ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia HP Jia, DC Look, L Shi, M Hickey, L Pewe, J Netland, M Farzan, ... Journal of virology 79 (23), 14614-14621, 2005 | 1012 | 2005 |
Human beta-defensin-1: an antimicrobial peptide of urogenital tissues. EV Valore, CH Park, AJ Quayle, KR Wiles, PB McCray, T Ganz The Journal of clinical investigation 101 (8), 1633-1642, 1998 | 952 | 1998 |
Rapid “open-source” engineering of customized zinc-finger nucleases for highly efficient gene modification ML Maeder, S Thibodeau-Beganny, A Osiak, DA Wright, RM Anthony, ... Molecular cell 31 (2), 294-301, 2008 | 909 | 2008 |
Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung AA Pezzulo, XX Tang, MJ Hoegger, MH Abou Alaiwa, S Ramachandran, ... Nature 487 (7405), 109-113, 2012 | 878 | 2012 |
Lethal Infection of K18-hACE2 Mice Infected with Severe Acute Respiratory Syndrome Coronavirus PB McCray Jr, L Pewe, C Wohlford-Lenane, M Hickey, L Manzel, L Shi, ... Journal of virology 81 (2), 813-821, 2007 | 851 | 2007 |
Current prospects for RNA interference-based therapies BL Davidson, PB McCray Jr Nature Reviews Genetics 12 (5), 329-340, 2011 | 849 | 2011 |
Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs CS Rogers, DA Stoltz, DK Meyerholz, LS Ostedgaard, T Rokhlina, PJ Taft, ... Science 321 (5897), 1837-1841, 2008 | 834 | 2008 |
Production of β-defensins by human airway epithelia PK Singh, HP Jia, K Wiles, J Hesselberth, L Liu, BAD Conway, ... Proceedings of the National Academy of Sciences 95 (25), 14961-14966, 1998 | 799 | 1998 |
Discovery of five conserved β-defensin gene clusters using a computational search strategy BC Schutte, JP Mitros, JA Bartlett, JD Walters, HP Jia, MJ Welsh, ... Proceedings of the National Academy of Sciences 99 (4), 2129-2133, 2002 | 651 | 2002 |
Antimicrobial peptides in animals and their role in host defences KA Brogden, M Ackermann, PB McCray Jr, BF Tack International journal of antimicrobial agents 22 (5), 465-478, 2003 | 600 | 2003 |
Adherens junction protein nectin-4 is the epithelial receptor for measles virus MD Mühlebach, M Mateo, PL Sinn, S Prüfer, KM Uhlig, VHJ Leonard, ... Nature 480 (7378), 530-533, 2011 | 589 | 2011 |
Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth DA Stoltz, DK Meyerholz, AA Pezzulo, S Ramachandran, MP Rogan, ... Science translational medicine 2 (29), 29ra31-29ra31, 2010 | 545 | 2010 |
IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes R Channappanavar, AR Fehr, J Zheng, C Wohlford-Lenane, ... The Journal of clinical investigation 129 (9), 3625-3639, 2019 | 540 | 2019 |
The solution structures of the human β-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus DJ Schibli, HN Hunter, V Aseyev, TD Starner, JM Wiencek, PB McCray, ... Journal of Biological Chemistry 277 (10), 8279-8289, 2002 | 502 | 2002 |
Production of β-defensin antimicrobial peptides by the oral mucosa and salivary glands M Mathews, HP Jia, JM Guthmiller, G Losh, S Graham, GK Johnson, ... Infection and immunity 67 (6), 2740-2745, 1999 | 489 | 1999 |
Rapid generation of a mouse model for Middle East respiratory syndrome J Zhao, K Li, C Wohlford-Lenane, SS Agnihothram, C Fett, J Zhao, ... Proceedings of the National Academy of Sciences 111 (13), 4970-4975, 2014 | 482 | 2014 |
Middle East respiratory syndrome coronavirus causes multiple organ damage and lethal disease in mice transgenic for human dipeptidyl peptidase 4 K Li, C Wohlford-Lenane, S Perlman, J Zhao, AK Jewell, LR Reznikov, ... The Journal of infectious diseases 213 (5), 712-722, 2016 | 481 | 2016 |
Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-α secretion through IKK regulation of NF-κB S Sanlioglu, CM Williams, L Samavati, NS Butler, G Wang, PB McCray, ... Journal of Biological Chemistry 276 (32), 30188-30198, 2001 | 475 | 2001 |
Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors–design, biosafety, and production PL Sinn, SL Sauter, PB McCray Gene therapy 12 (14), 1089-1098, 2005 | 461 | 2005 |
A SARS-CoV-2 infection model in mice demonstrates protection by neutralizing antibodies AO Hassan, JB Case, ES Winkler, LB Thackray, NM Kafai, AL Bailey, ... Cell 182 (3), 744-753. e4, 2020 | 452 | 2020 |