Leishmaniasis treatment: update of possibilities for drug repurposing VV Andrade Neto, EF Cunha Junior, VS Faioes, TP Martins, RL Silva, ... Frontiers in BioScience, 2018 | 78 | 2018 |
LQB-118, an orally active pterocarpanquinone, induces selective oxidative stress and apoptosis in Leishmania amazonensis GA Ribeiro, EF Cunha-Júnior, RO Pinheiro, SAG da-Silva, ... Journal of Antimicrobial Chemotherapy 68 (4), 789-799, 2013 | 68 | 2013 |
Pterocarpanquinones, aza-pterocarpanquinone and derivatives: synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis CD Buarque, GCG Militão, DJB Lima, LV Costa-Lotufo, C Pessoa, ... Bioorganic & medicinal chemistry 19 (22), 6885-6891, 2011 | 58 | 2011 |
Antileishmanial activity of amides from Piper amalago and synthetic analogs V da Silva Carrara, EF Cunha-Júnior, EC Torres-Santos, AG Corrêa, ... Revista Brasileira de Farmacognosia 23 (3), 447-454, 2013 | 52 | 2013 |
The pharmacological inhibition of sterol biosynthesis in Leishmania is counteracted by enhancement of LDL endocytosis VV Andrade-Neto, NNT Cicco, EF Cunha-Junior, MM Canto-Cavalheiro, ... Acta tropica 119 (2-3), 194-198, 2011 | 45 | 2011 |
HPLC Analysis of Supercritical Carbon Dioxide and Compressed Propane Extracts from Piper amalago L. with Antileishmanial Activity VS Carrara, LZ Serra, L Cardozo-Filho, EF Cunha-Júnior, ... Molecules 17 (1), 15-33, 2011 | 43 | 2011 |
Effectiveness of the local or oral delivery of the novel naphthopterocarpanquinone LQB-118 against cutaneous leishmaniasis EF da Cunha-Júnior, W Pacienza-Lima, GA Ribeiro, CD Netto, ... Journal of antimicrobial chemotherapy 66 (7), 1555-1559, 2011 | 43 | 2011 |
Oral pentamidine-loaded poly (d, l-lactic-co-glycolic) acid nanoparticles: an alternative approach for leishmaniasis treatment IV Valle, ME Machado, CCB Araújo, EF da Cunha-Junior, ... Nanotechnology 30 (45), 455102, 2019 | 38 | 2019 |
Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice EF Cunha-Júnior, VV Andrade-Neto, ML Lima, TA da Costa-Silva, ... PLoS Neglected Tropical Diseases 11 (1), e0005281, 2017 | 28 | 2017 |
In Vitro and In Vivo Studies of the Trypanocidal Effect of Novel Quinolines ASG Nefertiti, MM Batista, PB Da Silva, DGJ Batista, CF Da Silva, ... Antimicrobial Agents and Chemotherapy 62 (2), 10.1128/aac. 01936-17, 2018 | 27 | 2018 |
Supercritical Fluid Extraction of Pyrrolidine Alkaloid from Leaves of Piper amalago L. VS Carrara, LC Filho, VAS Garcia, VS Faiões, EF Cunha-Júnior, ... Evidence‐Based Complementary and Alternative Medicine 2017 (1), 7401748, 2017 | 27 | 2017 |
Preclinical studies evaluating subacute toxicity and therapeutic efficacy of LQB-118 in experimental visceral leishmaniasis EF Cunha-Júnior, TM Martins, MM Canto-Cavalheiro, PR Marques, ... Antimicrobial Agents and Chemotherapy 60 (6), 3794-3801, 2016 | 26 | 2016 |
Pterocarpanquinone LQB-118 Induces Apoptosis in Leishmania (Viannia) braziliensis and Controls Lesions in Infected Hamsters L Costa, RO Pinheiro, PML Dutra, RF Santos, EF Cunha-Junior, ... PLoS One 9 (10), e109672, 2014 | 26 | 2014 |
Antileishmanial Activity of Ezetimibe: Inhibition of Sterol Biosynthesis, In Vitro Synergy with Azoles, and Efficacy in Experimental Cutaneous Leishmaniasis VV Andrade-Neto, EF Cunha-Júnior, MM Canto-Cavalheiro, GC Atella, ... Antimicrobial Agents and Chemotherapy 60 (11), 6844-6852, 2016 | 23 | 2016 |
Sertraline delivered in phosphatidylserine liposomes is effective in an experimental model of visceral leishmaniasis MM Romanelli, TA Costa-Silva, E Cunha-Junior, D Dias Ferreira, ... Frontiers in cellular and infection microbiology 9, 353, 2019 | 20 | 2019 |
Monocyclic nitro-heteroaryl nitrones with dual mechanism of activation: synthesis and antileishmanial activity JS Pacheco, DS Costa, EF Cunha-Júnior, VV Andrade-Neto, AH Fairlamb, ... ACS Medicinal Chemistry Letters 12 (9), 1405-1412, 2021 | 12 | 2021 |
Naphthoquinones and derivatives for chemotherapy: perspectives and limitations of their anti-trypanosomatids activities L Dantas-Pereira, EF Cunha-Junior, VV Andrade-Neto, JF Bower, ... Current Pharmaceutical Design 27 (15), 1807-1824, 2021 | 11 | 2021 |
Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection CF da Silva, DGJ Batista, JS de Araújo, EF Cunha-Junior, CE Stephens, ... Drug Design, Development and Therapy, 1095-1105, 2017 | 11 | 2017 |
Second-generation pterocarpanquinones: synthesis and antileishmanial activity VS Faiões, LCRM Frota, EF Cunha-Junior, JCF Barcellos, TD Silva, ... Journal of Venomous Animals and Toxins including Tropical Diseases 24, 35, 2018 | 10 | 2018 |
Anti-parasitic effect of novel amidines against Trypanosoma cruzi: phenotypic and in silico absorption, distribution, metabolism, excretion and toxicity analysis ASDAG NEFERTITI, MM BATISTA, PB DA SILVA, EC TORRES-SANTOS, ... Parasitology Open 3, e5, 2017 | 8 | 2017 |