| Coumarins as modulators of the Keap1/Nrf2/ARE signaling pathway EHM Hassanein, AM Sayed, OE Hussein, AM Mahmoud Oxidative Medicine and Cellular Longevity 2020 (1), 1675957, 2020 | 165 | 2020 |
| The impact of Keap1/Nrf2, P38MAPK/NF-κB and Bax/Bcl2/caspase-3 signaling pathways in the protective effects of berberine against methotrexate-induced nephrotoxicity EHM Hassanein, AGS Shalkami, MM Khalaf, WR Mohamed, ... Biomedicine & Pharmacotherapy 109, 47-56, 2019 | 90 | 2019 |
| New 1, 2, 4-triazole/pyrazole hybrids linked to oxime moiety as nitric oxide donor celecoxib analogs: Synthesis, cyclooxygenase inhibition anti-inflammatory, ulcerogenicity … WAA Fadaly, YAMM Elshaier, EHM Hassanein, KRA Abdellatif Bioorganic Chemistry 98, 103752, 2020 | 65 | 2020 |
| Renoprotective effects of umbelliferone on methotrexate-induced renal injury through regulation of Nrf-2/Keap-1, P38MAPK/NF-κB, and apoptosis signaling pathways EHM Hassanein, WR Mohamed, AGS Shalkami, MM Khalaf, ... Food and chemical toxicology 116, 152-160, 2018 | 60 | 2018 |
| Coenzyme Q10 protects hepatocytes from ischemia reperfusion-induced apoptosis and oxidative stress via regulation of Bax/Bcl-2/PUMA and Nrf-2/FOXO-3/Sirt-1 signaling pathways AR Mahmoud, FEM Ali, TH Abd-Elhamid, EHM Hassanein Tissue and Cell 60, 1-13, 2019 | 50 | 2019 |
| Flavonoids-mediated SIRT1 signaling activation in hepatic disorders AM Sayed, EHM Hassanein, SH Salem, OE Hussein, AM Mahmoud Life sciences 259, 118173, 2020 | 42 | 2020 |
| Reno-protective effects of ursodeoxycholic acid against gentamicin-induced nephrotoxicity through modulation of NF-κB, eNOS and caspase-3 expressions TH Abd-Elhamid, DA Elgamal, SS Ali, FEM Ali, EHM Hassanein, ... Cell and tissue research 374, 367-387, 2018 | 39 | 2018 |
| Umbelliferone attenuates gentamicin-induced renal toxicity by suppression of TLR-4/NF-κB-p65/NLRP-3 and JAK1/STAT-3 signaling pathways EHM Hassanein, FEM Ali, MR Kozman, OAM Abd El-Ghafar Environmental Science and Pollution Research 28, 11558-11571, 2021 | 38 | 2021 |
| Rebamipide potentially mitigates methotrexate‐induced nephrotoxicity via inhibition of oxidative stress and inflammation: A molecular and histochemical study RA Elmansy, HS Seleem, AR Mahmoud, EHM Hassanein, FEM Ali The Anatomical Record 304 (3), 647-661, 2021 | 38 | 2021 |
| Edaravone and acetovanillone upregulate Nrf2 and PI3K/Akt/mTOR signaling and prevent cyclophosphamide cardiotoxicity in rats EHM Hassanein, OAM Abd El-Ghafar, MA Ahmed, AM Sayed, ... Drug Design, Development and Therapy, 5275-5288, 2020 | 37 | 2020 |
| Ursodeoxycholic acid abrogates gentamicin-induced hepatotoxicity in rats: Role of NF-κB-p65/TNF-α, Bax/Bcl-xl/Caspase-3, and eNOS/iNOS pathways FEM Ali, EHM Hassanein, AG Bakr, EAM El-Shoura, DA El-Gamal, ... Life sciences 254, 117760, 2020 | 36 | 2020 |
| Nephroprotective effect of umbelliferone against cisplatin‐induced kidney damage is mediated by regulation of NRF2, cytoglobin, SIRT1/FOXO‐3, and NF‐ kB‐p65 … FEM Ali, EHM Hassanein, AH El‐Bahrawy, ZMM Omar, EK Rashwan, ... Journal of Biochemical and Molecular Toxicology 35 (5), e22738, 2021 | 34 | 2021 |
| Hepatoprotective effect of rebamipide against methotrexate-induced hepatic intoxication: role of Nrf2/GSK-3β, NF-κβ-p65/JAK1/STAT3, and PUMA/Bax/Bcl-2 signaling pathways BA Abdel-Wahab, FEM Ali, SA Alkahtani, AM Alshabi, MH Mahnashi, ... Immunopharmacology and Immunotoxicology 42 (5), 493-503, 2020 | 32 | 2020 |
| Agomelatine prevents gentamicin nephrotoxicity by attenuating oxidative stress and TLR-4 signaling, and upregulating PPARγ and SIRT1 AM Mahmoud, OAM Abd El-Ghafar, MA Alzoghaibi, EHM Hassanein Life Sciences 278, 119600, 2021 | 31 | 2021 |
| Roflumilast protects from cisplatin-induced testicular toxicity in male rats and enhances its cytotoxicity in prostate cancer cell line. Role of NF-κB-p65, cAMP/PKA and Nrf2/HO … BA Abdel-Wahab, IA Walbi, HA Albarqi, FEM Ali, EHM Hassanein Food and Chemical Toxicology 151, 112133, 2021 | 31 | 2021 |
| Targeting KEAP1/Nrf2, AKT, and PPAR-γ signals as a potential protective mechanism of diosmin against gentamicin-induced nephrotoxicity FEM Ali, AM Sayed, AH El-Bahrawy, ZMM Omar, EHM Hassanein Life Sciences 275, 119349, 2021 | 30 | 2021 |
| Perindopril Ameliorates Hepatic Ischemia Reperfusion Injury Via Regulation of NF‐κB‐p65/TLR‐4, JAK1/STAT‐3, Nrf‐2, and PI3K/Akt/mTOR Signaling Pathways EO Kamel, EHM Hassanein, MA Ahmed, FEM Ali The Anatomical Record 303 (7), 1935-1949, 2020 | 29 | 2020 |
| Farnesol attenuates oxidative stress and liver injury and modulates fatty acid synthase and acetyl-CoA carboxylase in high cholesterol-fed rats MH Abukhalil, OE Hussein, M Bin-Jumah, SAM Saghir, MO Germoush, ... Environmental Science and Pollution Research 27, 30118-30132, 2020 | 28 | 2020 |
| Optimization of pyrazole-based compounds with 1, 2, 4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase … KRA Abdellatif, EKA Abdelall, HAH Elshemy, JN Philoppes, ... Bioorganic chemistry 114, 105122, 2021 | 27 | 2021 |
| 7-hydroxycoumarin modulates Nrf2/HO-1 and microRNA-34a/SIRT1 signaling and prevents cisplatin-induced oxidative stress, inflammation, and kidney injury in rats DH Sami, AS Soliman, AA Khowailed, EHM Hassanein, EM Kamel, ... Life Sciences 310, 121104, 2022 | 26 | 2022 |
Fares E.M. AliPhD, Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar university在 Azhar.edu.eg 的电子邮件经过验证
