AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-β peptide metabolism V Vingtdeux, L Giliberto, H Zhao, P Chandakkar, Q Wu, JE Simon, ... Journal of Biological Chemistry 285 (12), 9100-9113, 2010 | 714 | 2010 |
Oxidative stress activates a positive feedback between the γ‐and β‐secretase cleavages of the β‐amyloid precursor protein E Tamagno, M Guglielmotto, M Aragno, R Borghi, R Autelli, L Giliberto, ... Journal of neurochemistry 104 (3), 683-695, 2008 | 415 | 2008 |
The up‐regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α M Guglielmotto, M Aragno, R Autelli, L Giliberto, E Novo, S Colombatto, ... Journal of neurochemistry 108 (4), 1045-1056, 2009 | 274 | 2009 |
β-amyloid is different in normal aging and in Alzheimer disease A Piccini, C Russo, A Gliozzi, A Relini, A Vitali, R Borghi, L Giliberto, ... Journal of Biological Chemistry 280 (40), 34186-34192, 2005 | 234 | 2005 |
Hemorrhagic posterior reversible encephalopathy syndrome as a manifestation of COVID-19 infection AM Franceschi, O Ahmed, L Giliberto, M Castillo American Journal of Neuroradiology 41 (7), 1173-1176, 2020 | 185 | 2020 |
The familial dementia BRI2 gene binds the Alzheimer gene amyloid-β precursor protein and inhibits amyloid-β production S Matsuda, L Giliberto, Y Matsuda, P Davies, E McGowan, F Pickford, ... Journal of Biological Chemistry 280 (32), 28912-28916, 2005 | 168 | 2005 |
Plasma levels of amyloid β-protein 42 are increased in women with mild cognitive impairment A Assini, S Cammarata, A Vitali, M Colucci, L Giliberto, R Borghi, ... Neurology 63 (5), 828-831, 2004 | 168 | 2004 |
Oxidative stress mediates the pathogenic effect of different Alzheimer's disease risk factors M Guglielmotto, L Giliberto, E Tamagno, M Tabaton Frontiers in aging neuroscience 2, 1276, 2010 | 165 | 2010 |
BRI2 inhibits amyloid β-peptide precursor protein processing by interfering with the docking of secretases to the substrate S Matsuda, L Giliberto, Y Matsuda, EM McGowan, L D'Adamio Journal of Neuroscience 28 (35), 8668-8676, 2008 | 113 | 2008 |
Signaling effect of amyloid-β42 on the processing of AβPP M Tabaton, X Zhu, G Perry, MA Smith, L Giliberto Experimental neurology 221 (1), 18-25, 2010 | 102 | 2010 |
JNK and ERK1/2 pathways have a dual opposite effect on the expression of BACE1 E Tamagno, M Guglielmotto, L Giliberto, A Vitali, R Borghi, R Autelli, ... Neurobiology of aging 30 (10), 1563-1573, 2009 | 86 | 2009 |
Tyr682 in the Intracellular Domain of APP Regulates Amyloidogenic APP Processing In Vivo APM Barbagallo, R Weldon, R Tamayev, D Zhou, L Giliberto, O Foreman, ... PloS one 5 (11), e15503, 2010 | 82 | 2010 |
Mutant presenilin 1 increases the expression and activity of BACE1 L Giliberto, R Borghi, A Piccini, R Mangerini, S Sorbi, G Cirmena, A Garuti, ... Journal of Biological Chemistry 284 (14), 9027-9038, 2009 | 76 | 2009 |
CD36 overexpression in human brain correlates with β-amyloid deposition but not with Alzheimer's disease R Ricciarelli, C d'Abramo, JM Zingg, L Giliberto, W Markesbery, A Azzi, ... Free Radical Biology and Medicine 36 (8), 1018-1024, 2004 | 68 | 2004 |
Aβ1‐42‐mediated down‐regulation of Uch‐L1 is dependent on NF‐κB activation and impaired BACE1 lysosomal degradation M Guglielmotto, D Monteleone, M Boido, A Piras, L Giliberto, R Borghi, ... Aging cell 11 (5), 834-844, 2012 | 67 | 2012 |
Amyloid-β 42 activates the expression of BACE1 through the JNK pathway M Guglielmotto, D Monteleone, L Giliberto, M Fornaro, R Borghi, ... Journal of Alzheimer's Disease 27 (4), 871-883, 2011 | 67 | 2011 |
Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a" regulated" transcriptional role L Giliberto, D Zhou, R Weldon, E Tamagno, P De Luca, M Tabaton, ... Molecular neurodegeneration 3, 1-12, 2008 | 67 | 2008 |
Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis R Tamayev, L Giliberto, W Li, C d'Abramo, O Arancio, R Vidal, L D'Adamio Journal of Neuroscience 30 (44), 14915-14924, 2010 | 64 | 2010 |
APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant R Tamayev, S Matsuda, L Giliberto, O Arancio, L D'adamio The EMBO journal 30 (12), 2501-2509, 2011 | 60 | 2011 |
Significance of blood and cerebrospinal fluid biomarkers for Alzheimer’s disease: sensitivity, specificity and potential for clinical use C d’Abramo, L D’adamio, L Giliberto Journal of Personalized Medicine 10 (3), 116, 2020 | 51 | 2020 |