| KIAA1429 acts as an oncogenic factor in breast cancer by regulating CDK1 in an N6-methyladenosine-independent manner JY Qian, J Gao, X Sun, MD Cao, L Shi, TS Xia, WB Zhou, S Wang, Q Ding, ... Oncogene 38 (33), 6123-6141, 2019 | 181 | 2019 |
| Inhibition of AIM2 inflammasome-mediated pyroptosis by Andrographolide contributes to amelioration of radiation-induced lung inflammation and fibrosis J Gao, S Peng, X Shan, G Deng, L Shen, J Sun, C Jiang, X Yang, ... Cell death & disease 10 (12), 957, 2019 | 139 | 2019 |
| Exosomal transfer of cisplatin-induced miR-425-3p confers cisplatin resistance in NSCLC through activating autophagy Y Ma, D Yuwen, J Chen, B Zheng, J Gao, M Fan, W Xue, Y Wang, W Li, ... International Journal of Nanomedicine, 8121-8132, 2019 | 102 | 2019 |
| Prognostic role of circulating exosomal miR-425-3p for the response of NSCLC to platinum-based chemotherapy D Yuwen, Y Ma, D Wang, J Gao, X Li, W Xue, M Fan, Q Xu, Y Shen, Y Shu Cancer Epidemiology, Biomarkers & Prevention 28 (1), 163-173, 2019 | 99 | 2019 |
| Activating AMPK to restore tight junction assembly in intestinal epithelium and to attenuate experimental colitis by metformin L Chen, J Wang, Q You, S He, Q Meng, J Gao, X Wu, Y Shen, Y Sun, ... Frontiers in pharmacology 9, 761, 2018 | 93 | 2018 |
| Annexin A5 regulates hepatic macrophage polarization via directly targeting PKM2 and ameliorates NASH F Xu, M Guo, W Huang, L Feng, J Zhu, K Luo, J Gao, B Zheng, LD Kong, ... Redox biology 36, 101634, 2020 | 89 | 2020 |
| Andrographolide reversed 5-FU resistance in human colorectal cancer by elevating BAX expression W Wang, W Guo, L Li, Z Fu, W Liu, J Gao, Y Shu, Q Xu, Y Sun, Y Gu Biochemical pharmacology 121, 8-17, 2016 | 86 | 2016 |
| The antioxidant procyanidin reduces reactive oxygen species signaling in macrophages and ameliorates experimental colitis in mice L Chen, Q You, L Hu, J Gao, Q Meng, W Liu, X Wu, Q Xu Frontiers in Immunology 8, 1910, 2018 | 84 | 2018 |
| Andrographolide alleviates Parkinsonism in MPTP‐PD mice via targeting mitochondrial fission mediated by dynamin‐related protein 1 J Geng, W Liu, J Gao, C Jiang, T Fan, Y Sun, ZH Qin, Q Xu, W Guo, J Gao British journal of pharmacology 176 (23), 4574-4591, 2019 | 80 | 2019 |
| Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation S Peng, J Gao, W Liu, C Jiang, X Yang, Y Sun, W Guo, Q Xu Oncotarget 7 (49), 80262, 2016 | 76 | 2016 |
| Inhibition of autophagy by andrographolide resensitizes cisplatin-resistant non-small cell lung carcinoma cells via activation of the Akt/mTOR pathway S Mi, G Xiang, D Yuwen, J Gao, W Guo, X Wu, X Wu, Y Sun, Y Su, Y Shen, ... Toxicology and Applied Pharmacology 310, 78-86, 2016 | 44 | 2016 |
| Decrease of functional activated T and B cells and treatment of glomerulonephitis in lupus-prone mice using a natural flavonoid astilbin L Guo, W Liu, T Lu, W Guo, J Gao, Q Luo, X Wu, Y Sun, X Wu, Y Shen, ... PLoS One 10 (4), e0124002, 2015 | 39 | 2015 |
| Allosteric inhibition reveals SHP2-mediated tumor immunosuppression in colon cancer by single-cell transcriptomics J Gao, Z Wu, M Zhao, R Zhang, M Li, D Sun, H Cheng, X Qi, Y Shen, Q Xu, ... Acta Pharmaceutica Sinica B 12 (1), 149-166, 2022 | 36 | 2022 |
| Allosteric inhibition of SHP2 uncovers aberrant TLR7 trafficking in aggravating psoriasis Y Zhu, Z Wu, W Yan, F Shao, B Ke, X Jiang, J Gao, W Guo, Y Lai, H Ma, ... EMBO Molecular Medicine 14 (3), e14455, 2022 | 34 | 2022 |
| Design, Synthesis, and Evaluation of o-(Biphenyl-3-ylmethoxy)nitrophenyl Derivatives as PD-1/PD-L1 Inhibitors with Potent Anticancer Efficacy In Vivo Y OuYang, J Gao, L Zhao, J Lu, H Zhong, H Tang, S Jin, L Yue, Y Li, ... Journal of Medicinal Chemistry 64 (11), 7646-7666, 2021 | 33 | 2021 |
| Triggering a switch from basal-to luminal-like breast cancer subtype by the small-molecule diptoindonesin G via induction of GABARAPL1 M Fan, J Chen, J Gao, W Xue, Y Wang, W Li, L Zhou, X Li, C Jiang, Y Sun, ... Cell death & disease 11 (8), 635, 2020 | 32 | 2020 |
| Andrographolide sulfonate ameliorates chronic colitis induced by TNBS in mice via decreasing inflammation and fibrosis J Gao, J Cui, H Zhong, Y Li, W Liu, C Jiao, J Gao, C Jiang, W Guo, Q Xu International Immunopharmacology 83, 106426, 2020 | 30 | 2020 |
| Diptoindonesin G promotes ERK-mediated nuclear translocation of p-STAT1 (Ser727) and cell differentiation in AML cells J Gao, M Fan, G Xiang, J Wang, X Zhang, W Guo, X Wu, Y Sun, Y Gu, ... Cell death & disease 8 (5), e2765-e2765, 2017 | 30 | 2017 |
| Anti-inflammatory actions of Caesalpinin M2 in experimental colitis as a selective glucocoricoid receptor modulator G Xiang, M Fan, Y Ma, M Wang, J Gao, J Chen, X Li, W Xue, Y Wang, ... Biochemical Pharmacology 150, 150-159, 2018 | 28 | 2018 |
| Typically inhibiting USP14 promotes autophagy in M1-like macrophages and alleviates CLP-induced sepsis F Xu, Y Ma, W Huang, J Gao, M Guo, J Li, L Kong, G Liang, R Du, Q Xu, ... Cell Death & Disease 11 (8), 666, 2020 | 27 | 2020 |
