Cancer stem cells in glioblastoma JD Lathia, SC Mack, EE Mulkearns-Hubert, CLL Valentim, JN Rich Genes & development 29 (12), 1203-1217, 2015 | 1635 | 2015 |
Cancer stem cells: targeting the roots of cancer, seeds of metastasis, and sources of therapy resistance V Adorno-Cruz, G Kibria, X Liu, M Doherty, DJ Junk, D Guan, C Hubert, ... Cancer research 75 (6), 924-929, 2015 | 248 | 2015 |
Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion B Otvos, DJ Silver, EE Mulkearns-Hubert, AG Alvarado, SM Turaga, ... Stem cells 34 (8), 2026-2039, 2016 | 225 | 2016 |
Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis TJ Alban, AG Alvarado, MD Sorensen, D Bayik, J Volovetz, E Serbinowski, ... JCI insight 3 (21), 2018 | 174 | 2018 |
Glioblastoma cancer stem cells evade innate immune suppression of self-renewal through reduced TLR4 expression AG Alvarado, PS Thiagarajan, EE Mulkearns-Hubert, DJ Silver, JS Hale, ... Cell stem cell 20 (4), 450-461. e4, 2017 | 174 | 2017 |
Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo V Khurana, I Elson-Schwab, TA Fulga, KA Sharp, CA Loewen, ... PLoS genetics 6 (7), e1001026, 2010 | 159 | 2010 |
S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila ML Steinhilb, D Dias‐Santagata, EE Mulkearns, JM Shulman, J Biernat, ... Journal of neuroscience research 85 (6), 1271-1278, 2007 | 126 | 2007 |
Differential connexin function enhances self-renewal in glioblastoma M Hitomi, LP Deleyrolle, EE Mulkearns-Hubert, A Jarrar, M Li, M Sinyuk, ... Cell reports 11 (7), 1031-1042, 2015 | 119 | 2015 |
Inhibition of CXCR7 extends survival following irradiation of brain tumours in mice and rats MJ Walters, K Ebsworth, RD Berahovich, MET Penfold, SC Liu, ... British journal of cancer 110 (5), 1179-1188, 2014 | 98 | 2014 |
The clathrin adaptor Dab2 recruits EH domain scaffold proteins to regulate integrin β1 endocytosis A Teckchandani, EE Mulkearns, TW Randolph, N Toida, JA Cooper Molecular biology of the cell 23 (15), 2905-2916, 2012 | 83 | 2012 |
Cancer connectors: connexins, gap junctions, and communication M Sinyuk, EE Mulkearns-Hubert, O Reizes, J Lathia Frontiers in oncology 8, 646, 2018 | 82 | 2018 |
Development of a fluorescent reporter system to delineate cancer stem cells in triple-negative breast cancer PS Thiagarajan, M Hitomi, JS Hale, AG Alvarado, B Otvos, M Sinyuk, ... Stem cells 33 (7), 2114-2125, 2015 | 82 | 2015 |
Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase PS Thiagarajan, M Sinyuk, SM Turaga, EE Mulkearns-Hubert, JS Hale, ... Nature communications 9 (1), 578, 2018 | 77 | 2018 |
FCH domain only-2 organizes clathrin-coated structures and interacts with Disabled-2 for low-density lipoprotein receptor endocytosis EE Mulkearns, JA Cooper Molecular biology of the cell 23 (7), 1330-1342, 2012 | 59 | 2012 |
STAT3 activation by leptin receptor is essential for TNBC stem cell maintenance PS Thiagarajan, Q Zheng, M Bhagrath, EE Mulkearns-Hubert, MG Myers, ... Endocrine-related cancer 24 (8), 415-426, 2017 | 49 | 2017 |
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity DC Watson, D Bayik, S Storevik, SS Moreino, SA Sprowls, J Han, ... Nature cancer 4 (5), 648-664, 2023 | 45 | 2023 |
Phage display discovery of novel molecular targets in glioblastoma-initiating cells JK Liu, D Lubelski, DL Schonberg, Q Wu, JS Hale, WA Flavahan, ... Cell Death & Differentiation 21 (8), 1325-1339, 2014 | 41 | 2014 |
Coordination of self-renewal in glioblastoma by integration of adhesion and microRNA signaling AG Alvarado, SM Turaga, P Sathyan, EE Mulkearns-Hubert, B Otvos, ... Neuro-oncology 18 (5), 656-666, 2016 | 40 | 2016 |
Development of a Cx46 targeting strategy for cancer stem cells EE Mulkearns-Hubert, LA Torre-Healy, DJ Silver, JT Eurich, D Bayik, ... Cell reports 27 (4), 1062-1072. e5, 2019 | 34 | 2019 |
Connexins in cancer: Jekyll or Hyde? EE Mulkearns-Hubert, O Reizes, JD Lathia Biomolecules 10 (12), 1654, 2020 | 32 | 2020 |