, ... Carcinogenesis 28 (12), 2459-2466, 2007 | 282 | 2007 |
Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer K Akino, M Toyota, H Suzuki, T Imai, R Maruyama, M Kusano, ... Cancer science 98 (1), 88-95, 2007 | 246 | 2007 |
Epigenetic inactivation of CHFR in human tumors M Toyota, Y Sasaki, A Satoh, K Ogi, T Kikuchi, H Suzuki, H Mita, N Tanaka, ... Proceedings of the National Academy of Sciences 100 (13), 7818-7823, 2003 | 244 | 2003 |
The p53 family member genes are involved in the Notch signal pathway Y Sasaki, S Ishida, I Morimoto, T Yamashita, T Kojima, C Kihara, T Tanaka, ... Journal of Biological Chemistry 277 (1), 719-724, 2002 | 235 | 2002 |
Aberrant methylation and silencing of the BNIP3 gene in colorectal and gastric cancer M Murai, M Toyota, H Suzuki, A Satoh, Y Sasaki, K Akino, M Ueno, ... Clinical cancer research 11 (3), 1021-1027, 2005 | 218 | 2005 |
Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer A Satoh, M Toyota, F Itoh, Y Sasaki, H Suzuki, K Ogi, T Kikuchi, H Mita, ... Cancer research 63 (24), 8606-8613, 2003 | 202 | 2003 |
Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer H Suzuki, S Takatsuka, H Akashi, E Yamamoto, M Nojima, R Maruyama, ... Cancer research 71 (17), 5646-5658, 2011 | 192 | 2011 |
The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer K Akino, M Toyota, H Suzuki, H Mita, Y Sasaki, M Ohe-Toyota, JPJ Issa, ... Gastroenterology 129 (1), 156-169, 2005 | 183 | 2005 |
Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours M Murai, M Toyota, A Satoh, H Suzuki, K Akino, H Mita, Y Sasaki, T Ishida, ... British journal of cancer 92 (6), 1165-1172, 2005 | 155 | 2005 |
Epigenetic inactivation of class II transactivator (CIITA) is associated with the absence of interferon-γ-induced HLA-DR expression in colorectal and gastric cancer cells A Satoh, M Toyota, H Ikeda, Y Morimoto, K Akino, H Mita, H Suzuki, ... Oncogene 23 (55), 8876-8886, 2004 | 152 | 2004 |
Gene amplification and overexpression of PRDM14 in breast cancers N Nishikawa, M Toyota, H Suzuki, T Honma, T Fujikane, T Ohmura, ... Cancer research 67 (20), 9649-9657, 2007 | 142 | 2007 |
Comparative genome analysis identifies the vitamin D receptor gene as a direct target of p53-mediated transcriptional activation R Maruyama, F Aoki, M Toyota, Y Sasaki, H Akashi, H Mita, H Suzuki, ... Cancer research 66 (9), 4574-4583, 2006 | 141 | 2006 |
DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers A Satoh, M Toyota, F Itoh, T Kikuchi, T Obata, Y Sasaki, H Suzuki, ... British Journal of Cancer 86 (11), 1817-1823, 2002 | 136 | 2002 |
IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype H Suzuki, S Igarashi, M Nojima, R Maruyama, E Yamamoto, M Kai, ... Carcinogenesis 31 (3), 342-349, 2010 | 129 | 2010 |
The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors H Nishimori, Y Sasaki, K Yoshida, H Irifune, H Zembutsu, T Tanaka, ... Oncogene 21 (54), 8302-8309, 2002 | 128 | 2002 |
PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer Y Watanabe, M Toyota, Y Kondo, H Suzuki, T Imai, M Ohe-Toyota, ... Clinical cancer research 13 (16), 4786-4794, 2007 | 119 | 2007 |
Assessment of the quality of DNA from various formalin-fixed paraffin-embedded (FFPE) tissues and the use of this DNA for next-generation sequencing (NGS) with no artifactual … N Einaga, A Yoshida, H Noda, M Suemitsu, Y Nakayama, A Sakurada, ... PloS one 12 (5), e0176280, 2017 | 114 | 2017 |
CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation L Kashima, M Idogawa, H Mita, M Shitashige, T Yamada, K Ogi, H Suzuki, ... Journal of Biological Chemistry 287 (16), 12975-12984, 2012 | 110 | 2012 |