The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitors P Benisch, T Schilling, L Klein-Hitpass, SP Frey, L Seefried, ... Public Library of Science 7 (9), e45142, 2012 | 221 | 2012 |
BPS804 anti‐sclerostin antibody in adults with moderate osteogenesis imperfecta: results of a randomized phase 2a trial FH Glorieux, JP Devogelaer, M Durigova, S Goemaere, S Hemsley, ... Journal of Bone and Mineral Research 32 (7), 1496-1504, 2017 | 152 | 2017 |
BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells M Haddad-Weber, P Prager, M Kunz, L Seefried, F Jakob, MM Murray, ... Cytotherapy 12 (4), 505-513, 2010 | 112 | 2010 |
Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells A Liedert, L Wagner, L Seefried, R Ebert, F Jakob, A Ignatius Biochemical and biophysical research communications 394 (3), 755-759, 2010 | 108 | 2010 |
Monitoring guidance for patients with hypophosphatasia treated with asfotase alfa PS Kishnani, ET Rush, P Arundel, N Bishop, K Dahir, W Fraser, ... Molecular genetics and metabolism 122 (1-2), 4-17, 2017 | 105 | 2017 |
Diagnostic delay is common among patients with hypophosphatasia: initial findings from a longitudinal, prospective, global registry W Högler, C Langman, H Gomes da Silva, S Fang, A Linglart, K Ozono, ... BMC Musculoskeletal Disorders 20, 1-9, 2019 | 97 | 2019 |
Pulse treatment with zoledronic acid causes sustained commitment of bone marrow derived mesenchymal stem cells for osteogenic differentiation R Ebert, S Zeck, R Krug, J Meissner-Weigl, D Schneider, L Seefried, ... Bone 44 (5), 858-864, 2009 | 92 | 2009 |
Efficacy of anti-sclerostin monoclonal antibody BPS804 in adult patients with hypophosphatasia L Seefried, J Baumann, S Hemsley, C Hofmann, E Kunstmann, B Kiese, ... The Journal of clinical investigation 127 (6), 2148-2158, 2017 | 84 | 2017 |
Clinical aspects of hypophosphatasia: an update C Hofmann, HJ Girschick, B Mentrup, S Graser, L Seefried, J Liese, ... Clinical Reviews in Bone and Mineral Metabolism 11, 60-70, 2013 | 76 | 2013 |
Interdisciplinary management of FGF23-related phosphate wasting syndromes: a consensus statement on the evaluation, diagnosis and care of patients with X-linked hypophosphataemia A Trombetti, N Al-Daghri, ML Brandi, JB Cannata-Andía, E Cavalier, ... Nature Reviews Endocrinology 18 (6), 366-384, 2022 | 74 | 2022 |
FGF23 is a putative marker for bone healing and regeneration S Goebel, J Lienau, U Rammoser, L Seefried, KF Wintgens, J Seufert, ... Journal of orthopaedic research 27 (9), 1141-1146, 2009 | 60 | 2009 |
High prevalence of vitamin D deficiency in patients with bone marrow edema syndrome of the foot and ankle K Horas, L Fraissler, G Maier, F Jakob, L Seefried, C Konrads, M Rudert, ... Foot & ankle international 38 (7), 760-766, 2017 | 55 | 2017 |
Subtrochanteric and diaphyseal femoral fractures in hypophosphatasia—not atypical at all F Genest, L Seefried Osteoporosis international 29, 1815-1825, 2018 | 53 | 2018 |
Burden of disease associated with X-linked hypophosphataemia in adults: a systematic literature review L Seefried, M Smyth, R Keen, P Harvengt Osteoporosis International 32, 7-22, 2021 | 51 | 2021 |
Age and osteoporosis: effects of aging on osteoporosis, the diagnostics and therapy F Jakob, L Seefried, M Schwab Der Internist 55, 755-761, 2014 | 51 | 2014 |
Burden of illness in adults with hypophosphatasia: data from the global hypophosphatasia patient registry L Seefried, K Dahir, A Petryk, W Högler, A Linglart, GÁ Martos‐Moreno, ... Journal of Bone and Mineral Research 35 (11), 2171-2178, 2020 | 46 | 2020 |
Primary osteoporosis is not reflected by disease‐specific DNA methylation or accelerated epigenetic age in blood E Fernandez‐Rebollo, M Eipel, L Seefried, P Hoffmann, K Strathmann, ... Journal of Bone and Mineral Research 33 (2), 356-361, 2018 | 43 | 2018 |
Distribution of Constituents and Metabolites of Maritime Pine Bark Extract (Pycnogenol®) into Serum, Blood Cells, and Synovial Fluid of Patients with Severe … M Mülek, L Seefried, F Genest, P Högger Nutrients 9 (5), 443, 2017 | 43 | 2017 |
Challenges in the management of tumor-induced osteomalacia (TIO) ML Brandi, GPR Clunie, P Houillier, SMJ de Beur, S Minisola, R Oheim, ... Bone 152, 116064, 2021 | 42 | 2021 |
Pathophysiology of bone metabolism F Jakob, L Seefried, R Ebert Der Internist 49, 1159-1169, 2008 | 42 | 2008 |