| Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: antagonism in brain and potentiation in spinal cord of the rat JH Tian, W Xu, Y Fang, JS Mogil, JE Grisel, DK Grandy, JS Han British journal of pharmacology 120 (4), 676, 1997 | 276 | 1997 |
| Serotonin receptor subtypes in spinal antinociception in the rat. W Xu, XC Qiu, JS Han Journal of Pharmacology and Experimental Therapeutics 269 (3), 1182-1189, 1994 | 135 | 1994 |
| The endocannabinoid system as a target for alkamides from Echinacea angustifolia roots K Woelkart, W Xu, Y Pei, A Makriyannis, RP Picone, R Bauer Planta Medica 71 (08), 701-705, 2005 | 123 | 2005 |
| Mephedrone (‘bath salt’) elicits conditioned place preference and dopamine-sensitive motor activation R Lisek, W Xu, E Yuvasheva, YT Chiu, AB Reitz, LY Liu-Chen, SM Rawls Drug and alcohol dependence 126 (1-2), 257-262, 2012 | 114 | 2012 |
| (-)-7′-Isothiocyanato-11-hydroxy-1′, 1′-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six … RP Picone, AD Khanolkar, W Xu, LA Ayotte, GA Thakur, DP Hurst, ... Molecular pharmacology 68 (6), 1623-1635, 2005 | 111 | 2005 |
| Localization of the κ opioid receptor in lipid rafts W Xu, SI Yoon, P Huang, Y Wang, C Chen, PLG Chong, LY Liu-Chen Journal of Pharmacology and Experimental Therapeutics 317 (3), 1295-1306, 2006 | 101 | 2006 |
| Endogenous orphanin FQ: evidence for a role in the modulation of electroacupuncture analgesia and the development of tolerance to analgesia produced by morphine and … JH Tian, W Zhang, Y Fang, W Xu, DK Grandy, JS Han British journal of pharmacology 124 (1), 21-26, 1998 | 101 | 1998 |
| Cholesterol reduction by methyl-β-cyclodextrin attenuates the delta opioid receptor-mediated signaling in neuronal cells but enhances it in non-neuronal cells P Huang, W Xu, SI Yoon, C Chen, PLG Chong, LY Liu-Chen Biochemical pharmacology 73 (4), 534-549, 2007 | 93 | 2007 |
| Synthesis and in vitro evaluation of salvinorin A analogues: effect of configuration at C (2) and substitution at C (18) C Béguin, MR Richards, JG Li, Y Wang, W Xu, LY Liu-Chen, ... Bioorganic & medicinal chemistry letters 16 (17), 4679-4685, 2006 | 81 | 2006 |
| Isoquinoline Alkaloids Isolated from Corydalis yanhusuo and Their Binding Affinities at the Dopamine D1 Receptor ZZ Ma, W Xu, NH Jensen, BL Roth, LY Liu-Chen, DYW Lee Molecules 13 (9), 2303-2312, 2008 | 77 | 2008 |
| Standard protecting groups create potent and selective κ opioids: Salvinorin B alkoxymethyl ethers TA Munro, KK Duncan, W Xu, Y Wang, LY Liu-Chen, WA Carlezon Jr, ... Bioorganic & medicinal chemistry 16 (3), 1279-1286, 2008 | 75 | 2008 |
| 2-Methoxymethyl-salvinorin B is a potent κ opioid receptor agonist with longer lasting action in vivo than salvinorin A Y Wang, Y Chen, W Xu, DYW Lee, Z Ma, SM Rawls, A Cowan, ... Journal of Pharmacology and Experimental Therapeutics 324 (3), 1073-1083, 2008 | 68 | 2008 |
| Pharmacophoric requirements for the cannabinoid side chain. Probing the cannabinoid receptor subsite at C1 ‘ DP Papahatjis, SP Nikas, T Kourouli, R Chari, W Xu, RG Pertwee, ... Journal of medicinal chemistry 46 (15), 3221-3229, 2003 | 67 | 2003 |
| Functional role of the spatial proximity of Asp114 (2.50) in TMH 2 and Asn332 (7.49) in TMH 7 of the μ opioid receptor W Xu, F Ozdener, JG Li, C Chen, JK de Riel, H Weinstein, LY Liu-Chen FEBS letters 447 (2-3), 318-324, 1999 | 59 | 1999 |
| N-methylacetamide analog of salvinorin A: A highly potent and selective κ-opioid receptor agonist with oral efficacy C Beguin, DN Potter, JA DiNieri, TA Munro, MR Richards, TA Paine, ... Journal of Pharmacology and Experimental Therapeutics 324 (1), 188-195, 2008 | 56 | 2008 |
| High affinity electrophilic and photoactivatable covalent endocannabinoid probes for the CB1 receptor C Li, W Xu, SK Vadivel, P Fan, A Makriyannis Journal of medicinal chemistry 48 (20), 6423-6429, 2005 | 56 | 2005 |
| L-isocorypalmine reduces behavioral sensitization and rewarding effects of cocaine in mice by acting on dopamine receptors W Xu, Y Wang, Z Ma, YT Chiu, P Huang, K Rasakham, E Unterwald, ... Drug and alcohol dependence 133 (2), 693-703, 2013 | 51 | 2013 |
| Palmitoylation of the rat μ opioid receptor C Chen, V Shahabi, W Xu, LY Liu-Chen FEBS letters 441 (1), 148-152, 1998 | 50 | 1998 |
| Agonist treatment did not affect association of mu opioid receptors with lipid rafts and cholesterol reduction had opposite effects on the receptor-mediated signaling in rat … P Huang, W Xu, SI Yoon, C Chen, PLG Chong, EM Unterwald, ... Brain research 1184, 46-56, 2007 | 43 | 2007 |
| The conserved cysteine 7.38 residue is differentially accessible in the binding-site crevices of the μ, δ, and κ opioid receptors W Xu, C Chen, P Huang, J Li, JK de Riel, JA Javitch, LY Liu-Chen Biochemistry 39 (45), 13904-13915, 2000 | 41 | 2000 |
