DNA and RNA in anhydrous media: Duplex, triplex, and G‐quadruplex secondary structures in a deep eutectic solvent I Mamajanov, AE Engelhart, HD Bean, NV Hud Angewandte Chemie International Edition 49 (36), 6310-6314, 2010 | 226 | 2010 |
Nucleic acid-metal ion interactions NV Hud Royal Society of Chemistry, 2009 | 134* | 2009 |
Functional RNAs exhibit tolerance for non-heritable 2′–5′ versus 3′–5′ backbone heterogeneity AE Engelhart, MW Powner, JW Szostak Nature chemistry 5 (5), 390-394, 2013 | 125 | 2013 |
Ester formation and hydrolysis during wet–dry cycles: generation of far-from-equilibrium polymers in a model prebiotic reaction I Mamajanov, PJ MacDonald, J Ying, DM Duncanson, GR Dowdy, ... Macromolecules 47 (4), 1334-1343, 2014 | 122 | 2014 |
Primitive genetic polymers AE Engelhart, NV Hud Cold Spring Harbor Perspectives in Biology 2 (12), a002196, 2010 | 111 | 2010 |
A simple physical mechanism enables homeostasis in primitive cells AE Engelhart, KP Adamala, JW Szostak Nature chemistry 8 (5), 448-453, 2016 | 105 | 2016 |
Isothermal SARS-CoV-2 diagnostics: tools for enabling distributed pandemic testing as a means of supporting safe reopenings P Khan, LM Aufdembrink, AE Engelhart ACS Synthetic Biology 9 (11), 2861-2880, 2020 | 76 | 2020 |
Collaboration between primitive cell membranes and soluble catalysts KP Adamala, AE Engelhart, JW Szostak Nature communications 7 (1), 11041, 2016 | 74 | 2016 |
Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world ED Horowitz, AE Engelhart, MC Chen, KA Quarles, MW Smith, DG Lynn, ... Proceedings of the National Academy of Sciences 107 (12), 5288-5293, 2010 | 71 | 2010 |
Mars extant life: what's next? Conference report BL Carrier, DW Beaty, MA Meyer, JG Blank, L Chou, S DasSarma, ... Astrobiology 20 (6), 785-814, 2020 | 69 | 2020 |
Structural insights into the effects of 2′-5′ linkages on the RNA duplex J Sheng, L Li, AE Engelhart, J Gan, J Wang, JW Szostak Proceedings of the National Academy of Sciences 111 (8), 3050-3055, 2014 | 55 | 2014 |
Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites AG Tsai, AE Engelhart, MH Ma'mon, SI Houston, NV Hud, IS Haworth, ... Journal of biological chemistry 284 (11), 7157-7164, 2009 | 49 | 2009 |
Metal ion interactions with G-quadruplex structures AE Engelhart, J Plavec, Ö Persil, NV Hud | 42 | 2008 |
Submicromolar, Selective G‐Quadruplex Ligands from One Pot: Thermodynamic and Structural Studies of Human Telomeric DNA Binding by Azacyanines Ö Persil Çetinkol, AE Engelhart, RK Nanjunda, WD Wilson, NV Hud ChemBioChem 9 (12), 1889-1892, 2008 | 30 | 2008 |
Generation of functional RNAs from inactive oligonucleotide complexes by non-enzymatic primer extension K Adamala, AE Engelhart, JW Szostak Journal of the American Chemical Society 137 (1), 483-489, 2015 | 29 | 2015 |
Cold Spring Harbor Perspect AE Engelhart, NV Hud Biol 2, a002196, 2010 | 28 | 2010 |
Programmable fusion and differentiation of synthetic minimal cells NJ Gaut, J Gomez-Garcia, JM Heili, B Cash, Q Han, AE Engelhart, ... ACS Synthetic Biology 11 (2), 855-866, 2022 | 25 | 2022 |
Preparation, purification, and use of fatty acid-containing liposomes L Jin, AE Engelhart, KP Adamala, JW Szostak JoVE (Journal of Visualized Experiments), e57324, 2018 | 24 | 2018 |
Catalysis of template-directed nonenzymatic RNA copying by Iron (II) L Jin, AE Engelhart, W Zhang, K Adamala, JW Szostak Journal of the American Chemical Society 140 (44), 15016-15021, 2018 | 20 | 2018 |
Construction of a liposome dialyzer for the preparation of high-value, small-volume liposome formulations K Adamala, AE Engelhart, NP Kamat, L Jin, JW Szostak Nature protocols 10 (6), 927-938, 2015 | 20 | 2015 |