Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia M Ilander, U Olsson-Strömberg, H Schlums, J Guilhot, O Brück, ... Leukemia 31 (5), 1108-1116, 2017 | 226 | 2017 |
Immunogenomic landscape of hematological malignancies O Dufva, P Pölönen, O Brück, MAI Keränen, J Klievink, J Mehtonen, ... Cancer Cell 38 (3), 380-399. e13, 2020 | 115 | 2020 |
Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia H Kuusanmäki, AM Leppä, P Pölönen, M Kontro, O Dufva, D Deb, ... Haematologica 105 (3), 708, 2020 | 94 | 2020 |
Immune cell contexture in the bone marrow tumor microenvironment impacts therapy response in CML O Brück, S Blom, O Dufva, R Turkki, H Chheda, A Ribeiro, P Kovanen, ... Leukemia 32 (7), 1643-1656, 2018 | 81 | 2018 |
Immune cell constitution in the tumor microenvironment predicts the outcome in diffuse large B-cell lymphoma M Autio, SK Leivonen, O Brück, S Mustjoki, JM Jørgensen, ... Haematologica 106 (3), 718, 2021 | 79 | 2021 |
PD-L1+ tumor-associated macrophages and PD-1+ tumor-infiltrating lymphocytes predict survival in primary testicular lymphoma M Pollari, O Brück, T Pellinen, P Vähämurto, ML Karjalainen-Lindsberg, ... haematologica 103 (11), 1908, 2018 | 75 | 2018 |
Somatic STAT3 mutations in Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia P Savola, O Brück, T Olson, T Kelkka, MJ Kauppi, PE Kovanen, S Kytölä, ... haematologica 103 (2), 304, 2018 | 59 | 2018 |
Implementing a functional precision medicine tumor board for acute myeloid leukemia D Malani, A Kumar, O Brück, M Kontro, B Yadav, M Hellesøy, ... Cancer Discovery 12 (2), 388-401, 2022 | 55 | 2022 |
Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL H Hohtari, O Brück, S Blom, R Turkki, M Sinisalo, PE Kovanen, ... Leukemia 33 (7), 1570-1582, 2019 | 52 | 2019 |
Somatic mutations in lymphocytes in patients with immune-mediated aplastic anemia S Lundgren, MAI Keränen, M Kankainen, J Huuhtanen, G Walldin, ... Leukemia 35 (5), 1365-1379, 2021 | 44 | 2021 |
Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival O Brück, O Dufva, H Hohtari, S Blom, R Turkki, M Ilander, P Kovanen, ... Blood advances 4 (2), 274-286, 2020 | 43 | 2020 |
Lumican is upregulated in osteoarthritis and contributes to TLR4-induced pro-inflammatory activation of cartilage degradation and macrophage polarization G Barreto, B Senturk, L Colombo, O Brück, P Neidenbach, G Salzmann, ... Osteoarthritis and cartilage 28 (1), 92-101, 2020 | 42 | 2020 |
T-cell inflamed tumor microenvironment predicts favorable prognosis in primary testicular lymphoma SK Leivonen, M Pollari, O Brück, T Pellinen, M Autio, ... haematologica 104 (2), 338, 2019 | 42 | 2019 |
Dasatinib reversibly disrupts endothelial vascular integrity by increasing non-muscle myosin II contractility in a ROCK-dependent manner A Kreutzman, B Colom-Fernández, AM Jiménez, M Ilander, ... Clinical Cancer Research 23 (21), 6697-6707, 2017 | 41 | 2017 |
Characterization of polydactyly chondrocytes and their use in cartilage engineering E Cavalli, C Levinson, M Hertl, N Broguiere, O Brück, S Mustjoki, ... Scientific reports 9 (1), 4275, 2019 | 34 | 2019 |
Prognostic impact of tumor-associated macrophages on survival is checkpoint dependent in classical Hodgkin lymphoma K Karihtala, SK Leivonen, O Brück, ML Karjalainen-Lindsberg, S Mustjoki, ... Cancers 12 (4), 877, 2020 | 31 | 2020 |
Machine learning of bone marrow histopathology identifies genetic and clinical determinants in patients with MDS OE Brück, SE Lallukka-Brück, HR Hohtari, A Ianevski, FT Ebeling, ... Blood cancer discovery 2 (3), 238-249, 2021 | 27 | 2021 |
Spatial immunoprofiling of the intratumoral and peritumoral tissue of renal cell carcinoma patients O Brück, MH Lee, R Turkki, I Uski, P Penttilä, L Paavolainen, P Kovanen, ... Modern Pathology 34 (12), 2229-2241, 2021 | 23 | 2021 |
Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease D Kim, G Park, J Huuhtanen, S Lundgren, RK Khajuria, AM Hurtado, ... Nature communications 11 (1), 2246, 2020 | 22 | 2020 |
STAT3 Mutation Is Associated with STAT3 Activation in CD30+ ALK− ALCL EI Andersson, O Brück, T Braun, S Mannisto, L Saikko, S Lagström, ... Cancers 12 (3), 702, 2020 | 22 | 2020 |