| CTCF boundary remodels chromatin domain and drives aberrant HOX gene transcription in acute myeloid leukemia H Luo, F Wang, J Zha, H Li, B Yan, Q Du, F Yang, A Sobh, C Vulpe, ... Blood, The Journal of the American Society of Hematology 132 (8), 837-848, 2018 | 65 | 2018 |
| Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL–Specific Degrader DT2216 D Thummuri, S Khan, PW Underwood, P Zhang, J Wiegand, X Zhang, ... Molecular cancer therapeutics 21 (1), 184-192, 2022 | 39 | 2022 |
| Piperlongumine conjugates induce targeted protein degradation J Pei, Y Xiao, X Liu, W Hu, A Sobh, Y Yuan, S Zhou, N Hua, ... Cell chemical biology 30 (2), 203-213. e17, 2023 | 38* | 2023 |
| Genome-scale CRISPR screens identify host factors that promote human coronavirus infection M Grodzki, AP Bluhm, M Schaefer, A Tagmount, M Russo, A Sobh, ... Genome medicine 14 (1), 10, 2022 | 35 | 2022 |
| Functional profiling identifies determinants of arsenic trioxide cellular toxicity A Sobh, A Loguinov, GN Yazici, RS Zeidan, A Tagmount, NS Hejazi, ... Toxicological Sciences 169 (1), 108-121, 2019 | 29 | 2019 |
| Separation and characterization of endogenous nucleosomes by native capillary zone electrophoresis–top-down mass spectrometry K Jooß, LF Schachner, R Watson, ZB Gillespie, SA Howard, MA Cheek, ... Analytical chemistry 93 (12), 5151-5160, 2021 | 22 | 2021 |
| Discovery of a potent and selective targeted NSD2 degrader for the reduction of H3K36me2 RP Hanley, DY Nie, JR Tabor, F Li, A Sobh, C Xu, NK Barker, D Dilworth, ... Journal of the American Chemical Society 145 (14), 8176-8188, 2023 | 20 | 2023 |
| Applying genome-wide CRISPR to identify known and novel genes and pathways that modulate formaldehyde toxicity Y Zhao, L Wei, A Tagmount, A Loguinov, A Sobh, A Hubbard, CM McHale, ... Chemosphere 269, 128701, 2021 | 19 | 2021 |
| Genome-Wide CRISPR Screening Identifies the Tumor Suppressor Candidate OVCA2 As a Determinant of Tolerance to Acetaldehyde A Sobh, A Loguinov, A Stornetta, S Balbo, A Tagmount, L Zhang, ... Toxicological Sciences 169 (1), 235-245, 2019 | 17 | 2019 |
| Functional pathway identification with CRISPR/Cas9 genome-wide gene disruption in human dopaminergic neuronal cells following chronic treatment with dieldrin M Russo, A Sobh, P Zhang, A Loguinov, A Tagmount, CD Vulpe, B Liu Toxicological Sciences 176 (2), 366-381, 2020 | 15 | 2020 |
| Genetic screens reveal CCDC115 as a modulator of erythroid iron and heme trafficking A Sobh, A Loguinov, J Zhou, S Jenkitkasemwong, R Zeidan, ... American journal of hematology 95 (9), 1085-1098, 2020 | 13 | 2020 |
| Treatment with HIV-protease inhibitor nelfinavir identifies membrane lipid composition and fluidity as a therapeutic target in advanced multiple myeloma L Besse, A Besse, SC Stolze, A Sobh, EA Zaal, AJ van der Ham, M Ruiz, ... Cancer research 81 (17), 4581-4593, 2021 | 11 | 2021 |
| Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer P Gupta, K Strange, R Telange, A Guo, H Hatch, A Sobh, J Elie, AM Carter, ... Cell reports 40 (7), 2022 | 10 | 2022 |
| CXL146, a novel 4H-chromene derivative, targets GRP78 to selectively eliminate multidrug-resistant cancer cells T Bian, A Tagmount, A Sobh, C Vulpe, KC Vijendra, C Xing Molecular Pharmacology 97 (6), 402-408, 2020 | 10 | 2020 |
| Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML NHK Nguyen, R Rafiee, A Tagmount, A Sobh, A Loguinov, ... Blood Advances 7 (9), 1769-1783, 2023 | 9 | 2023 |
| CRISPR genomic screening informs gene–environment interactions A Sobh, C Vulpe Current Opinion in Toxicology 18, 46-53, 2019 | 7 | 2019 |
| CRISPR Screens in toxicology research: an overview A Sobh, M Russo, CD Vulpe Current protocols 1 (5), e136, 2021 | 6 | 2021 |
| Genome-scale CRISPR-Cas9 synthetic lethal screening of AML cell line identified functional modulators of etoposide resistance predictive of clinical outcome in AML patients R Rafiee, A Sobh, AH Elsayed, A Tagmount, CD Vulpe, JK Lamba Blood 134, 2685, 2019 | 5 | 2019 |
| HOX loci focused CRISPR/sgRNA library screening identifying critical CTCF boundaries H Luo, A Sobh, CD Vulpe, E Brewer, S Dovat, Y Qiu, S Huang JoVE (Journal of Visualized Experiments), e59382, 2019 | 4 | 2019 |
| Identification of Genetic Vulnerabilities and Synthetic-Lethal Targets in NSD2-High Multiple Myeloma A Sobh, C Kaestner, A Riva, JD Licht Blood 134, 3757, 2019 | 2 | 2019 |
