An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units G Wong, A Brinkman, RJ Benefield, M Carlier, JJ De Waele, N El Helali, ... Journal of antimicrobial chemotherapy 69 (5), 1416-1423, 2014 | 249 | 2014 |
Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review FB Sime, MS Roberts, SL Peake, J Lipman, JA Roberts Annals of intensive care 2, 1-11, 2012 | 224 | 2012 |
Augmented renal clearance in critically ill patients: etiology, definition and implications for beta-lactam dose optimization FB Sime, AA Udy, JA Roberts Current opinion in pharmacology 24, 1-6, 2015 | 142 | 2015 |
What antibiotic exposures are required to suppress the emergence of resistance for gram-negative bacteria? A systematic review CD Sumi, AJ Heffernan, J Lipman, JA Roberts, FB Sime Clinical pharmacokinetics 58, 1407-1443, 2019 | 138 | 2019 |
How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients? G Wong, FB Sime, J Lipman, JA Roberts BMC infectious diseases 14, 1-11, 2014 | 133 | 2014 |
Solid nanoparticles for oral antimicrobial drug delivery: A review A Raza, FB Sime, PJ Cabot, F Maqbool, JA Roberts, JR Falconer Drug Discovery Today 24 (3), 858-866, 2019 | 109 | 2019 |
Optimization of dosing regimens and dosing in special populations FB Sime, MS Roberts, JA Roberts Clinical Microbiology and Infection 21 (10), 886-893, 2015 | 94 | 2015 |
The global prevalence of multidrug-resistance among Acinetobacter baumannii causing hospital-acquired and ventilator-associated pneumonia and its associated mortality: A … SMS Lim, AZ Abidin, SM Liew, JA Roberts, FB Sime Journal of infection 79 (6), 593-600, 2019 | 93 | 2019 |
Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies FB Sime, MS Roberts, JA Roberts, TA Robertson Journal of Chromatography B 960, 134-144, 2014 | 93 | 2014 |
Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial FB Sime, MS Roberts, IS Tiong, JH Gardner, S Lehman, SL Peake, ... Journal of Antimicrobial Chemotherapy 70 (8), 2369-2375, 2015 | 89 | 2015 |
Individualising therapy to minimize bacterial multidrug resistance AJ Heffernan, FB Sime, J Lipman, JA Roberts Drugs 78, 621-641, 2018 | 68 | 2018 |
Optimizing dosing of antibiotics in critically ill patients SL Parker, FB Sime, JA Roberts Current Opinion in Infectious Diseases 28 (6), 497-504, 2015 | 58 | 2015 |
Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by Gram-negative bacilli: a systematic review AJ Heffernan, FB Sime, J Lipman, J Dhanani, K Andrews, D Ellwood, ... International journal of antimicrobial agents 53 (3), 234-245, 2019 | 54 | 2019 |
Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy FB Sime, MS Roberts, MS Warner, U Hahn, TA Robertson, S Yeend, ... Antimicrobial agents and chemotherapy 58 (6), 3533-3537, 2014 | 45 | 2014 |
Population pharmacokinetics of unbound ceftolozane and tazobactam in critically ill patients without renal dysfunction FB Sime, M Lassig-Smith, T Starr, J Stuart, S Pandey, SL Parker, ... Antimicrobial agents and chemotherapy 63 (10), 10.1128/aac. 01265-19, 2019 | 41 | 2019 |
Oral meropenem for superbugs: challenges and opportunities A Raza, SC Ngieng, FB Sime, PJ Cabot, JA Roberts, A Popat, T Kumeria, ... Drug discovery today 26 (2), 551-560, 2021 | 34 | 2021 |
Pharmacodynamics of aerosolized fosfomycin and amikacin against resistant clinical isolates of Pseudomonas aeruginosa and Klebsiella pneumoniae in a hollow-fiber infection … FB Sime, A Johnson, S Whalley, A Santoyo-Castelazo, AB Montgomery, ... Antimicrobial agents and chemotherapy 61 (1), 10.1128/aac. 01763-16, 2017 | 32 | 2017 |
How to optimize antibiotic pharmacokinetic/pharmacodynamics for Gram-negative infections in critically ill patients AJ Heffernan, FB Sime, FS Taccone, JA Roberts Current Opinion in Infectious Diseases 31 (6), 555-565, 2018 | 31 | 2018 |
Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review F Paruk, FB Sime, J Lipman, JA Roberts International journal of antimicrobial agents 49 (4), 395-402, 2017 | 31 | 2017 |
Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies FB Sime, MS Roberts, IS Tiong, JH Gardner, S Lehman, SL Peake, ... Antimicrobial Agents and Chemotherapy 59 (9), 5463-5469, 2015 | 31 | 2015 |