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Cunha-Junior EF
Cunha-Junior EF
在 ioc.fiocruz.br 的电子邮件经过验证
标题
引用次数
引用次数
年份
Leishmaniasis treatment: update of possibilities for drug repurposing
VV Andrade Neto, EF Cunha Junior, VS Faioes, TP Martins, RL Silva, ...
Frontiers in BioScience, 2018
782018
LQB-118, an orally active pterocarpanquinone, induces selective oxidative stress and apoptosis in Leishmania amazonensis
GA Ribeiro, EF Cunha-Júnior, RO Pinheiro, SAG da-Silva, ...
Journal of Antimicrobial Chemotherapy 68 (4), 789-799, 2013
682013
Pterocarpanquinones, aza-pterocarpanquinone and derivatives: synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis
CD Buarque, GCG Militão, DJB Lima, LV Costa-Lotufo, C Pessoa, ...
Bioorganic & medicinal chemistry 19 (22), 6885-6891, 2011
582011
Antileishmanial activity of amides from Piper amalago and synthetic analogs
V da Silva Carrara, EF Cunha-Júnior, EC Torres-Santos, AG Corrêa, ...
Revista Brasileira de Farmacognosia 23 (3), 447-454, 2013
522013
The pharmacological inhibition of sterol biosynthesis in Leishmania is counteracted by enhancement of LDL endocytosis
VV Andrade-Neto, NNT Cicco, EF Cunha-Junior, MM Canto-Cavalheiro, ...
Acta tropica 119 (2-3), 194-198, 2011
452011
HPLC Analysis of Supercritical Carbon Dioxide and Compressed Propane Extracts from Piper amalago L. with Antileishmanial Activity
VS Carrara, LZ Serra, L Cardozo-Filho, EF Cunha-Júnior, ...
Molecules 17 (1), 15-33, 2011
432011
Effectiveness of the local or oral delivery of the novel naphthopterocarpanquinone LQB-118 against cutaneous leishmaniasis
EF da Cunha-Júnior, W Pacienza-Lima, GA Ribeiro, CD Netto, ...
Journal of antimicrobial chemotherapy 66 (7), 1555-1559, 2011
432011
Oral pentamidine-loaded poly (d, l-lactic-co-glycolic) acid nanoparticles: an alternative approach for leishmaniasis treatment
IV Valle, ME Machado, CCB Araújo, EF da Cunha-Junior, ...
Nanotechnology 30 (45), 455102, 2019
382019
Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice
EF Cunha-Júnior, VV Andrade-Neto, ML Lima, TA da Costa-Silva, ...
PLoS Neglected Tropical Diseases 11 (1), e0005281, 2017
282017
In Vitro and In Vivo Studies of the Trypanocidal Effect of Novel Quinolines
ASG Nefertiti, MM Batista, PB Da Silva, DGJ Batista, CF Da Silva, ...
Antimicrobial Agents and Chemotherapy 62 (2), 10.1128/aac. 01936-17, 2018
272018
Supercritical Fluid Extraction of Pyrrolidine Alkaloid from Leaves of Piper amalago L.
VS Carrara, LC Filho, VAS Garcia, VS Faiões, EF Cunha-Júnior, ...
Evidence‐Based Complementary and Alternative Medicine 2017 (1), 7401748, 2017
272017
Preclinical studies evaluating subacute toxicity and therapeutic efficacy of LQB-118 in experimental visceral leishmaniasis
EF Cunha-Júnior, TM Martins, MM Canto-Cavalheiro, PR Marques, ...
Antimicrobial Agents and Chemotherapy 60 (6), 3794-3801, 2016
262016
Pterocarpanquinone LQB-118 Induces Apoptosis in Leishmania (Viannia) braziliensis and Controls Lesions in Infected Hamsters
L Costa, RO Pinheiro, PML Dutra, RF Santos, EF Cunha-Junior, ...
PLoS One 9 (10), e109672, 2014
262014
Antileishmanial Activity of Ezetimibe: Inhibition of Sterol Biosynthesis, In Vitro Synergy with Azoles, and Efficacy in Experimental Cutaneous Leishmaniasis
VV Andrade-Neto, EF Cunha-Júnior, MM Canto-Cavalheiro, GC Atella, ...
Antimicrobial Agents and Chemotherapy 60 (11), 6844-6852, 2016
232016
Sertraline delivered in phosphatidylserine liposomes is effective in an experimental model of visceral leishmaniasis
MM Romanelli, TA Costa-Silva, E Cunha-Junior, D Dias Ferreira, ...
Frontiers in cellular and infection microbiology 9, 353, 2019
202019
Monocyclic nitro-heteroaryl nitrones with dual mechanism of activation: synthesis and antileishmanial activity
JS Pacheco, DS Costa, EF Cunha-Júnior, VV Andrade-Neto, AH Fairlamb, ...
ACS Medicinal Chemistry Letters 12 (9), 1405-1412, 2021
122021
Naphthoquinones and derivatives for chemotherapy: perspectives and limitations of their anti-trypanosomatids activities
L Dantas-Pereira, EF Cunha-Junior, VV Andrade-Neto, JF Bower, ...
Current Pharmaceutical Design 27 (15), 1807-1824, 2021
112021
Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection
CF da Silva, DGJ Batista, JS de Araújo, EF Cunha-Junior, CE Stephens, ...
Drug Design, Development and Therapy, 1095-1105, 2017
112017
Second-generation pterocarpanquinones: synthesis and antileishmanial activity
VS Faiões, LCRM Frota, EF Cunha-Junior, JCF Barcellos, TD Silva, ...
Journal of Venomous Animals and Toxins including Tropical Diseases 24, 35, 2018
102018
Anti-parasitic effect of novel amidines against Trypanosoma cruzi: phenotypic and in silico absorption, distribution, metabolism, excretion and toxicity analysis
ASDAG NEFERTITI, MM BATISTA, PB DA SILVA, EC TORRES-SANTOS, ...
Parasitology Open 3, e5, 2017
82017
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