CD2-associated protein directly interacts with the actin cytoskeleton S Lehtonen, F Zhao, E Lehtonen American Journal of Physiology-Renal Physiology 283 (4), F734-F743, 2002 | 245 | 2002 |
Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and α-actinin are components of the nephrin multiprotein complex S Lehtonen, JJ Ryan, K Kudlicka, N Iino, H Zhou, MG Farquhar Proceedings of the National Academy of Sciences 102 (28), 9814-9819, 2005 | 215 | 2005 |
Nephrin TRAP mice lack slit diaphragms and show fibrotic glomeruli and cystic tubular lesions M Rantanen, T Palmén, A Pätäri, H Ahola, S Lehtonen, A Eva, T Floss, ... Journal of the American Society of Nephrology 13 (6), 1586-1594, 2002 | 148 | 2002 |
The R-Ras interaction partner ORP3 regulates cell adhesion M Lehto, MI Mäyränpää, T Pellinen, P Ihalmo, S Lehtonen, ... Journal of cell science 121 (5), 695-705, 2008 | 125 | 2008 |
In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2 S Lehtonen, A Ora, VM Olkkonen, L Geng, M Zerial, S Somlo, E Lehtonen Journal of Biological Chemistry 275 (42), 32888-32893, 2000 | 124 | 2000 |
Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrin S Lehtonen, E Lehtonen, K Kudlicka, H Holthöfer, MG Farquhar The American journal of pathology 165 (3), 923-936, 2004 | 108 | 2004 |
Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia J Saarikangas, PK Mattila, M Varjosalo, M Bovellan, J Hakanen, ... Journal of cell science 124 (8), 1245-1255, 2011 | 98 | 2011 |
ORP2, a homolog of oxysterol binding protein, regulates cellular cholesterol metabolism S Laitinen, M Lehto, S Lehtonen, K Hyvärinen, S Heino, E Lehtonen, ... Journal of lipid research 43 (2), 245-255, 2002 | 92 | 2002 |
Metformin increases glucose uptake and acts renoprotectively by reducing SHIP2 activity Z Polianskyte-Prause, TA Tolvanen, S Lindfors, V Dumont, M Van, ... The FASEB Journal 33 (2), 2858, 2019 | 87 | 2019 |
Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking AA Wasik, Z Polianskyte-Prause, MQ Dong, AS Shaw, JR Yates III, ... Molecular biology of the cell 23 (17), 3370-3379, 2012 | 78 | 2012 |
β-Catenin mediates adriamycin-induced albuminuria and podocyte injury in adult mouse kidneys E Heikkilä, J Juhila, M Lassila, M Messing, N Perälä, E Lehtonen, ... Nephrology Dialysis Transplantation 25 (8), 2437-2446, 2010 | 78 | 2010 |
Interaction of endogenous nephrin and CD2-associated protein in mouse epithelial M-1 cell line T Palme, S Lehtonen, A Ora, D Kerjaschki, C Antignac, E Lehtonen, ... Journal of the American Society of Nephrology 13 (7), 1766-1772, 2002 | 77 | 2002 |
Subfamily III of mammalian oxysterol-binding protein (OSBP) homologues: the expression and intracellular localization of ORP3, ORP6, and ORP7 M Lehto, J Tienari, S Lehtonen, E Lehtonen, VM Olkkonen Cell and tissue research 315 (1), 39-57, 2004 | 75 | 2004 |
Predictive role of Toll-like receptors 2, 4, and 9 in oral tongue squamous cell carcinoma LK Mäkinen, T Atula, V Häyry, L Jouhi, N Datta, S Lehtonen, A Ahmed, ... Oral oncology 51 (1), 96-102, 2015 | 65 | 2015 |
Lipid phosphatase SHIP2 downregulates insulin signalling in podocytes ME Hyvönen, P Saurus, A Wasik, E Heikkilä, M Havana, R Trokovic, ... Molecular and cellular endocrinology 328 (1-2), 70-79, 2010 | 62 | 2010 |
Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway P Saurus, S Kuusela, E Lehtonen, ME Hyvönen, M Ristola, CL Fogarty, ... Cell death & disease 6 (5), e1752-e1752, 2015 | 57 | 2015 |
Functions of the podocyte proteins nephrin and Neph3 and the transcriptional regulation of their genes M Ristola, S Lehtonen Clinical Science 126 (5), 315-328, 2014 | 45 | 2014 |
The endocytic adaptor protein ARH associates with motor and centrosomal proteins and is involved in centrosome assembly and cytokinesis S Lehtonen, M Shah, R Nielsen, N Iino, JJ Ryan, H Zhou, MG Farquhar Molecular biology of the cell 19 (7), 2949-2961, 2008 | 44 | 2008 |
PACSIN2 accelerates nephrin trafficking and is up-regulated in diabetic kidney disease V Dumont, TA Tolvanen, S Kuusela, H Wang, TA Nyman, S Lindfors, ... The FASEB Journal 31 (9), 3978, 2017 | 43 | 2017 |
Glucose transporters in diabetic kidney disease—friends or foes? AA Wasik, S Lehtonen Frontiers in Endocrinology 9, 155, 2018 | 42 | 2018 |