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David Gallo
David Gallo
Repare Therapeutics
在 reparerx.com 的电子邮件经过验证
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引用次数
引用次数
年份
HELB is a feedback inhibitor of DNA end resection
J Tkáč, G Xu, H Adhikary, JTF Young, D Gallo, C Escribano-Díaz, ...
Molecular cell 61 (3), 405-418, 2016
1612016
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition
D Gallo, JTF Young, J Fourtounis, G Martino, A Álvarez-Quilón, C Bernier, ...
Nature 604 (7907), 749-756, 2022
912022
Haploinsufficiency of an RB–E2F1–Condensin II complex leads to aberrant replication and aneuploidy
CH Coschi, CA Ishak, D Gallo, A Marshall, S Talluri, J Wang, MJ Cecchini, ...
Cancer discovery 4 (7), 840-853, 2014
842014
A role for USP7 in DNA replication
M Jagannathan, T Nguyen, D Gallo, N Luthra, GW Brown, V Saridakis, ...
Molecular and cellular biology 34 (1), 132-145, 2014
772014
Rad5 recruits error-prone DNA polymerases for mutagenic repair of ssDNA gaps on undamaged templates
D Gallo, TH Kim, B Szakal, X Saayman, A Narula, Y Park, D Branzei, ...
Molecular cell 73 (5), 900-914. e9, 2019
582019
Assembly of Slx4 signaling complexes behind DNA replication forks
A Balint, TH Kim, D Gallo, JR Cussiol, FM Bastos de Oliveira, A Yimit, J Ou, ...
The EMBO journal 34 (16), 2182-2197, 2015
512015
Comparative chemogenomics to examine the mechanism of action of DNA-targeted platinum-acridine anticancer agents
K Cheung-Ong, KT Song, Z Ma, D Shabtai, AY Lee, D Gallo, LE Heisler, ...
ACS chemical biology 7 (11), 1892-1901, 2012
502012
Flap endonuclease overexpression drives genome instability and DNA damage hypersensitivity in a PCNA-dependent manner
JR Becker, D Gallo, W Leung, T Croissant, YM Thu, HD Nguyen, TK Starr, ...
Nucleic acids research 46 (11), 5634-5650, 2018
402018
Analysis of replicating yeast chromosomes by DNA combing
D Gallo, G Wang, CM Yip, GW Brown
Cold Spring Harbor Protocols 2016 (2), pdb. prot085118, 2016
332016
Post-replication repair: Rad5/HLTF regulation, activity on undamaged templates, and relationship to cancer
D Gallo, GW Brown
Critical reviews in biochemistry and molecular biology 54 (3), 301-332, 2019
222019
Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma
L Tamayo-Orrego, D Gallo, F Racicot, A Bemmo, S Mohan, B Ho, ...
Nature cancer 1 (8), 840-854, 2020
192020
Hyperphosphorylation by cyclin B/CDK1 in mitosis resets CUX1 DNA binding clock at each cell cycle
L Sansregret, D Gallo, M Santaguida, L Leduy, R Harada, A Nepveu
Journal of biological chemistry 285 (43), 32834-32843, 2010
172010
Single-molecule analysis of replicating yeast chromosomes
D Gallo, G Wang, CM Yip, GW Brown
Cold Spring Harbor Protocols 2016 (2), pdb. top077784, 2016
42016
Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair
M Larin, D Gallo, L Tamblyn, J Yang, H Liao, N Sabat, GW Brown, ...
Nucleic acids research 42 (15), 9807-9820, 2014
42014
CDK12 loss leads to replication stress and sensitivity to combinations of the ATR inhibitor camonsertib (RP-3500) with PARP inhibitors
J Setton, D Gallo, D Glodzik, B Kaiser, S Braverman, T Ubhi, S Fournier, ...
European Journal of Cancer 174, S99-S100, 2022
22022
Targeting CCNE1 amplified ovarian and endometrial cancers by combined inhibition of PKMYT1 and ATR
H Xu, E George, D Gallo, S Medvedev, X Wang, R Kryczka, ML Hyer, ...
Research Square, 2024
2024
15O Targeting CCNE1-amplified ovarian and endometrial cancers by combined inhibition of PKYMT1 and ATR
F Simpkins, E George, D Gallo, S Medvedev, X Wang, R Kryczka, M Hyer, ...
ESMO Open 9, 2024
2024
Abstract A023: Preclinical development of PKMYT1 and WEE1 inhibitor combinations
D Gallo, F Shah, R Stocco, P Baruah, J Fourtounis, R Kryczka, ML Hyer, ...
Molecular Cancer Therapeutics 22 (12_Supplement), A023-A023, 2023
2023
Abstract C163: KRAS alterations combined with TP53 mutations as novel synthetic lethal genomic lesions for PKMYT1 inhibition
ML Hyer, J Fourtounis, D Gallo, V Bhaskaran, R Stocco, R Kryczka, ...
NaN, C163-C163, 2023
2023
Abstract B057: Preclinical development of PKMYT1 and ATR inhibitor combinations
D Gallo, ML Hyer, G Martino, A Pertrone, E Aguado-Fraile, R Kryczka, ...
NaN, B057-B057, 2023
2023
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