| MCM5 as a target of BET inhibitors in thyroid cancer cells C Mio, E Lavarone, K Conzatti, F Baldan, B Toffoletto, C Puppin, S Filetti, ... Endocrine-related cancer 23 (4), 335-347, 2016 | 45 | 2016 |
| SGK1 is a critical component of an AKT-independent pathway essential for PI3K-mediated tumor development and maintenance A Orlacchio, M Ranieri, M Brave, VA Arciuch, T Forde, D De Martino, ... Cancer research 77 (24), 6914-6926, 2017 | 39 | 2017 |
| Obatoclax kills anaplastic thyroid cancer cells by inducing lysosome neutralization and necrosis D Champa, A Orlacchio, B Patel, M Ranieri, AA Shemetov, VV Verkhusha, ... Oncotarget 7 (23), 34453, 2016 | 32 | 2016 |
| The role of toll-like receptors (TLRs) mediated inflammation in pancreatic cancer pathophysiology A Orlacchio, P Mazzone International Journal of Molecular Sciences 22 (23), 12743, 2021 | 23 | 2021 |
| PI3K blockage synergizes with PLK1 inhibition preventing endoreduplication and enhancing apoptosis in anaplastic thyroid cancer D De Martino, E Yilmaz, A Orlacchio, M Ranieri, K Zhao, A Di Cristofano Cancer letters 439, 56-65, 2018 | 20 | 2018 |
| Viral Manipulation of the Host Epigenome as a Driver of Virus-Induced Oncogenesis SHAA Soliman, A Orlacchio, F Verginelli Microorganisms 9 (6), 1179, 2021 | 13 | 2021 |
| RETRACTED ARTICLE: AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing GI Laliotis, E Chavdoula, MD Paraskevopoulou, A Kaba, A La Ferlita, ... Nature Communications 12 (1), 4624, 2021 | 12 | 2021 |
| Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality A Orlacchio, AE Stark, C Foray, F Amari, T Sheetz, E Reese, A Tessari, ... PloS one 13 (9), e0201030, 2018 | 12 | 2018 |
| Serum and glucocorticoid-inducible kinase 1 (Sgk1) in nsclc therapy I Guerriero, G Monaco, V Coppola, A Orlacchio Pharmaceuticals 13 (11), 413, 2020 | 11 | 2020 |
| Understanding tricky cellular and molecular interactions in pancreatic tumor microenvironment: New food for thought A Agostini, A Orlacchio, C Carbone, I Guerriero Frontiers in Immunology 13, 876291, 2022 | 9 | 2022 |
| IWS1 phosphorylation promotes cell proliferation and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the cell cycle-regulated U2AF2 RNA splicing GI Laliotis, E Chavdoula, MD Paraskevopoulou, AD Kaba, A La Ferlita, ... bioRxiv, 2020.07. 14.195297, 2020 | 5 | 2020 |
| tagging enhances histochemical and biochemical detection of Ran Binding Protein 9 in vivo and reveals its interaction with nucleolin DV Shimaa H. A. Soliman, Aaron E. Stark, Miranda L. Gardner, Sean W ... Scientific reports, 2020 | 5 | 2020 |
| Abstract PO010: The inhibition of IWS1 phosphorylation promotes genomic instability, the cGAS/STING pathway activation and PD-L1 levels, through the U2AF2 alternative RNA … GI Laliotis, E Chavdoula, A Kaba, A La Ferlita, V Anastas, A Orlacchio, ... Cancer Immunology Research 9 (2_Supplement), PO010-PO010, 2021 | 4 | 2021 |
| Abstract PO-011: IWS1 phosphorylation promotes tumor growth and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the epigenetic regulation of U2AF2 … GI Laliotis, E Chavdoula, MD Paraskevopoulou, A Kaba, A La Ferlita, ... Cancer Research 80 (23_Supplement), PO-011-PO-011, 2020 | 3 | 2020 |
| Alternative RNA splicing of U2AF2, induced by AKT3-phosphorylated IWS1, promotes tumor growth, by activating a CDCA5-pERK positive feedback loop GI Laliotis, E Chavdoula, MD Paraskevopoulou, V Anastas, I Vlachos, ... Cancer Research 80 (16_Supplement), 3649-3649, 2020 | 3 | 2020 |
| Abstract LB-183: Sensitivity of cancer cells to oncolytic viruses is defined by IWS1 phosphorylation dependent epigenetic regulation of U2AF2 splicing and nucleocytoplasmic … GI Laliotis, AD Kenney, A Orlacchio, V Coppola, JS Yount, PN Tsichlis Cancer Research 80 (16_Supplement), LB-183-LB-183, 2020 | 3 | 2020 |
| IWS1 phosphorylation by AKT kinase controls the nucleocytoplasmic export of type I IFNs and the sensitivity of lung adenocarcinoma cells to oncolytic viral infection, through … GI Laliotis, AD Kenney, E Chavdoula, A Orlacchio, AK Kaba, AL Ferlita, ... bioRxiv, 2020.12. 26.424461, 2020 | 2 | 2020 |
| RETRACTED ARTICLE: Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to … GI Laliotis, AD Kenney, E Chavdoula, A Orlacchio, A Kaba, A La Ferlita, ... Communications biology 4 (1), 1179, 2021 | 1 | 2021 |
| RANBP9 as potential therapeutic target in non-small cell lung cancer VC Anna Tessari, Shimaa H. A. Soliman, Arturo Orlacchio, Marina Capece ... J Cancer Metastasis Treat, 2020 | 1 | 2020 |
| RANBP9 presence affects levels of Tip60 and activated p53 in lung cancer cells in response to DNA damage S Soliman, A Orlacchio, A Tessari, M Capece, R Visone, C Croce, ... Cancer Research 79 (13_Supplement), 3514-3514, 2019 | 1 | 2019 |
