PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo DR Alessi, A Cuenda, P Cohen, DT Dudley, AR Saltiel Journal of Biological Chemistry 270 (46), 27489-27494, 1995 | 4138 | 1995 |
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1 A Cuenda, J Rouse, YN Doza, R Meier, P Cohen, TF Gallagher, ... FEBS letters 364 (2), 229-233, 1995 | 2469 | 1995 |
p38 MAP-kinases pathway regulation, function and role in human diseases A Cuenda, S Rousseau Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1773 (8), 1358-1375, 2007 | 1766 | 2007 |
The p38/RK mitogen‐activated protein kinase pathway regulates interleukin‐6 synthesis response to tumor necrosis factor. R Beyaert, A Cuenda, W Vanden Berghe, S Plaisance, JC Lee, ... The EMBO journal 15 (8), 1914-1923, 1996 | 815 | 1996 |
Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that … M Goedert, A Cuenda, M Craxton, R Jakes, P Cohen The EMBO journal 16 (12), 3563-3571, 1997 | 537 | 1997 |
Activation of stress‐activated protein kinase‐3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK … A Cuenda, P Cohen, V Buée‐Scherrer, M Goedert The EMBO Journal, 1997 | 456 | 1997 |
Stress-activated protein kinase-2/p38 and a rapamycin-sensitive pathway are required for C2C12 myogenesis A Cuenda, P Cohen Journal of Biological Chemistry 274 (7), 4341-4346, 1999 | 389 | 1999 |
Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases M Goedert, M Hasegawa, R Jakes, S Lawler, A Cuenda, P Cohen FEBS letters 409 (1), 57-62, 1997 | 389 | 1997 |
BIRB796 inhibits all p38 MAPK isoforms in vitro and in vivo Y Kuma, G Sabio, J Bain, N Shpiro, R Márquez, A Cuenda Journal of Biological Chemistry 280 (20), 19472-19479, 2005 | 379 | 2005 |
p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP G Sabio, JSC Arthur, Y Kuma, M Peggie, J Carr, V Murray‐Tait, F Centeno, ... The EMBO journal 24 (6), 1134-1145, 2005 | 294 | 2005 |
p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient CA Hazzalin, E Cano, A Cuenda, MJ Barratt, P Cohen, LC Mahadevan Current Biology 6 (8), 1028-1031, 1996 | 290 | 1996 |
Stress-activated protein kinase-3 interacts with the PDZ domain of α1-syntrophin: a mechanism for specific substrate recognition M Hasegawa, A Cuenda, MG Spillantini, GM Thomas, V Buée-Scherrer, ... Journal of Biological Chemistry 274 (18), 12626-12631, 1999 | 216 | 1999 |
Differential activation of p38MAPK isoforms by MKK6 and MKK3 G Remy, AM Risco, FA Iñesta-Vaquera, B González-Terán, G Sabio, ... Cellular signalling 22 (4), 660-667, 2010 | 188 | 2010 |
Cellular stresses and cytokines activate multiple mitogen‐activated‐protein kinase kinase homologues in PC12 and KB cells R Meier, J Rouse, A Cuenda, AR Nebreda, P Cohen European journal of biochemistry 236 (3), 796-805, 1996 | 177 | 1996 |
CXCL12 and C5a trigger cell migration via a PAK1/2-p38α MAPK-MAPKAP-K2-HSP27 pathway S Rousseau, I Dolado, V Beardmore, N Shpiro, R Marquez, AR Nebreda, ... Cellular signalling 18 (11), 1897-1905, 2006 | 174 | 2006 |
Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress‐and cytokine‐stimulated monocytes and epithelial cells. A Cuenda, G Alonso, N Morrice, M Jones, R Meier, P Cohen, AR Nebreda The EMBO journal 15 (16), 4156-4164, 1996 | 165 | 1996 |
Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38δ at Thr50 promotes microtubule assembly C Feijoo, DG Campbell, R Jakes, M Goedert, A Cuenda Journal of cell science 118 (2), 397-408, 2005 | 160 | 2005 |
p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation A Risco, C del Fresno, A Mambol, D Alsina-Beauchamp, KF MacKenzie, ... Proceedings of the National Academy of Sciences 109 (28), 11200-11205, 2012 | 143 | 2012 |
p38-γ–dependent gene silencing restricts entry into the myogenic differentiation program MA Gillespie, F Le Grand, A Scimè, S Kuang, J Von Maltzahn, V Seale, ... Journal of Cell Biology 187 (7), 991-1005, 2009 | 141 | 2009 |
Mitogen-activated protein kinase kinase 4 (MKK4) A Cuenda The international journal of biochemistry & cell biology 32 (6), 581-587, 2000 | 140 | 2000 |