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Vangala Janakiram Reddy
Vangala Janakiram Reddy
Research Scientist, Department of Pathology, Virginia Commonwealth University
在 vcuhealth.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
Inhibition of NGLY1 inactivates the transcription factor Nrf1 and potentiates proteasome inhibitor cytotoxicity
FM Tomlin, UIM Gerling-Driessen, YC Liu, RA Flynn, JR Vangala, ...
ACS central science 3 (11), 1143-1155, 2017
1882017
Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents
MA Reddy, N Jain, D Yada, C Kishore, JR Vangala, R P. Surendra, ...
Journal of medicinal chemistry 54 (19), 6751-6760, 2011
962011
Regulation of PSMB5 protein and β subunits of mammalian proteasome by constitutively activated signal transducer and activator of transcription 3 (STAT3): potential role in …
JR Vangala, S Dudem, N Jain, SV Kalivendi
Journal of Biological Chemistry 289 (18), 12612-12622, 2014
742014
Nrf1 can be processed and activated in a proteasome-independent manner
JR Vangala, F Sotzny, E Krüger, RJ Deshaies, SK Radhakrishnan
Current Biology 26 (18), R834-R835, 2016
432016
Disabling the protease DDI2 attenuates the transcriptional activity of NRF1 and potentiates proteasome inhibitor cytotoxicity
A Northrop, JR Vangala, A Feygin, SK Radhakrishnan
International journal of molecular sciences 21 (1), 327, 2020
362020
Stereoselective total synthesis of (+)-oploxyne A,(−)-oploxyne B, and their C-10 epimers and structure revision of natural oploxyne B
JS Yadav, K Boyapelly, SR Alugubelli, S Pabbaraja, JR Vangala, ...
The Journal of Organic Chemistry 76 (8), 2568-2576, 2011
312011
Nrf1-mediated transcriptional regulation of the proteasome requires a functional TIP60 complex
JR Vangala, SK Radhakrishnan
Journal of Biological Chemistry 294 (6), 2036-2045, 2019
262019
Two new sesquiterpenoids from the rhizomes of Nardostachys jatamansi
K Rekha, RR Rao, R Pandey, KR Prasad, KS Babu, JR Vangala, ...
Journal of Asian natural products research 15 (2), 111-116, 2013
252013
BET inhibitors synergize with carfilzomib to induce cell death in cancer cells via impairing Nrf1 transcriptional activity and exacerbating the unfolded protein response
JR Vangala, A Potluri, SK Radhakrishnan
Biomolecules 10 (4), 501, 2020
192020
Inhibition of NGLY1 inactivates the transcription factor Nrf1 and potentiates proteasome inhibitor cytotoxicity. ACS Cent Sci 3: 1143–1155
FM Tomlin, UIM Gerling-Driessen, YC Liu, RA Flynn, JR Vangala, ...
PLoS Genet 13, e1006696, 2017
92017
Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity. ACS Central Science, 3 (11), 1143–1155
FM Tomlin, UIM Gerling-Driessen, YC Liu, RA Flynn, JR Vangala, ...
52017
Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy
MA Ward, JR Vangala, HE Kamber Kaya, HA Byers, N Hosseini, A Diaz, ...
Journal of Cell Biology 223 (6), e202306150, 2024
32024
Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer
HA Byers, AN Brooks, JR Vangala, JM Grible, A Feygin, CV Clevenger, ...
Scientific Reports 13 (1), 15843, 2023
32023
R, PS; Addlagatta, A.; Kalivendi, SV; Sreedhar, B. Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents
MA Reddy, N Jain, D Yada, C Kishore, JR Vangala
J. Med. Chem 54 (19), 6751-6760, 2011
32011
Regulation of PSMB5 and β-subunits of mammalian proteasome by constitutively activated STAT3: potential role in Bortezomib mediated anticancer therapy
GR Vangala, S Dudem, N Jain, SD Kaliventi
J Biol Chem 113, 542829, 2014
22014
Inhibition of NGLY1 inactivates the transcription factor Nrf1 and potentiates proteasome inhibitor cytotoxicity
C Bertozzi, F Tomlin, U Gerling-Driessen, YC Liu, R Flynn, J Vangala, ...
12017
Abstract 1541 Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy
S Radhakrishnan, M Ward, J Vangala, HEK Kaya
Journal of Biological Chemistry 300 (3), 2024
2024
Transcriptional Regulation of the Proteasome: Implications for Cancer Therapy
S Radhakrishnan, J Vangala
The FASEB Journal 34 (S1), 1-1, 2020
2020
Proteotoxic stress-induced Nrf1 transcriptional program requires a functional TIP60 complex
JR Vangala, SK Radhakrishnan
bioRxiv, 443937, 2018
2018
Role of STATS in the regulation of Mammalian Proteasome: Implications for cancer and proteasome associated disorders
VJ Reddy
2014
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