Metabolic signature of extracellular vesicles depends on the cell culture conditions M Palviainen, H Saari, O Kärkkäinen, J Pekkinen, S Auriola, M Yliperttula, ... Journal of extracellular vesicles 8 (1), 1596669, 2019 | 124 | 2019 |
Microbiota-derived metabolites as drivers of gut–brain communication H Ahmed, Q Leyrolle, V Koistinen, O Kärkkäinen, S Layé, N Delzenne, ... Gut microbes 14 (1), 2102878, 2022 | 95 | 2022 |
“Notame”: workflow for non-targeted LC–MS metabolic profiling A Klåvus, M Kokla, S Noerman, VM Koistinen, M Tuomainen, I Zarei, ... Metabolites 10 (4), 135, 2020 | 85 | 2020 |
Contribution of gut microbiota to metabolism of dietary glycine betaine in mice and in vitro colonic fermentation VM Koistinen, O Kärkkäinen, K Borewicz, I Zarei, J Jokkala, V Micard, ... Microbiome 7, 1-14, 2019 | 84 | 2019 |
Diets rich in whole grains increase betainized compounds associated with glucose metabolism O Kärkkäinen, MA Lankinen, M Vitale, J Jokkala, J Leppänen, V Koistinen, ... The American journal of clinical nutrition 108 (5), 971-979, 2018 | 52 | 2018 |
Maternal microbiota-derived metabolic profile in fetal murine intestine, brain and placenta T Pessa-Morikawa, A Husso, O Kärkkäinen, V Koistinen, K Hanhineva, ... BMC microbiology 22 (1), 46, 2022 | 45 | 2022 |
Heart specific PGC-1α deletion identifies metabolome of cardiac restricted metabolic heart failure O Kärkkäinen, T Tuomainen, M Mutikainen, M Lehtonen, JL Ruas, ... Cardiovascular research 115 (1), 107-118, 2019 | 43 | 2019 |
Specific gut microbial, biological, and psychiatric profiling related to binge eating disorders: a cross-sectional study in obese patients Q Leyrolle, R Cserjesi, MDGH Mulders, G Zamariola, S Hiel, ... Clinical nutrition 40 (4), 2035-2044, 2021 | 41 | 2021 |
HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage S Loppi, N Kolosowska, O Kärkkäinen, P Korhonen, M Huuskonen, ... Brain, behavior, and immunity 73, 670-681, 2018 | 38 | 2018 |
mGluR1/5 receptor densities in the brains of alcoholic subjects: a whole-hemisphere autoradiography study J Kupila, O Kärkkäinen, V Laukkanen, E Tupala, J Tiihonen, M Storvik Psychiatry Research: Neuroimaging 212 (3), 245-250, 2013 | 30 | 2013 |
Quantitative assessment of betainized compounds and associations with dietary and metabolic biomarkers in the randomized study of the healthy Nordic diet (SYSDIET) M Tuomainen, O Kärkkäinen, J Leppänen, S Auriola, M Lehtonen, ... The American journal of clinical nutrition 110 (5), 1108-1118, 2019 | 29 | 2019 |
Changes in the human metabolome associated with alcohol use: A review T Voutilainen, O Kärkkäinen Alcohol and Alcoholism 54 (3), 225-234, 2019 | 29 | 2019 |
A non-targeted LC-MS profiling reveals elevated levels of carnitine precursors and trimethylated compounds in the cord plasma of pre-eclamptic infants T Jääskeläinen, O Kärkkäinen, J Jokkala, K Litonius, S Heinonen, ... Scientific reports 8 (1), 14616, 2018 | 28 | 2018 |
Whole grain intake associated molecule 5-aminovaleric acid betaine decreases β-oxidation of fatty acids in mouse cardiomyocytes O Kärkkäinen, T Tuomainen, V Koistinen, M Tuomainen, J Leppänen, ... Scientific reports 8 (1), 13036, 2018 | 28 | 2018 |
Diet-and microbiota-related metabolite, 5-aminovaleric acid betaine (5-AVAB), in health and disease R Haikonen, O Kärkkäinen, V Koistinen, K Hanhineva Trends in Endocrinology & Metabolism 33 (7), 463-480, 2022 | 26 | 2022 |
Metabolic profiling of high egg consumption and the associated lower risk of type 2 diabetes in middle‐aged finnish men S Noerman, O Kärkkäinen, A Mattsson, J Paananen, M Lehtonen, T Nurmi, ... Molecular nutrition & food research 63 (5), 1800605, 2019 | 26 | 2019 |
AMPA receptors in post-mortem brains of Cloninger type 1 and 2 alcoholics: a whole-hemisphere autoradiography study O Kärkkäinen, J Kupila, M Häkkinen, V Laukkanen, E Tupala, ... Psychiatry Research: Neuroimaging 214 (3), 429-434, 2013 | 22 | 2013 |
Metabolome of canine and human saliva: a non-targeted metabolomics study S Turunen, J Puurunen, S Auriola, AM Kullaa, O Kärkkäinen, H Lohi, ... Metabolomics 16, 1-12, 2020 | 21 | 2020 |
A non-targeted LC–MS metabolic profiling of pregnancy: longitudinal evidence from healthy and pre-eclamptic pregnancies T Jääskeläinen, O Kärkkäinen, J Jokkala, A Klåvus, S Heinonen, ... Metabolomics 17, 1-12, 2021 | 20 | 2021 |
Decreased serum total cholesterol is associated with a history of childhood physical violence in depressed outpatients SL Kraav, T Tolmunen, O Kärkkäinen, A Ruusunen, H Viinamäki, ... Psychiatry research 272, 326-333, 2019 | 20 | 2019 |