Detection of ultra-rare mutations by next-generation sequencing MW Schmitt, SR Kennedy, JJ Salk, EJ Fox, JB Hiatt, LA Loeb Proceedings of the National Academy of Sciences 109 (36), 14508-14513, 2012 | 1138 | 2012 |
Detecting ultralow-frequency mutations by Duplex Sequencing SR Kennedy, MW Schmitt, EJ Fox, BF Kohrn, JJ Salk, EH Ahn, MJ Prindle, ... Nature protocols 9 (11), 2586-2606, 2014 | 548 | 2014 |
Mutational heterogeneity in human cancers: origin and consequences JJ Salk, EJ Fox, LA Loeb Annual Review of Pathology: Mechanisms of Disease 5 (1), 51-75, 2010 | 369 | 2010 |
Accuracy of next generation sequencing platforms EJ Fox, KS Reid-Bayliss, MJ Emond, LA Loeb Next generation, sequencing & applications 1, 2014 | 336 | 2014 |
Sequencing small genomic targets with high efficiency and extreme accuracy MW Schmitt, EJ Fox, MJ Prindle, KS Reid-Bayliss, LD True, JP Radich, ... Nature methods 12 (5), 423-425, 2015 | 186 | 2015 |
Oxidative stress is not a major contributor to somatic mitochondrial DNA mutations LS Itsara, SR Kennedy, EJ Fox, S Yu, JJ Hewitt, M Sanchez-Contreras, ... PLoS genetics 10 (2), e1003974, 2014 | 184 | 2014 |
CENP‐F expression is associated with poor prognosis and chromosomal instability in patients with primary breast cancer SL O'Brien, A Fagan, EJP Fox, RC Millikan, AC Culhane, DJ Brennan, ... International journal of cancer 120 (7), 1434-1443, 2007 | 134 | 2007 |
Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies WM Gallagher, OE Bergin, M Rafferty, ZD Kelly, IM Nolan, EJP Fox, ... Carcinogenesis 26 (11), 1856-1867, 2005 | 134 | 2005 |
Mutational spectra of aflatoxin B1 in vivo establish biomarkers of exposure for human hepatocellular carcinoma S Chawanthayatham, CC Valentine III, BI Fedeles, EJ Fox, LA Loeb, ... Proceedings of the National Academy of Sciences 114 (15), E3101-E3109, 2017 | 121 | 2017 |
Hypoxia induces mitochondrial mutagenesis and dysfunction in inflammatory arthritis M Biniecka, E Fox, W Gao, CT Ng, DJ Veale, U Fearon, J O'Sullivan Arthritis & Rheumatism 63 (8), 2172-2182, 2011 | 116 | 2011 |
Combination of SELDI-TOF-MS and data mining provides early-stage response prediction for rectal tumors undergoing multimodal neoadjuvant therapy FM Smith, WM Gallagher, E Fox, RB Stephens, E Rexhepaj, ... Annals of surgery 245 (2), 259-266, 2007 | 104 | 2007 |
Interaction of soft condensed materials with living cells: phenotype/transcriptome correlations for the hydrophobic effect LT Allen, EJP Fox, I Blute, ZD Kelly, Y Rochev, AK Keenan, KA Dawson, ... Proceedings of the National Academy of Sciences 100 (11), 6331-6336, 2003 | 101 | 2003 |
Medullary carcinoma of the pancreas in a man with hereditary nonpolyposis colorectal cancer due to a mutation of the MSH2 mismatch repair gene N Banville, R Geraghty, E Fox, DT Leahy, A Green, D Keegan, ... Human pathology 37 (11), 1498-1502, 2006 | 97 | 2006 |
Mitochondrial mutagenesis correlates with the local inflammatory environment in arthritis LC Harty, M Biniecka, J O'Sullivan, E Fox, K Mulhall, DJ Veale, U Fearon Annals of the rheumatic diseases 71 (4), 582-588, 2012 | 94 | 2012 |
The basis of cellular and regional vulnerability in Alzheimer’s disease D Mrdjen, EJ Fox, SA Bukhari, KS Montine, SC Bendall, TJ Montine Acta neuropathologica 138, 729-749, 2019 | 93 | 2019 |
Lethal mutagenesis: targeting the mutator phenotype in cancer EJ Fox, LA Loeb Seminars in cancer biology 20 (5), 353-359, 2010 | 89 | 2010 |
Increased topoisomerase IIα expression in colorectal cancer is associated with advanced disease and chemotherapeutic resistance via inhibition of apoptosis A Coss, M Tosetto, EJ Fox, B Sapetto-Rebow, S Gorman, BN Kennedy, ... Cancer letters 276 (2), 228-238, 2009 | 84 | 2009 |
Do mutator mutations fuel tumorigenesis? EJ Fox, MJ Prindle, LA Loeb Cancer and Metastasis Reviews 32, 353-361, 2013 | 81 | 2013 |
Cancer genome sequencing—an interim analysis EJ Fox, JJ Salk, LA Loeb Cancer research 69 (12), 4948-4950, 2009 | 81 | 2009 |
Growth arrest-specific gene 6 expression in human breast cancer O Mc Cormack, WY Chung, P Fitzpatrick, F Cooke, B Flynn, M Harrison, ... British journal of cancer 98 (6), 1141-1146, 2008 | 76 | 2008 |