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Eslam Ali Ibrahim
Eslam Ali Ibrahim
Postdoctoral Researcher at UC Irvine
在 uci.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Thieno [2, 3-d] pyrimidine as a promising scaffold in medicinal chemistry: Recent advances
EMH Ali, MS Abdel-Maksoud, CH Oh
Bioorganic & medicinal chemistry 27 (7), 1159-1194, 2019
852019
Pyrazolo [3, 4-d] pyrimidine based scaffold derivatives targeting kinases as anticancer agents
NSM Ismail, EMH Ali, DA Ibrahim, RAT Serya, DA Abou El Ella
Future Journal of Pharmaceutical Sciences 2 (1), 20-30, 2016
592016
Design, synthesis, and biological evaluation of novel imidazole derivatives possessing terminal sulphonamides as potential BRAFV600Eáinhibitors
EMH Ali, MS Abdel-Maksoud, UM Ammar, KI Mersal, KH Yoo, ...
Bioorganic Chemistry 106, 104508, 2021
312021
Design, synthesis, and anticancer activity of imidazo [2, 1-b] oxazole-based RAF kinase inhibitors
MS Abdel-Maksoud, UM Ammar, MI El-Gamal, MMG El-Din, KI Mersal, ...
Bioorganic Chemistry 93, 103349, 2019
262019
Design, synthesis and anti-inflammatory activity of imidazol-5-yl pyridine derivatives as p38α/MAPK14 inhibitor
EMH Ali, MS Abdel-Maksoud, RM Hassan, KI Mersal, UM Ammar, C Se-In, ...
Bioorganic & Medicinal Chemistry 31, 115969, 2021
232021
Discovery of New Imidazo[2,1-b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro and In Vivo Anti-melanoma Activity
MS Abdel-Maksoud, MI El-Gamal, BS Lee, MM Gamal El-Din, HR Jeon, ...
Journal of Medicinal Chemistry 64 (10), 6877-6901, 2021
212021
New horizons in drug discovery of lymphocyte-specific protein tyrosine kinase (Lck) inhibitors: A decade review (2011–2021) focussing on structure–activity relationship (SAR …
A Elkamhawy, EMH Ali, K Lee
Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1572-1600, 2021
212021
Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl) pyrimidine-based derivatives as dual BRAFV600E/p38α inhibitors
EMH Ali, RFA El-Telbany, MS Abdel-Maksoud, UM Ammar, KI Mersal, ...
European Journal of Medicinal Chemistry 215, 113277, 2021
182021
Structural optimization of imidazothiazole derivatives affords a new promising series as B-Raf V600E inhibitors; synthesis, in vitro assay and in silico screening
UM Ammar, MS Abdel-Maksoud, EMH Ali, KI Mersal, KH Yoo, CH Oh
Bioorganic Chemistry 100, 103967, 2020
172020
Modification of imidazothiazole derivatives gives promising activity in B-Raf kinase enzyme inhibition; synthesis, in vitro studies and molecular docking
UM Ammar, MS Abdel-Maksoud, KI Mersal, EMH Ali, KH Yoo, HS Choi, ...
Bioorganic & Medicinal Chemistry Letters 30 (20), 127478, 2020
122020
Design and synthesis of novel pyrrolo [2, 3-b] pyridine derivatives targeting V600EBRAF
MS Abdel-Maksoud, EMH Ali, UM Ammar, KI Mersal, KH Yoo, CH Oh
Bioorganic & Medicinal Chemistry 28 (11), 115493, 2020
122020
Structural optimization of 4-(imidazol-5-yl) pyridine derivatives affords broad-spectrum anticancer agents with selective B-RAFV600E/p38α kinase inhibitory activity: synthesis …
EMH Ali, KI Mersal, UM Ammar, SO Zaraei, MS Abdel-Maksoud, ...
European Journal of Pharmaceutical Sciences 171, 106115, 2022
92022
Ligand-based design, molecular dynamics and ADMET studies of suggested SARS-CoV-2 M pro inhibitors
NM Mohamed, EMH Ali, AM AboulMagd
RSC advances 11 (8), 4523-4538, 2021
92021
Identification of novel aryl carboxamide derivatives as death-associated protein kinase 1 (DAPK1) inhibitors with anti-proliferative activities: design, synthesis, in vitro …
A Elkamhawy, S Paik, EMH Ali, AHE Hassan, SJ Kang, K Lee, EJ Roh
Pharmaceuticals 15 (9), 1050, 2022
72022
How do coffee substitutes compare to coffee? A comprehensive review of its quality characteristics, sensory characters, phytochemicals, health benefits and safety. Food Biosci …
MM Mostafa, E Ali, M Gamal, MA Farag
62021
Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells
KI Mersal, MS Abdel-Maksoud, EMH Ali, UM Ammar, SO Zaraei, ...
European Journal of Medicinal Chemistry 261, 115779, 2023
22023
Design, synthesis, in vitro determination and molecular docking studies of 4-(1-(tert-butyl)-3-phenyl-1H-pyrazol-4-yl) pyridine derivatives with terminal sulfonamide …
KI Mersal, MS Abdel-Maksoud, EMH Ali, UM Ammar, SO Zaraei, JM Kim, ...
Medicinal Chemistry Research 30 (10), 1925-1942, 2021
22021
ByeTAC: Bypassing an E3 Ligase for Targeted Protein Degradation
EMH Ali, C Loy, DJ Trader
bioRxiv, 2024.01. 20.576376, 2024
12024
Discovery of a non-covalent ligand for Rpn-13, a therapeutic target for hematological cancers
CA Loy, CS Muli, EMH Ali, D Xie, MH Ahmed, CB Post, DJ Trader
Bioorganic & Medicinal Chemistry Letters 95, 129485, 2023
12023
Discovery of potential RAF-selective back pocket as a promising biological target for BRAF inhibitors in the treatment of resistant melanoma: Design, synthesis, biological …
U Ammar, M Gamal, M Abdel-Maksoud, E Ali, Z Mahmoud, K Deug, P Jun, ...
Cancer Research 84 (6_Supplement), 2024
2024
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