Genome wide analysis of nucleosome density histone acetylation and HDAC function in fission yeast M Wirén, RA Silverstein, I Sinha, J Walfridsson, H Lee, P Laurenson, ... The EMBO journal 24 (16), 2906-2918, 2005 | 172 | 2005 |
Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions X Zhu, M Wirén, I Sinha, NN Rasmussen, T Linder, S Holmberg, K Ekwall, ... Molecular cell 22 (2), 169-178, 2006 | 139 | 2006 |
Genome-wide profiling of AP-1–regulated transcription provides insights into the invasiveness of triple-negative breast cancer C Zhao, Y Qiao, P Jonsson, J Wang, L Xu, P Rouhi, I Sinha, Y Cao, ... Cancer research 74 (14), 3983-3994, 2014 | 138 | 2014 |
Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients H Kirchner, I Sinha, H Gao, MA Ruby, M Schönke, JM Lindvall, R Barrès, ... Molecular metabolism 5 (3), 171-183, 2016 | 131 | 2016 |
Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity E Kvedaraite, L Hertwig, I Sinha, A Ponzetta, I Hed Myrberg, M Lourda, ... Proceedings of the National Academy of Sciences 118 (6), e2018587118, 2021 | 130 | 2021 |
AP-1 is a key regulator of proinflammatory cytokine TNFα-mediated triple-negative breast cancer progression Y Qiao, H He, P Jonsson, I Sinha, C Zhao, K Dahlman-Wright Journal of Biological Chemistry 291 (10), 5068-5079, 2016 | 122 | 2016 |
The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes I Dahlman, I Sinha, H Gao, D Brodin, A Thorell, M Ryden, DP Andersson, ... International Journal of Obesity 39 (6), 910-919, 2015 | 108 | 2015 |
Peroxisome proliferator-activated receptor γ coactivator-1 α isoforms selectively regulate multiple splicing events on target genes V Martínez-Redondo, PR Jannig, JC Correia, DMS Ferreira, I Cervenka, ... Journal of Biological Chemistry 291 (29), 15169-15184, 2016 | 82 | 2016 |
The epigenetic signature of systemic insulin resistance in obese women P Arner, AS Sahlqvist, I Sinha, H Xu, X Yao, D Waterworth, D Rajpal, ... Diabetologia 59, 2393-2405, 2016 | 75 | 2016 |
The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women P Arner, I Sinha, A Thorell, M Rydén, K Dahlman-Wright, I Dahlman Clinical epigenetics 7, 1-13, 2015 | 72 | 2015 |
High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19 PNAS 118 (40), 2021 | 67* | 2021 |
RING finger protein 31 promotes p53 degradation in breast cancer cells J Zhu, C Zhao, T Zhuang, P Jonsson, I Sinha, C Williams, S Strömblad, ... Oncogene 35 (15), 1955-1964, 2016 | 60 | 2016 |
A nucleosome turnover map reveals that the stability of histone H4 Lys20 methylation depends on histone recycling in transcribed chromatin JP Svensson, M Shukla, V Menendez-Benito, U Norman-Axelsson, ... Genome research 25 (6), 872-883, 2015 | 59 | 2015 |
Genome-wide patterns of histone modifications in fission yeast I Sinha Karolinska Institutet (https://openarchive.ki.se/xmlui/handle/10616/40012), 2010 | 57* | 2010 |
Specific functions for the fission yeast Sirtuins Hst2 and Hst4 in gene regulation and retrotransposon silencing M Durand‐Dubief, I Sinha, F Fagerström‐Billai, C Bonilla, A Wright, ... The EMBO Journal 26 (10), 2477-2488, 2007 | 57 | 2007 |
Estrogen receptor α promotes breast cancer by reprogramming choline metabolism M Jia, T Andreassen, L Jensen, TF Bathen, I Sinha, H Gao, C Zhao, ... Cancer research 76 (19), 5634-5646, 2016 | 52 | 2016 |
Differential methylation in inflammation and type 2 diabetes genes in siblings born before and after maternal bariatric surgery D Berglind, P Müller, M Willmer, I Sinha, P Tynelius, E Näslund, ... Obesity 24 (1), 250-261, 2016 | 51 | 2016 |
c-Jun/AP-1 overexpression reprograms ERα signaling related to tamoxifen response in ERα-positive breast cancer H He, I Sinha, R Fan, LA Haldosen, F Yan, C Zhao, K Dahlman-Wright Oncogene 37 (19), 2586-2600, 2018 | 47 | 2018 |
Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism JC Correia, J Massart, JF de Boer, M Porsmyr-Palmertz, ... Molecular metabolism 4 (12), 891-902, 2015 | 46 | 2015 |
Positional differences of axon growth rates between sensory neurons encoded by Runx3 F Lallemend, U Sterzenbach, S Hadjab‐Lallemend, JB Aquino, ... The EMBO Journal 31 (18), 3718-3729, 2012 | 41 | 2012 |