Trypanosoma cruzi: activities of lapachol and α-and β-lapachone derivatives against epimastigote and trypomastigote forms C Salas, RA Tapia, K Ciudad, V Armstrong, M Orellana, U Kemmerling, ... Bioorganic & medicinal chemistry 16 (2), 668-674, 2008 | 138 | 2008 |
Natural and synthetic naphthoquinones active against Trypanosoma cruzi: an initial step towards new drugs for Chagas disease C O Salas, M Faúndez, A Morello, J Diego Maya, R A Tapia Current medicinal chemistry 18 (1), 144-161, 2011 | 125 | 2011 |
Nerve growth factor-dependent activation of trkA receptors in the human ovary results in synthesis of follicle-stimulating hormone receptors and estrogen secretion C Salas, M Julio-Pieper, M Valladares, R Pommer, M Vega, ... The Journal of Clinical Endocrinology & Metabolism 91 (6), 2396-2403, 2006 | 119 | 2006 |
2-Phenylaminonaphthoquinones and related compounds: Synthesis, trypanocidal and cytotoxic activities I Sieveking, P Thomas, JC Estévez, N Quiñones, MA Cuéllar, J Villena, ... Bioorganic & medicinal chemistry 22 (17), 4609-4620, 2014 | 86 | 2014 |
Ciudad C Salas, RA Tapia K., Armstrong, V., Orellana, M., Kemmerling, U., Ferreira, J., Maya, JD …, 2008 | 76 | 2008 |
Synthesis, biological evaluation, and molecular simulation of chalcones and aurones as selective MAO‐B inhibitors N Morales‐Camilo, CO Salas, C Sanhueza, C Espinosa‐Bustos, ... Chemical biology & drug design 85 (6), 685-695, 2015 | 69 | 2015 |
Synthesis and antiprotozoal activity of naphthofuranquinones and naphthothiophenequinones containing a fused thiazole ring RA Tapia, L Alegria, CD Pessoa, C Salas, MJ Cortés, JA Valderrama, ... Bioorganic & medicinal chemistry 11 (10), 2175-2182, 2003 | 67 | 2003 |
Involvement of ETA receptors in the facilitation by endothelin‐1 of non‐adrenergic non‐cholinergic transmission in the rat urinary bladder MV Donoso, C Salas, G Sepulveda, J Lewin, A Fournier, ... British journal of pharmacology 111 (2), 473-482, 1994 | 58 | 1994 |
Synthesis and in vitro trypanocide activity of several polycyclic drimane-quinone derivatives MA Cuellar, C Salas, MJ Cortés, A Morello, JD Maya, MD Preite Bioorganic & medicinal chemistry 11 (12), 2489-2497, 2003 | 53 | 2003 |
Synthesis and pharmacophore modelling of 2, 6, 9-trisubstituted purine derivatives and their potential role as apoptosis-inducing agents in cancer cell lines J Calderón-Arancibia, C Espinosa-Bustos, Á Cañete-Molina, RA Tapia, ... Molecules 20 (4), 6808-6826, 2015 | 46 | 2015 |
Synthesis of dihydronaphthofurandiones and dihydrofuroquinolinediones with trypanocidal activity and analysis of their stereoelectronic properties RA Tapia, C Salas, A Morello, JD Maya, A Toro-Labbé Bioorganic & medicinal chemistry 12 (9), 2451-2458, 2004 | 46 | 2004 |
Nutritional composition, antioxidant activity and isolation of scopoletin from Senecio nutans: support of ancestral and new uses C Parra, E Soto, G León, CO Salas, M Heinrich, C Echiburú-Chau Natural Product Research 32 (6), 719-722, 2018 | 42 | 2018 |
N-Heterocyclic carbene copper (I) complex-catalyzed synthesis of 2-aryl benzoxazoles and benzothiazoles JI Urzúa, R Contreras, CO Salas, RA Tapia RSC advances 6 (85), 82401-82408, 2016 | 41 | 2016 |
Trypanothione reductase: a target for the development of anti-Trypanosoma cruzi drugs K Vázquez, M Paulino, C O Salas, J J Zarate-Ramos, B Vera, G Rivera Mini Reviews in Medicinal Chemistry 17 (11), 939-946, 2017 | 39 | 2017 |
New aryloxy-quinone derivatives as potential anti-Chagasic agents: Synthesis, trypanosomicidal activity, electrochemical properties, pharmacophore elucidation and 3D-QSAR analysis K Vázquez, C Espinosa-Bustos, J Soto-Delgado, RA Tapia, J Varela, ... RSC advances 5 (80), 65153-65166, 2015 | 38 | 2015 |
Synthesis of chalcones with antiproliferative activity on the SH-SY5Y neuroblastoma cell line: Quantitative Structure–Activity Relationship Models M Mellado, A Madrid, M Reyna, C Weinstein-Oppenheimer, J Mella, ... Medicinal Chemistry Research 27, 2414-2425, 2018 | 34 | 2018 |
Synthesis of indazol‐4, 7‐dione derivatives as potential trypanocidal agents RA Tapia, C Carrasco, S Ojeda, C Salas, JA Valderrama, A Morello, ... Journal of heterocyclic chemistry 39 (5), 1093-1096, 2002 | 34 | 2002 |
The selective cytotoxicity elicited by phytochemical extract from Senecio graveolens (Asteraceae) on breast cancer cells is enhanced by hypoxia C Echiburú-Chau, S Alfaro-Lira, N Brown, CO Salas, M Cuellar, ... International Journal of Oncology 44 (4), 1357-1364, 2014 | 32 | 2014 |
Synthesis of new phosphorescent imidoyl-indazol and phosphine mixed ligand Cu (I) complexes–structural characterization and photophysical properties AR Cabrera, IA Gonzalez, D Cortés-Arriagada, M Natali, H Berke, ... RSC advances 6 (7), 5141-5153, 2016 | 31 | 2016 |
State of the art of Smo antagonists for cancer therapy: Advances in the target receptor and new ligand structures C Espinosa-Bustos, J Mella, J Soto-Delgado, CO Salas Future Medicinal Chemistry 11 (6), 617-638, 2019 | 29 | 2019 |