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Opher S. Kornfeld, PhD
Opher S. Kornfeld, PhD
Director, Translational Research and Development, SPARK NS
在 stanford.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
NINJ1 mediates plasma membrane rupture during lytic cell death
N Kayagaki, OS Kornfeld, BL Lee, IB Stowe, K O’Rourke, Q Li, ...
Nature 591 (7848), 131-136, 2021
3652021
Correcting mitochondrial fusion by manipulating mitofusin conformations
A Franco, RN Kitsis, JA Fleischer, E Gavathiotis, OS Kornfeld, G Gong, ...
Nature 540 (7631), 74-79, 2016
2282016
Mitochondrial reactive oxygen species at the heart of the matter: new therapeutic approaches for cardiovascular diseases
OS Kornfeld, S Hwang, MH Disatnik, CH Chen, N Qvit, D Mochly-Rosen
Circulation research 116 (11), 1783-1799, 2015
1912015
IRF2 transcriptionally induces GSDMD expression for pyroptosis
N Kayagaki, BL Lee, IB Stowe, OS Kornfeld, K O'Rourke, KM Mirrashidi, ...
Science signaling 12 (582), eaax4917, 2019
1342019
Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation
BL Lee, IB Stowe, A Gupta, OS Kornfeld, M Roose-Girma, K Anderson, ...
Journal of Experimental Medicine 215 (9), 2279-2288, 2018
1252018
Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo
OS Kornfeld, N Qvit, B Haileselassie, M Shamloo, P Bernardi, ...
Scientific reports 8 (1), 14034, 2018
562018
The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: a tangled duo unchained
AU Joshi, OS Kornfeld, D Mochly-Rosen
Cell Calcium 60 (3), 218-234, 2016
502016
Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury
N Kayagaki, IB Stowe, K Alegre, I Deshpande, S Wu, Z Lin, OS Kornfeld, ...
Nature, 1-3, 2023
272023
Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection
E Bjanes, RG Sillas, R Matsuda, B Demarco, T Fettrelet, AA DeLaney, ...
PLoS Pathogens 17 (10), e1009967, 2021
262021
Engineered Substrate‐Specific Delta PKC Antagonists to Enhance Cardiac Therapeutics
N Qvit, OS Kornfeld, D Mochly‐Rosen
Angewandte Chemie 128 (50), 15901-15908, 2016
182016
Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
N Qvit, OS Kornfeld
Journal of Visualized Experiments, e53589, 2016
102016
Epigenetic and transcriptional control of gasdermins
C Cadena, OS Kornfeld, BL Lee, N Kayagaki
Seminars in Immunology 70, 101841, 2023
12023
Highly multiplexed, image-based pooled screens in primary cells and tissues with PerturbView
T Kudo, AM Meireles, R Moncada, Y Chen, P Wu, J Gould, X Hu, ...
bioRxiv, 2023.12. 26.573143, 2023
2023
A novel pharmacological modulator abrogates physiological mitochondrial fission though specifically inhibiting the Mff‐Drp1 protein‐protein interaction
OS Kornfeld, N Qvit, M Shamloo, D Mochly‐Rosen
The FASEB Journal 32, 543.21-543.21, 2018
2018
Novel Pharmacological Modulators of Mitochondrial Function in Cell Physiology and Pathology
OS Kornfeld
Stanford University, 2018
2018
A novel pharmacological tool blocks physiological mitochondrial fission through specifically inhibiting the Mff-Drp1 protein-protein interaction.
OS Kornfeld, N Qvit, M Monbureau, M Halpain, M Shamloo, ...
MOLECULAR BIOLOGY OF THE CELL 28, 2017
2017
Utilizing a novel peptide Inhibitor to modulate mitochondrial dynamics and investigate Drp1's physiological roles.
OS Kornfeld, N Qvit, M Disatnik, M Monbureau, M Halpain, A Evans, ...
MOLECULAR BIOLOGY OF THE CELL 26, 2015
2015
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