| Lost in transcription: p21 repression, mechanisms, and consequences AL Gartel, SK Radhakrishnan Cancer research 65 (10), 3980-3985, 2005 | 1066 | 2005 |
| Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells SK Radhakrishnan, CS Lee, P Young, A Beskow, JY Chan, RJ Deshaies Molecular cell 38 (1), 17-28, 2010 | 529 | 2010 |
| Identification of a chemical inhibitor of the oncogenic transcription factor forkhead box M1 SK Radhakrishnan, UG Bhat, DE Hughes, IC Wang, RH Costa, AL Gartel Cancer research 66 (19), 9731-9735, 2006 | 264 | 2006 |
| p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition SK Radhakrishnan, W den Besten, RJ Deshaies Elife 3, e01856, 2014 | 230 | 2014 |
| Inhibition of NGLY1 inactivates the transcription factor Nrf1 and potentiates proteasome inhibitor cytotoxicity FM Tomlin, UIM Gerling-Driessen, YC Liu, RA Flynn, JR Vangala, ... ACS central science 3 (11), 1143-1155, 2017 | 180 | 2017 |
| Pro-apoptotic role of NF-κB: implications for cancer therapy SK Radhakrishnan, S Kamalakaran Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1766 (1), 53-62, 2006 | 155 | 2006 |
| Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle SK Radhakrishnan, CS Feliciano, F Najmabadi, A Haegebarth, ... Oncogene 23 (23), 4173-4176, 2004 | 146 | 2004 |
| RNA interference as a new strategy against viral hepatitis SK Radhakrishnan, TJ Layden, AL Gartel Virology 323 (2), 173-181, 2004 | 101 | 2004 |
| Identification of estrogen-responsive genes using a genome-wide analysis of promoter elements for transcription factor binding sites S Kamalakaran, SK Radhakrishnan, WT Beck Journal of Biological Chemistry 280 (22), 21491-21497, 2005 | 74 | 2005 |
| CDK9 phosphorylates p53 on serine residues 33, 315 and 392 SK Radhakrishnan, AL Gartel Cell cycle 5 (5), 519-521, 2006 | 73 | 2006 |
| A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity SK Radhakrishnan, AL Gartel Cancer research 66 (6), 3264-3270, 2006 | 66 | 2006 |
| Multiple alternate p21 transcripts are regulated by p53 in human cells SK Radhakrishnan, J Gierut, AL Gartel Oncogene 25 (12), 1812-1815, 2006 | 62 | 2006 |
| FOXM1: the Achilles' heel of cancer? SK Radhakrishnan, AL Gartel Nature Reviews Cancer 8 (3), 242-242, 2008 | 51 | 2008 |
| Nrf1 can be processed and activated in a proteasome-independent manner JR Vangala, F Sotzny, E Krüger, RJ Deshaies, SK Radhakrishnan Current Biology 26 (18), R834-R835, 2016 | 40 | 2016 |
| The PPAR-? Agonist Pioglitazone Post-Trancriptionally Induces p21 in PC3 Prostate Cancer but Not in Other Cell Lines SK Radhakrishnan, AL Gartel Cell Cycle 4 (4), 575-577, 2005 | 38 | 2005 |
| Disabling the protease DDI2 attenuates the transcriptional activity of NRF1 and potentiates proteasome inhibitor cytotoxicity A Northrop, JR Vangala, A Feygin, SK Radhakrishnan International journal of molecular sciences 21 (1), 327, 2020 | 33 | 2020 |
| Liver-specific deletion of Ngly1 causes abnormal nuclear morphology and lipid metabolism under food stress H Fujihira, Y Masahara-Negishi, Y Akimoto, H Hirayama, HC Lee, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (3), 165588, 2020 | 27 | 2020 |
| Nrf1-mediated transcriptional regulation of the proteasome requires a functional TIP60 complex JR Vangala, SK Radhakrishnan Journal of Biological Chemistry 294 (6), 2036-2045, 2019 | 24 | 2019 |
| A novel anticancer agent ARC antagonizes HIV-1 and HCV S Nekhai, UG Bhat, T Ammosova, SK Radhakrishnan, M Jerebtsova, ... Oncogene 26 (26), 3899-3903, 2007 | 24 | 2007 |
| Regulation of NRF1, a master transcription factor of proteasome genes: Implications for cancer and neurodegeneration A Northrop, HA Byers, SK Radhakrishnan Molecular Biology of the Cell 31 (20), 2158-2163, 2020 | 23 | 2020 |
