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Lakshman Gunaratnam
Lakshman Gunaratnam
在 uwo.ca 的电子邮件经过验证
标题
引用次数
引用次数
年份
Kidney injury molecule–1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells
T Ichimura, EJP Asseldonk, BD Humphreys, L Gunaratnam, JS Duffield, ...
The Journal of clinical investigation 118 (5), 1657-1668, 2008
9332008
Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer
A Franovic, L Gunaratnam, K Smith, I Robert, D Patten, S Lee
Proceedings of the National Academy of Sciences 104 (32), 13092-13097, 2007
3242007
HIF activation by pH-dependent nucleolar sequestration of VHL
K Mekhail, L Gunaratnam, ME Bonicalzi, S Lee
Nature cell biology 6 (7), 642-647, 2004
3212004
Hypoxia inducible factor activates the transforming growth factor-α/epidermal growth factor receptor growth stimulatory pathway in VHL-/-renal cell carcinoma cells
L Gunaratnam, M Morley, A Franovic, N De Paulsen, K Mekhail, ...
Journal of Biological Chemistry 278 (45), 44966-44974, 2003
2832003
Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice
S Arai, K Kitada, T Yamazaki, R Takai, X Zhang, Y Tsugawa, R Sugisawa, ...
Nature medicine 22 (2), 183-193, 2016
2032016
HIF in kidney disease and development
L Gunaratnam, JV Bonventre
Journal of the American Society of Nephrology 20 (9), 1877-1887, 2009
1952009
Silencing of Epidermal Growth Factor Receptor Suppresses Hypoxia-Inducible Factor-2–Driven VHL−/− Renal Cancer
K Smith, L Gunaratnam, M Morley, A Franovic, K Mekhail, S Lee
Cancer research 65 (12), 5221-5230, 2005
1872005
Type I diabetes and multiple sclerosis patients target islet plus central nervous system autoantigens; nonimmunized nonobese diabetic mice can develop autoimmune encephalitis
S Winer, I Astsaturov, RK Cheung, L Gunaratnam, V Kubiak, MA Cortez, ...
The Journal of Immunology 166 (4), 2831-2841, 2001
1112001
Caspase-3 is a pivotal regulator of microvascular rarefaction and renal fibrosis after ischemia-reperfusion injury
B Yang, S Lan, M Dieudé, JP Sabo-Vatasescu, A Karakeussian-Rimbaud, ...
Journal of the American Society of Nephrology 29 (7), 1900-1916, 2018
1072018
Regulation of ubiquitin ligase dynamics by the nucleolus
K Mekhail, M Khacho, A Carrigan, RRJ Hache, L Gunaratnam, S Lee
The Journal of cell biology 170 (5), 733-744, 2005
1012005
Hydrogen sulfide treatment mitigates renal allograft ischemia-reperfusion injury during cold storage and improves early transplant kidney function and survival following …
I Lobb, M Davison, D Carter, W Liu, A Haig, L Gunaratnam, A Sener
The Journal of urology 194 (6), 1806-1815, 2015
892015
Multiple acquired renal carcinoma tumor capabilities abolished upon silencing of ADAM17
A Franovic, I Robert, K Smith, G Kurban, A Pause, L Gunaratnam, S Lee
Cancer research 66 (16), 8083-8090, 2006
802006
T cells of multiple sclerosis patients target a common environmental peptide that causes encephalitis in mice
S Winer, I Astsaturov, RK Cheung, K Schrade, L Gunaratnam, DD Wood, ...
The Journal of Immunology 166 (7), 4751-4756, 2001
802001
Kidney injury molecule-1 protects against Gα12 activation and tissue damage in renal ischemia-reperfusion injury
OZ Ismail, X Zhang, J Wei, A Haig, BM Denker, RS Suri, A Sener, ...
The American journal of pathology 185 (5), 1207-1215, 2015
732015
Kidney injury molecule-1 expression in IgA nephropathy and its correlation with hypoxia and tubulointerstitial inflammation
Q Lin, Y Chen, J Lv, H Zhang, J Tang, L Gunaratnam, X Li, L Yang
American Journal of Physiology-Renal Physiology 306 (8), F885-F895, 2014
522014
A randomized controlled trial of the effects of febuxostat therapy on adipokines and markers of kidney fibrosis in asymptomatic hyperuricemic patients with diabetic nephropathy
S Beddhu, R Filipowicz, B Wang, G Wei, X Chen, AC Roy, SL DuVall, ...
Canadian journal of kidney health and disease 3, 2054358116675343, 2016
512016
Short-term antibody response after 1 dose of BNT162b2 vaccine in patients receiving hemodialysis
R Goupil, M Benlarbi, W Beaubien-Souligny, AC Nadeau-Fredette, ...
Cmaj 193 (22), E793-E800, 2021
452021
Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis
R Gandhi, J Yi, J Ha, H Shi, O Ismail, S Nathoo, JV Bonventre, X Zhang, ...
American Journal of Physiology-Renal Physiology 307 (2), F205-F221, 2014
432014
Gα12 stimulates apoptosis in epithelial cells through JNK1-mediated Bcl-2 degradation and up-regulation of IκBα
V Yanamadala, H Negoro, L Gunaratnam, T Kong, BM Denker
Journal of Biological Chemistry 282 (33), 24352-24363, 2007
422007
Oxygen sensing by H+: implications for HIF and hypoxic cell memory
K Mekhail, M Khacho, L Gunaratnam, S Lee
Cell Cycle 3 (8), 1025-1027, 2004
402004
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