Therapeutic challenges and current immunomodulatory strategies in targeting the immunosuppressive pancreatic tumor microenvironment CK Looi, FFL Chung, CO Leong, SF Wong, R Rosli, CW Mai Journal of Experimental & Clinical Cancer Research 38, 1-23, 2019 | 146 | 2019 |
Human mitochondrial DNA is extensively methylated in a non-CpG context V Patil, C Cuenin, F Chung, JRR Aguilera, N Fernandez-Jimenez, ... Nucleic Acids Research, gkz762, 2019 | 117 | 2019 |
Mutant p53-R273H mediates cancer cell survival and anoikis resistance through AKT-dependent suppression of BCL2-modifying factor (BMF) BS Tan, KH Tiong, HL Choo, F Fei-Lei Chung, LW Hii, SH Tan, IKS Yap, ... Cell death & disease 6 (7), e1826-e1826, 2015 | 103 | 2015 |
Toxicity of single-walled carbon nanotubes LC Ong, FFL Chung, YF Tan, CO Leong Archives of toxicology 90, 103-118, 2016 | 82 | 2016 |
Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma LJW Pua, CW Mai, FFL Chung, ASB Khoo, CO Leong, WM Lim, LW Hii International Journal of Molecular Sciences 23 (3), 1108, 2022 | 81 | 2022 |
Fibroblast growth factor receptor 4 (FGFR4) and fibroblast growth factor 19 (FGF19) autocrine enhance breast cancer cells survival KH Tiong, BS Tan, HL Choo, FFL Chung, LW Hii, SH Tan, NTW Khor, ... Oncotarget 7 (36), 57633, 2016 | 79 | 2016 |
Cudraflavone C induces tumor-specific apoptosis in colorectal cancer cells through inhibition of the phosphoinositide 3-kinase (PI3K)-AKT pathway HC Soo, FFL Chung, KH Lim, VA Yap, TD Bradshaw, LW Hii, SH Tan, ... PLoS One 12 (1), e0170551, 2017 | 69 | 2017 |
Metformin synergizes 5-fluorouracil, epirubicin, and cyclophosphamide (FEC) combination therapy through impairing intracellular ATP production and DNA repair in breast cancer … JSS Soo, CH Ng, SH Tan, RA Malik, YC Teh, BS Tan, GF Ho, MH See, ... Apoptosis 20, 1373-1387, 2015 | 66 | 2015 |
Carcinogenicity of acrolein, crotonaldehyde, and arecoline MM Marques, FA Beland, DW Lachenmeier, DH Phillips, FL Chung, ... The Lancet Oncology, 2020 | 62 | 2020 |
Antagonistic and synergistic epigenetic modulation using orthologous CRISPR/dCas9-based modular system G Josipović, V Tadić, M Klasić, V Zanki, I Bečeheli, F Chung, A Ghantous, ... Nucleic acids research 47 (18), 9637-9657, 2019 | 55 | 2019 |
Targeting Legumain As a Novel Therapeutic Strategy in Cancers CW Mai, FFL Chung, CO Leong Current drug targets 18 (11), 1259-1268, 2017 | 55 | 2017 |
The Promises and Challenges of Toxico-Epigenomics: Environmental Chemicals and Their Impacts on the Epigenome FFL Chung, Z Herceg Environmental Health Perspectives 128 (1), 015001, 2020 | 54 | 2020 |
Jerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1) FFL Chung, PFTM Tan, VJ Raja, BS Tan, KH Lim, TS Kam, LW Hii, ... Scientific reports 7 (1), 42504, 2017 | 51 | 2017 |
A Bis-benzopyrroloisoquinoline Alkaloid Incorporating a Cyclobutane Core and a Chlorophenanthroindolizidine Alkaloid with Cytotoxic Activity from Ficus fistulosa var. tengerensis AAQ Al-Khdhairawi, P Krishnan, CW Mai, FFL Chung, CO Leong, ... Journal of Natural Products 80 (10), 2734-2740, 2017 | 45 | 2017 |
Identification of inhibitors synergizing gemcitabine sensitivity in the squamous subtype of pancreatic ductal adenocarcinoma (PDAC) JL Er, PN Goh, CY Lee, YJ Tan, LW Hii, CW Mai, FFL Chung, CO Leong Apoptosis 23, 343-355, 2018 | 40 | 2018 |
Histone deacetylase (HDAC) inhibitors and doxorubicin combinations target both breast cancer stem cells and non-stem breast cancer cells simultaneously LW Hii, FFL Chung, JSS Soo, BS Tan, CW Mai, CO Leong Breast cancer research and treatment 179, 615-629, 2020 | 39 | 2020 |
Cytochrome P450 2W1 (CYP2W1) in colorectal cancers F Fei-Lei Chung, C Wai Mai, P Yuen Ng, CO Leong Current cancer drug targets 16 (1), 71-78, 2016 | 36 | 2016 |
Aristolochic acid-associated cancers: a public health risk in need of global action S Das, S Thakur, M Korenjak, VS Sidorenko, FFL Chung, J Zavadil Nature Reviews Cancer 22 (10), 576-591, 2022 | 33 | 2022 |
Inhibition of attachment of oral bacteria to immortalized human gingival fibroblasts (HGF-1) by tea extracts and tea components Y Wang, FFL Chung, SM Lee, GA Dykes BMC research notes 6, 1-5, 2013 | 33 | 2013 |
Sphingosine Kinase 1 Regulates the Survival of Breast Cancer Stem Cells and Non-stem Breast Cancer Cells by Suppression of STAT1 LW Hii, FFL Chung, CW Mai, ZY Yee, HH Chan, VJ Raja, NE Dephoure, ... Cells 9 (4), 886, 2020 | 30 | 2020 |