Reconciled rat and human metabolic networks for comparative toxicogenomics and biomarker predictions EM Blais, KD Rawls, BV Dougherty, ZI Li, GL Kolling, P Ye, A Wallqvist, ... Nature communications 8 (1), 14250, 2017 | 168 | 2017 |
Transcriptome-guided parsimonious flux analysis improves predictions with metabolic networks in complex environments ML Jenior, TJ Moutinho Jr, BV Dougherty, JA Papin PLoS computational biology 16 (4), e1007099, 2020 | 56 | 2020 |
A simplified metabolic network reconstruction to promote understanding and development of flux balance analysis tools KD Rawls, BV Dougherty, EM Blais, E Stancliffe, GL Kolling, K Vinnakota, ... Computers in Biology and Medicine 105, 64-71, 2019 | 27 | 2019 |
Validation of genomic and transcriptomic models of homologous recombination deficiency in a real-world pan-cancer cohort BD Leibowitz, BV Dougherty, JSK Bell, J Kapilivsky, J Michuda, ... BMC cancer 22 (1), 587, 2022 | 26 | 2022 |
Miniaturized plate readers for low-cost, high-throughput phenotypic screening PA Jensen, BV Dougherty, TJ Moutinho Jr, JA Papin Journal of laboratory automation 20 (1), 51-55, 2015 | 20 | 2015 |
Identifying functional metabolic shifts in heart failure with the integration of omics data and a heart-specific, genome-scale model BV Dougherty, KD Rawls, GL Kolling, KC Vinnakota, A Wallqvist, ... Cell Reports 34 (10), 2021 | 17 | 2021 |
Genome-scale characterization of toxicity-induced metabolic alterations in primary hepatocytes KD Rawls, EM Blais, BV Dougherty, KC Vinnakota, VR Pannala, ... Toxicological Sciences 172 (2), 279-291, 2019 | 17 | 2019 |
Metabolomics as a truly translational tool for precision medicine JC Schmidt, BV Dougherty, RD Beger, DP Jones, MA Schmidt, WB Mattes International journal of toxicology 40 (5), 413-426, 2021 | 13 | 2021 |
Predicting changes in renal metabolism after compound exposure with a genome-scale metabolic model KD Rawls, BV Dougherty, KC Vinnakota, VR Pannala, A Wallqvist, ... Toxicology and applied pharmacology 412, 115390, 2021 | 11 | 2021 |
Accelerating the Drug Development Pipeline with Genome‐Scale Metabolic Network Reconstructions BV Dougherty, TJ Moutinho Jr, J Papin Systems Biology 6, 139-162, 2017 | 10 | 2017 |
Systems biology approaches help to facilitate interpretation of cross-species comparisons BV Dougherty, JA Papin Current Opinion in Toxicology 23, 74-79, 2020 | 6 | 2020 |
Method suction device and related method thereof JP Riordan, BV Dougherty, RM Foley, J Kanwal, AM Guendel US Patent 9,993,585, 2018 | 6 | 2018 |
Metabolic network reconstructions to predict drug targets and off-target effects K Rawls, BV Dougherty, J Papin Metabolic Flux Analysis in Eukaryotic Cells: Methods and Protocols, 315-330, 2020 | 3 | 2020 |
Identifying metabolic adaptations characteristic of cardiotoxicity using paired transcriptomics and metabolomics data integrated with a computational model of heart metabolism BV Dougherty, CJ Moore, KD Rawls, ML Jenior, B Chun, S Nagdas, ... PLOS Computational Biology 20 (2), e1011919, 2024 | | 2024 |
Systems and Methods for Detecting Cellular Pathway Dysregulation in Cancer Specimens J Drews, B Dougherty, L Langer, C Igartua, AJ Sedgwick, J Guinney US Patent App. 18/176,476, 2023 | | 2023 |
Temporal concordance rates of pathogenic variants in liquid biopsies taken after solid tissue NGS profiling in a real-world pan-cancer cohort M MacKay, J Drews, BV Dougherty, D Hassane, C Mason, G Khullar, ... Cancer Research 82 (12_Supplement), 62-62, 2022 | | 2022 |
Identifying metabolic adaptations during cardiotoxicity using paired transcriptomics and metabolomics data integrated with a model of heart metabolism BV Dougherty, KD Rawls, ML Jenior, B Chun, S Nagdas, JJ Saucerman, ... bioRxiv, 2021.10. 31.466544, 2021 | | 2021 |
Optical density system and related method thereof JA Papin, BV Dougherty, AM Geldert, KP Seitter US Patent 10,907,122, 2021 | | 2021 |
Genome-Scale Characterization of Toxicity-Induced Metabolic Alterations in Primary KD Rawls, EM Blais, BV Dougherty, KC Vinnakota, VR Pannala, ... Nat Biotechnol 34 (5), 525-527, 2019 | | 2019 |