Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy A Bierhaus, T Fleming, S Stoyanov, A Leffler, A Babes, C Neacsu, ... Nature medicine 18 (6), 926-933, 2012 | 552 | 2012 |
The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons A Leffler, MJ Fischer, D Rehner, S Kienel, K Kistner, SK Sauer, NR Gavva, ... The Journal of clinical investigation 118 (2), 763-776, 2008 | 242 | 2008 |
Methylglyoxal activates nociceptors through transient receptor potential channel A1 (TRPA1): a possible mechanism of metabolic neuropathies MJ Eberhardt, MR Filipovic, A Leffler, J de la Roche, K Kistner, MJ Fischer, ... Journal of Biological Chemistry 287 (34), 28291-28306, 2012 | 212 | 2012 |
Rat peripheral nerve components release calcitonin gene-related peptide and prostaglandin E2 in response to noxious stimuli: evidence that nervi nervorum are nociceptors SK Sauer, GM Bove, B Averbeck, PW Reeh Neuroscience 92 (1), 319-325, 1999 | 147 | 1999 |
Muscarinic M2 receptors on peripheral nerve endings: a molecular target of antinociception N Bernardini, C Roza, SK Sauer, J Gomeza, J Wess, PW Reeh The Journal of Neuroscience 22 (12), RC229, 2002 | 104 | 2002 |
Sensitized peripheral nociception in experimental diabetes of the rat D Fuchs, F Birklein, PW Reeh, SK Sauer PAIN® 151 (2), 496-505, 2010 | 103 | 2010 |
Morphological evidence for functional capsaicin receptor expression and calcitonin gene-related peptide exocytosis in isolated peripheral nerve axons of the mouse N Bernardini, W Neuhuber, PW Reeh, SK Sauer Neuroscience 126 (3), 585-590, 2004 | 102 | 2004 |
Excitatory nicotinic and desensitizing muscarinic (M2) effects on C-nociceptors in isolated rat skin N Bernardini, SK Sauer, R Haberberger, MJM Fischer, PW Reeh Journal of Neuroscience 21 (9), 3295-3302, 2001 | 101 | 2001 |
Pro-and anti-inflammatory actions of ricinoleic acid: similarities and differences with capsaicin C Vieira, S Fetzer, SK Sauer, S Evangelista, B Averbeck, M Kress, ... Naunyn-Schmiedeberg's archives of pharmacology 364, 87-95, 2001 | 86 | 2001 |
Photosensitization in porphyrias and photodynamic therapy involves TRPA1 and TRPV1 A Babes, SK Sauer, L Moparthi, TI Kichko, C Neacsu, B Namer, ... Journal of Neuroscience 36 (19), 5264-5278, 2016 | 78 | 2016 |
Proton‐induced calcitonin gene‐related peptide release from rat sciatic nerve axons, in vitro, involving TRPV1 MJM Fischer, PW Reeh, SK Sauer European Journal of Neuroscience 18 (4), 803-810, 2003 | 78 | 2003 |
TRPV1, TRPA1, and CB1 in the isolated vagus nerve–axonal chemosensitivity and control of neuropeptide release K Weller, PW Reeh, SK Sauer Neuropeptides 45 (6), 391-400, 2011 | 72 | 2011 |
Calcitonin gene-related peptide release from intact isolated dorsal root and trigeminal ganglia M Eberhardt, T Hoffmann, SK Sauer, K Messlinger, PW Reeh, ... Neuropeptides 42 (3), 311-317, 2008 | 68 | 2008 |
Noxious heat‐induced CGRP release from rat sciatic nerve axons in vitro SK Sauer, PW Reeh, GM Bove European Journal of Neuroscience 14 (8), 1203-1208, 2001 | 62 | 2001 |
Non-associative defensive responses of rats to ferret odor CV Masini, S Sauer, J White, HEW Day, S Campeau Physiology & behavior 87 (1), 72-81, 2006 | 61 | 2006 |
Stimulated prostaglandin E2 release from rat skin, in vitro SK Sauer, D Schäfer, M Kress, PW Reeh Life sciences 62 (22), 2045-2055, 1998 | 56 | 1998 |
Sensory transduction in peripheral nerve axons elicits ectopic action potentials T Hoffmann, SK Sauer, RE Horch, PW Reeh Journal of Neuroscience 28 (24), 6281-6284, 2008 | 55 | 2008 |
Muscarinic M2 receptors inhibit heat-induced CGRP release from isolated rat skin N Bernardini, PW Reeh, SK Sauer Neuroreport 12 (11), 2457-2460, 2001 | 47 | 2001 |
A new paradigm to understand and treat diabetic neuropathy A Hidmark, T Fleming, S Vittas, M Mendler, D Deshpande, JB Groener, ... Experimental and Clinical Endocrinology & Diabetes 226 (04), 201-207, 2014 | 46 | 2014 |
Methylglyoxal causes pain and hyperalgesia in human through C-fiber activation MM Düll, K Riegel, J Tappenbeck, V Ries, M Strupf, T Fleming, SK Sauer, ... Pain 160 (11), 2497-2507, 2019 | 45 | 2019 |