| The neuronal channel NALCN contributes resting sodium permeability and is required for normal respiratory rhythm B Lu, Y Su, S Das, J Liu, J Xia, D Ren Cell 129 (2), 371-383, 2007 | 369 | 2007 |
| Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds Z Li, C Wang, Z Wang, C Zhu, J Li, T Sha, L Ma, C Gao, YI Yang, Y Sun, ... Nature 575 (7781), 203-209, 2019 | 367 | 2019 |
| Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex B Lu, Q Zhang, H Wang, Y Wang, M Nakayama, D Ren Neuron 68 (3), 488-499, 2010 | 216 | 2010 |
| Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80 B Lu, Y Su, S Das, H Wang, Y Wang, J Liu, D Ren Nature 457 (7230), 741-744, 2009 | 168 | 2009 |
| Emerging new concepts of degrader technologies Y Ding, Y Fei, B Lu Trends in Pharmacological Sciences 41 (7), 464-474, 2020 | 142 | 2020 |
| ATTEC: a potential new approach to target proteinopathies Z Li, C Zhu, Y Ding, Y Fei, B Lu Autophagy 16 (1), 185-187, 2020 | 125 | 2020 |
| Identification of NUB1 as a suppressor of mutant Huntingtin toxicity via enhanced protein clearance B Lu, I Al-Ramahi, A Valencia, Q Wang, F Berenshteyn, H Yang, ... Nature neuroscience 16 (5), 562-570, 2013 | 107 | 2013 |
| Degradation of lipid droplets by chimeric autophagy-tethering compounds Y Fu, N Chen, Z Wang, S Luo, Y Ding, B Lu Cell research 31 (9), 965-979, 2021 | 105 | 2021 |
| A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology J Wie, Z Liu, H Song, TF Tropea, L Yang, H Wang, Y Liang, C Cang, ... Nature 591 (7850), 431-437, 2021 | 93 | 2021 |
| A novel human embryonic stem cell-derived Huntington's disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT-dependent neurodegeneration B Lu, J Palacino The FASEB Journal, 2013 | 93 | 2013 |
| A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity Y Yao, X Cui, I Al-Ramahi, X Sun, B Li, J Hou, M Difiglia, J Palacino, ... Elife 4, e05449, 2015 | 77 | 2015 |
| Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response Y Yang, TL Willis, RW Button, CJ Strang, Y Fu, X Wen, PRC Grayson, ... Nature communications 10 (1), 3759, 2019 | 76 | 2019 |
| A toxic mutant huntingtin species is resistant to selective autophagy Y Fu, P Wu, Y Pan, X Sun, H Yang, M Difiglia, B Lu Nature chemical biology 13 (11), 1152-1154, 2017 | 53 | 2017 |
| Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models M Yu, Y Fu, Y Liang, H Song, Y Yao, P Wu, Y Yao, Y Pan, X Wen, L Ma, ... Cell Research 27 (12), 1441-1465, 2017 | 47 | 2017 |
| Emerging degrader technologies engaging lysosomal pathways Y Ding, D Xing, Y Fei, B Lu Chemical Society Reviews 51 (21), 8832-8876, 2022 | 45 | 2022 |
| Targeting Gpr52 lowers mutant HTT levels and rescues Huntington’s disease-associated phenotypes H Song, H Li, S Guo, Y Pan, Y Fu, Z Zhou, Z Li, X Wen, X Sun, B He, H Gu, ... Brain 141 (6), 1782-1798, 2018 | 39 | 2018 |
| Lowering mutant huntingtin levels and toxicity: Autophagy-Endolysosome pathways in Huntington's disease E Valionyte, Y Yang, SL Roberts, J Kelly, B Lu, S Luo Journal of molecular biology 432 (8), 2673-2691, 2020 | 36 | 2020 |
| TR-FRET assays of Huntingtin protein fragments reveal temperature and polyQ length-dependent conformational changes X Cui, Q Liang, Y Liang, M Lu, Y Ding, B Lu Scientific reports 4 (1), 5601, 2014 | 36 | 2014 |
| High-throughput functional analysis distinguishes pathogenic, nonpathogenic, and compensatory transcriptional changes in neurodegeneration I Al-Ramahi, B Lu, S Di Paola, K Pang, M de Haro, I Peluso, ... Cell systems 7 (1), 28-40. e4, 2018 | 31 | 2018 |
| Conformation polymorphism of polyglutamine proteins X Feng, S Luo, B Lu Trends in biochemical sciences 43 (6), 424-435, 2018 | 31 | 2018 |
