Mitoxantrone targets human ubiquitin-specific peptidase 11 (USP11) and is a potent inhibitor of pancreatic cancer cell survival RA Burkhart, Y Peng, ZA Norris, RM Tholey, VA Talbott, Q Liang, Y Ai, ... Molecular Cancer Research 11 (8), 901-911, 2013 | 153 | 2013 |
HuR posttranscriptionally regulates WEE1: implications for the DNA damage response in pancreatic cancer cells S Lal, RA Burkhart, N Beeharry, V Bhattacharjee, ER Londin, ... Cancer research 74 (4), 1128-1140, 2014 | 110 | 2014 |
Posttranscriptional upregulation of IDH1 by HuR establishes a powerful survival phenotype in pancreatic cancer cells M Zarei, S Lal, SJ Parker, A Nevler, A Vaziri-Gohar, K Dukleska, ... Cancer research 77 (16), 4460-4471, 2017 | 102 | 2017 |
Crawling through time: transition of snails to slugs dating back to the Paleozoic, based on mitochondrial phylogenomics M Medina, S Lal, Y Vallès, TL Takaoka, BA Dayrat, JL Boore, T Gosliner Marine Genomics 4 (1), 51-59, 2011 | 74 | 2011 |
Posttranscriptional regulation of PARG mRNA by HuR facilitates DNA repair and resistance to PARP inhibitors SN Chand, M Zarei, MJ Schiewer, AR Kamath, C Romeo, S Lal, ... Cancer research 77 (18), 5011-5025, 2017 | 71 | 2017 |
Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer JD Steffen, RM Tholey, MF Langelier, JL Planck, MJ Schiewer, S Lal, ... Cancer research 74 (1), 31-37, 2014 | 63 | 2014 |
The role of PENNYWISE and POUND-FOOLISH in the maintenance of the shoot apical meristem in Arabidopsis N Ung, S Lal, HMS Smith Plant physiology 156 (2), 605-614, 2011 | 63 | 2011 |
Regulation of the SQUAMOSA PROMOTER-BINDING PROTEIN-LIKE genes/microRNA156 module by the homeodomain proteins PENNYWISE and POUND-FOOLISH in Arabidopsis S Lal, LB Pacis, HMS Smith Molecular plant 4 (6), 1123-1132, 2011 | 54 | 2011 |
CRISPR knockout of the HuR gene causes a xenograft lethal phenotype S Lal, EC Cheung, M Zarei, R Preet, SN Chand, NC Mambelli-Lisboa, ... Molecular Cancer Research 15 (6), 696-707, 2017 | 53 | 2017 |
Specification of reproductive meristems requires the combined function of SHOOT MERISTEMLESS and floral integrators FLOWERING LOCUS T and FD during Arabidopsis inflorescence … HMS Smith, N Ung, S Lal, J Courtier Journal of experimental botany 62 (2), 583-593, 2011 | 48 | 2011 |
dCK expression correlates with 5-fluorouracil efficacy and HuR cytoplasmic expression in pancreatic cancer: a dual-institutional follow-up with the RTOG 9704 trial F McAllister, DM Pineda, M Jimbo, S Lal, RA Burkhart, J Moughan, ... Cancer biology & therapy 15 (6), 688-698, 2014 | 47 | 2014 |
WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner S Lal, M Zarei, SN Chand, E Dylgjeri, NC Mambelli-Lisboa, MJ Pishvaian, ... Scientific reports 6 (1), 33323, 2016 | 38 | 2016 |
MUC1 Promoter–Driven DTA as a Targeted Therapeutic Strategy against Pancreatic Cancer RM Tholey, S Lal, M Jimbo, RA Burkhart, FF Blanco, JA Cozzitorto, ... Molecular Cancer Research 13 (3), 439-448, 2015 | 25 | 2015 |
RNA-binding Protein HuR Regulates Both Mutant and Wild-type IDH1 in IDH1-mutated Cancer Mahsa Zarei, Shruti Lal, Ali Vaziri-Gohar, Kevin O'Hayer, Venugopal Gunda ... Molecular Cancer Research 18 (0557), 2018 | 21* | 2018 |
Studying RNA-binding protein interactions with target mRNAs in eukaryotic cells: native ribonucleoprotein immunoprecipitation (RIP) assays JA Cozzitorto, M Jimbo, S Chand, F Blanco, S Lal, M Gilbert, JM Winter, ... Nuclear Bodies and Noncoding RNAs: Methods and Protocols, 239-246, 2015 | 16 | 2015 |
Discovery and characterization of ZL-2201, a potent, highly selective, and orally bioavailable small-molecule DNA-PK inhibitor S Lal, NE Bhola, BC Sun, Y Chen, T Huang, V Morton, KX Chen, S Xia, ... Cancer Research Communications 3 (9), 1731-1742, 2023 | 2 | 2023 |
988 Sequence alterations in the WEE1 non-coding region is a facilitator and marker for pancreatic tumorigenesis S Lal, F Blanco, TP Yeo, CJ Yeo, JR Brody, JM Winter Gastrointestinal Endoscopy 79 (5), AB188, 2014 | 2 | 2014 |
Development of NTX-472, a formulated mRNA therapy targeting CD20, CD19, and CD47, for treatment of B-cell lymphoma. A Sallets, W Liu, S Lal, G Adusumilli, A Sharma, S Bandi, P Dhungel, ... Journal of Clinical Oncology 42 (16_suppl), 2537-2537, 2024 | | 2024 |
NTX-470, a novel multispecific T cell engager expressed from mRNA targets PSMA and STEAP1 prostate cancer antigens to generate enhanced functional activity C Rae, S Adusumilli, S Bandi, S Lal, P Dhungel, K Ferry, S Gholizadeh, ... Cancer Research 84 (6_Supplement), 6725-6725, 2024 | | 2024 |
1359 NTX-0471, engineered multivalent SIRPa and bispecific SIRPa-antiCCR4 molecules demonstrate superior activity providing path for mRNA expressed in-vivo biologics G Kannan, A Sallets, G Adusumilli, S Bandi, S Lal, R Low, W Liu, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |