Microenvironment drug resistance in multiple myeloma: emerging new players L Di Marzo, V Desantis, AG Solimando, S Ruggieri, T Annese, B Nico, ... Oncotarget 7 (37), 60698, 2016 | 167 | 2016 |
Bone marrow fibroblasts overexpress miR‐27b and miR‐214 in step with multiple myeloma progression, dependent on tumour cell‐derived exosomes MA Frassanito, V Desantis, L Di Marzo, I Craparotta, L Beltrame, ... The Journal of pathology 247 (2), 241-253, 2019 | 89 | 2019 |
Mechanisms of resistance to anti-CD38 daratumumab in multiple myeloma I Saltarella, V Desantis, A Melaccio, AG Solimando, A Lamanuzzi, R Ria, ... Cells 9 (1), 167, 2020 | 87 | 2020 |
Halting pro-survival autophagy by TGFβ inhibition in bone marrow fibroblasts overcomes bortezomib resistance in multiple myeloma patients MA Frassanito, K De Veirman, V Desantis, L Di Marzo, D Vergara, ... Leukemia 30 (3), 640-648, 2016 | 79 | 2016 |
Autophagy: a new mechanism of prosurvival and drug resistance in multiple myeloma V Desantis, I Saltarella, A Lamanuzzi, MA Mariggiò, V Racanelli, A Vacca, ... Translational oncology 11 (6), 1350-1357, 2018 | 78 | 2018 |
JAM-A as a prognostic factor and new therapeutic target in multiple myeloma AG Solimando, A Brandl, K Mattenheimer, C Graf, M Ritz, A Ruckdeschel, ... Leukemia 32 (3), 736-743, 2018 | 73 | 2018 |
High-risk multiple myeloma: integrated clinical and omics approach dissects the neoplastic clone and the tumor microenvironment AG Solimando, MC Da Vià, S Cicco, P Leone, G Di Lernia, D Giannico, ... Journal of clinical medicine 8 (7), 997, 2019 | 59 | 2019 |
Inhibition of mTOR complex 2 restrains tumor angiogenesis in multiple myeloma A Lamanuzzi, I Saltarella, V Desantis, MA Frassanito, P Leone, ... Oncotarget 9 (29), 20563, 2018 | 54 | 2018 |
Targeting angiogenesis in multiple myeloma by the VEGF and HGF blocking DARPin® protein MP0250: A preclinical study L Rao, K De Veirman, D Giannico, I Saltarella, V Desantis, MA Frassanito, ... Oncotarget 9 (17), 13366, 2018 | 50 | 2018 |
MicroRNAs-based nano-strategies as new therapeutic approach in multiple myeloma to overcome disease progression and drug resistance V Desantis, I Saltarella, A Lamanuzzi, A Melaccio, AG Solimando, ... International journal of molecular sciences 21 (9), 3084, 2020 | 48 | 2020 |
FGF trapping inhibits multiple myeloma growth through c-Myc degradation–induced mitochondrial oxidative stress R Ronca, GC Ghedini, F Maccarinelli, A Sacco, SL Locatelli, E Foglio, ... Cancer research 80 (11), 2340-2354, 2020 | 43 | 2020 |
Diabetes and Alzheimer’s disease: might mitochondrial dysfunction help deciphering the common path? MA Potenza, L Sgarra, V Desantis, C Nacci, M Montagnani Antioxidants 10 (8), 1257, 2021 | 39 | 2021 |
Homotypic and Heterotypic Activation of the Notch Pathway in Multiple Myeloma–Enhanced Angiogenesis: A Novel Therapeutic Target? I Saltarella, MA Frassanito, A Lamanuzzi, A Brevi, P Leone, V Desantis, ... Neoplasia 21 (1), 93-105, 2019 | 32 | 2019 |
Myeloma cells act as tolerogenic antigen‐presenting cells and induce regulatory T cells in vitro MA Frassanito, S Ruggieri, V Desantis, L Di Marzo, P Leone, V Racanelli, ... European journal of haematology 95 (1), 65-74, 2015 | 25 | 2015 |
Belimumab restores Treg/Th17 balance in patients with refractory systemic lupus erythematosus M Prete, P Leone, MA Frassanito, V Desantis, C Marasco, S Cicco, ... Lupus 27 (12), 1926-1935, 2018 | 21 | 2018 |
Isolation and characterization of neural stem cells from dystrophic mdx mouse T Annese, P Corsi, S Ruggieri, R Tamma, C Marinaccio, S Picocci, ... Experimental Cell Research 343 (2), 190-207, 2016 | 21 | 2016 |
The leading role of the immune microenvironment in multiple myeloma: A new target with a great prognostic and clinical value V Desantis, FD Savino, A Scaringella, MA Potenza, C Nacci, ... Journal of Clinical Medicine 11 (9), 2513, 2022 | 20 | 2022 |
Mast cells and interleukins AG Solimando, V Desantis, D Ribatti International Journal of Molecular Sciences 23 (22), 14004, 2022 | 18 | 2022 |
Role of extracellular vesicle-based cell-to-cell communication in multiple myeloma progression I Saltarella, A Lamanuzzi, B Apollonio, V Desantis, G Bartoli, A Vacca, ... Cells 10 (11), 3185, 2021 | 18 | 2021 |
Rhu-Epo down-regulates pro-tumorigenic activity of cancer-associated fibroblasts in multiple myeloma V Desantis, MA Frassanito, R Tamma, I Saltarella, L Di Marzo, ... Annals of Hematology 97, 1251-1258, 2018 | 18 | 2018 |