Mutational heterogeneity in cancer and the search for new cancer-associated genes MS Lawrence, P Stojanov, P Polak, GV Kryukov, K Cibulskis, ... Nature 499 (7457), 214-218, 2013 | 5906 | 2013 |
Initial genome sequencing and analysis of multiple myeloma MA Chapman, MS Lawrence, JJ Keats, K Cibulskis, C Sougnez, ... Nature 471 (7339), 467-472, 2011 | 1734 | 2011 |
The genomic complexity of primary human prostate cancer MF Berger, MS Lawrence, F Demichelis, Y Drier, K Cibulskis, ... Nature 470 (7333), 214-220, 2011 | 1451 | 2011 |
Punctuated evolution of prostate cancer genomes SC Baca, D Prandi, MS Lawrence, JM Mosquera, A Romanel, Y Drier, ... Cell 153 (3), 666-677, 2013 | 1443 | 2013 |
Expanded encyclopaedias of DNA elements in the human and mouse genomes JE Moore, MJ Purcaro, HE Pratt, CB Epstein, N Shoresh, J Adrian, T Kawli, ... Nature 583 (7818), 699-710, 2020 | 1325 | 2020 |
Insulator dysfunction and oncogene activation in IDH mutant gliomas WA Flavahan, Y Drier, BB Liau, SM Gillespie, AS Venteicher, ... Nature 529 (7584), 110-114, 2016 | 1316 | 2016 |
Melanoma genome sequencing reveals frequent PREX2 mutations MF Berger, E Hodis, TP Heffernan, YL Deribe, MS Lawrence, ... Nature 485 (7399), 502-506, 2012 | 889 | 2012 |
Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation N Gagliani, MCA Vesely, A Iseppon, L Brockmann, H Xu, NW Palm, ... Nature 523 (7559), 221-225, 2015 | 851 | 2015 |
Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion AJ Bass, MS Lawrence, LE Brace, AH Ramos, Y Drier, K Cibulskis, ... Nature genetics 43 (10), 964-968, 2011 | 373 | 2011 |
Pathway-based personalized analysis of cancer Y Drier, M Sheffer, E Domany Proceedings of the National Academy of Sciences 110 (16), 6388-6393, 2013 | 347 | 2013 |
SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation X Wang, RS Lee, BH Alver, JR Haswell, S Wang, J Mieczkowski, Y Drier, ... Nature genetics 49 (2), 289-295, 2017 | 328 | 2017 |
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma Y Drier, MJ Cotton, KE Williamson, SM Gillespie, RJH Ryan, MJ Kluk, ... Nature genetics 48 (3), 265-272, 2016 | 267 | 2016 |
Large-scale implementation of pooled RNA extraction and RT-PCR for SARS-CoV-2 detection R Ben-Ami, A Klochendler, M Seidel, T Sido, O Gurel-Gurevich, ... Clinical Microbiology and Infection, 2020 | 238 | 2020 |
Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs WA Flavahan, Y Drier, SE Johnstone, ML Hemming, DR Tarjan, E Hegazi, ... Nature 575 (7781), 229-233, 2019 | 203 | 2019 |
Targeting FGFR overcomes EMT-mediated resistance in EGFR mutant non-small cell lung cancer S Raoof, IJ Mulford, H Frisco-Cabanos, V Nangia, D Timonina, E Labrot, ... Oncogene 38 (37), 6399-6413, 2019 | 188 | 2019 |
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer N Shah, P Wang, J Wongvipat, WR Karthaus, W Abida, J Armenia, ... Elife 6, e27861, 2017 | 168 | 2017 |
Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors P Cejas, Y Drier, KMA Dreijerink, LAA Brosens, V Deshpande, CB Epstein, ... Nature medicine 25 (8), 1260-1265, 2019 | 160 | 2019 |
Large-scale topological changes restrain malignant progression in colorectal cancer SE Johnstone, A Reyes, Y Qi, C Adriaens, E Hegazi, K Pelka, JH Chen, ... Cell 182 (6), 1474-1489. e23, 2020 | 158 | 2020 |
Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability Y Drier, MS Lawrence, SL Carter, C Stewart, SB Gabriel, ES Lander, ... Genome research 23 (2), 228-235, 2013 | 158 | 2013 |
Genetic interrogation of circulating multiple myeloma cells at single-cell resolution JG Lohr, S Kim, J Gould, B Knoechel, Y Drier, MJ Cotton, D Gray, N Birrer, ... Science translational medicine 8 (363), 363ra147-363ra147, 2016 | 145 | 2016 |