IN SILICO METHODS FOR DRUG DESIGN AND DISCOVERY S Brogi, TC Ramalho, JL Medina-Franco, K Kuca, M Valko | 205 | 2020 |
Multitarget compounds bearing tacrine-and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease L Ismaili, B Refouvelet, M Benchekroun, S Brogi, M Brindisi, S Gemma, ... Progress in neurobiology 151, 4-34, 2017 | 183 | 2017 |
Improving curcumin bioavailability: Current strategies and future perspectives R Tabanelli, S Brogi, V Calderone Pharmaceutics 13 (10), 1715, 2021 | 120 | 2021 |
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases S Maramai, S Gemma, S Brogi, G Campiani, S Butini, H Stark, M Brindisi Frontiers in neuroscience 10, 222411, 2016 | 96 | 2016 |
Old but gold: tracking the new guise of histone deacetylase 6 (HDAC6) enzyme as a biomarker and therapeutic target in rare diseases M Brindisi, AP Saraswati, S Brogi, S Gemma, S Butini, G Campiani Journal of medicinal chemistry 63 (1), 23-39, 2020 | 90 | 2020 |
Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation MY Wu, G Esteban, S Brogi, M Shionoya, L Wang, G Campiani, M Unzeta, ... European Journal of Medicinal Chemistry 121, 864-879, 2016 | 90 | 2016 |
Role of hydrogen sulfide in endothelial dysfunction: Pathophysiology and therapeutic approaches V Citi, A Martelli, E Gorica, S Brogi, L Testai, V Calderone Journal of advanced research 27, 99-113, 2021 | 80 | 2021 |
Anti‐inflammatory and antiviral roles of hydrogen sulfide: Rationale for considering H2S donors in COVID‐19 therapy V Citi, A Martelli, V Brancaleone, S Brogi, G Gojon, R Montanaro, ... British journal of pharmacology 177 (21), 4931-4941, 2020 | 80 | 2020 |
Development and pharmacological characterization of selective blockers of 2-arachidonoyl glycerol degradation with efficacy in rodent models of multiple sclerosis and pain M Brindisi, S Maramai, S Gemma, S Brogi, A Grillo, L Di Cesare Mannelli, ... Journal of medicinal chemistry 59 (6), 2612-2632, 2016 | 80 | 2016 |
Polypharmacology of dopamine receptor ligands S Butini, K Nikolic, S Kassel, H Brückmann, S Filipic, D Agbaba, S Gemma, ... Progress in neurobiology 142, 68-103, 2016 | 78 | 2016 |
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking M Brindisi, S Brogi, N Relitti, A Vallone, S Butini, S Gemma, E Novellino, ... Scientific reports 5 (1), 9705, 2015 | 75 | 2015 |
Mimicking the intramolecular hydrogen bond: synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents S Gemma, C Camodeca, M Brindisi, S Brogi, G Kukreja, S Kunjir, ... Journal of medicinal chemistry 55 (23), 10387-10404, 2012 | 72 | 2012 |
The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing‐Dependent Dysfunction: Potential Role of SIRT1 L Testai, E Piragine, I Piano, L Flori, E Da Pozzo, V Miragliotta, A Pirone, ... Oxidative Medicine and Cellular Longevity 2020 (1), 4650207, 2020 | 64 | 2020 |
Discovery and cardioprotective effects of the first non-Peptide agonists of the G protein-coupled prokineticin receptor-1 A Gasser, S Brogi, K Urayama, T Nishi, H Kurose, A Tafi, N Ribeiro, ... PloS one 10 (4), e0121027, 2015 | 62 | 2015 |
Computational Tool for Fast in silico Evaluation of hERG K+ Channel Affinity G Chemi, S Gemma, G Campiani, S Brogi, S Butini, M Brindisi Frontiers in chemistry 5, 7, 2017 | 61 | 2017 |
Disease‐Modifying Anti‐Alzheimer's Drugs: Inhibitors of Human Cholinesterases Interfering with β‐Amyloid Aggregation S Brogi, S Butini, S Maramai, R Colombo, L Verga, C Lanni, E De Lorenzi, ... CNS neuroscience & therapeutics 20 (7), 624-632, 2014 | 57 | 2014 |
Organic isothiocyanates as hydrogen sulfide donors A Martelli, V Citi, L Testai, S Brogi, V Calderone Antioxidants & Redox Signaling 32 (2), 110-144, 2020 | 56 | 2020 |
Verbascoside Inhibits Promastigote Growth and Arginase Activity of Leishmania amazonensis CC Maquiaveli, JF Lucon-Junior, S Brogi, G Campiani, S Gemma, ... Journal of natural products 79 (5), 1459-1463, 2016 | 52 | 2016 |
Discovery of GPCR ligands for probing signal transduction pathways S Brogi, A Tafi, L Désaubry, CG Nebigil Frontiers in pharmacology 5, 119795, 2014 | 52 | 2014 |
Targeting Dopamine D3 and Serotonin 5-HT1A and 5-HT2A Receptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and … M Brindisi, S Butini, S Franceschini, S Brogi, F Trotta, S Ros, A Cagnotto, ... Journal of medicinal chemistry 57 (22), 9578-9597, 2014 | 52 | 2014 |