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| Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma F Pene, YE Claessens, O Muller, F Viguie, P Mayeux, F Dreyfus, ... Oncogene 21 (43), 6587-6597, 2002 | 444 | 2002 |
| Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition N Jacque, AM Ronchetti, C Larrue, G Meunier, R Birsen, L Willems, ... Blood, The Journal of the American Society of Hematology 126 (11), 1346-1356, 2015 | 379 | 2015 |
| Role of the PI3K/AKT and mTOR signaling pathways in acute myeloid leukemia S Park, N Chapuis, J Tamburini, V Bardet, P Cornillet-Lefebvre, L Willems, ... haematologica 95 (5), 819, 2010 | 362 | 2010 |
| Essential role for the p110δ isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia P Sujobert, V Bardet, P Cornillet-Lefebvre, JS Hayflick, N Prie, F Verdier, ... Blood 106 (3), 1063-1066, 2005 | 348 | 2005 |
| Biology of erythropoietin C Lacombe, P Mayeux Haematologica 83 (8), 724-732, 1998 | 336 | 1998 |
| Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia L Willems, N Jacque, A Jacquel, N Neveux, T Trovati Maciel, M Lambert, ... Blood, The Journal of the American Society of Hematology 122 (20), 3521-3532, 2013 | 325 | 2013 |
| Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid … J Tamburini, N Chapuis, V Bardet, S Park, P Sujobert, L Willems, N Ifrah, ... Blood, The Journal of the American Society of Hematology 111 (1), 379-382, 2008 | 321 | 2008 |
| Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation: possible involvement of the ubiquitinated Cis protein F Verdier, S Chrétien, O Muller, P Varlet, A Yoshimura, S Gisselbrecht, ... Journal of Biological Chemistry 273 (43), 28185-28190, 1998 | 248 | 1998 |
| Identification of tyrosine residues within the intracellular domain of the erythropoietin receptor crucial for STAT5 activation. S Gobert, S Chretien, F Gouilleux, O Muller, C Pallard, I Dusanter‐Fourt, ... The EMBO journal 15 (10), 2434-2441, 1996 | 247 | 1996 |
| The molecular biology of erythropoietin. C Lacombe, P Mayeux Nephrology, dialysis, transplantation: official publication of the European …, 1999 | 245 | 1999 |
| PI-103, a dual inhibitor of Class IA phosphatidylinositide 3-kinase and mTOR, has antileukemic activity in AML S Park, N Chapuis, V Bardet, J Tamburini, N Gallay, L Willems, ZA Knight, ... Leukemia 22 (9), 1698-1706, 2008 | 243 | 2008 |
| Autoantibodies against erythropoietin in a patient with pure red-cell aplasia N Casadevall, E Dupuy, P Molho-Sabatier, G Tobelem, B Varet, P Mayeux New England Journal of Medicine 334 (10), 630-633, 1996 | 243 | 1996 |
| PI3K and mTOR signaling pathways in cancer: new data on targeted therapies L Willems, J Tamburini, N Chapuis, C Lacombe, P Mayeux, D Bouscary Current oncology reports 14, 129-138, 2012 | 241 | 2012 |
| The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation AS Green, N Chapuis, T Trovati Maciel, L Willems, M Lambert, C Arnoult, ... Blood, The Journal of the American Society of Hematology 116 (20), 4262-4273, 2010 | 239 | 2010 |
| Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia J Tamburini, AS Green, V Bardet, N Chapuis, S Park, L Willems, ... Blood, The Journal of the American Society of Hematology 114 (8), 1618-1627, 2009 | 230 | 2009 |
| Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation D Bouscary, F Pene, YE Claessens, O Muller, S Chrétien, ... Blood, The Journal of the American Society of Hematology 101 (9), 3436-3443, 2003 | 222 | 2003 |
| Both proteasomes and lysosomes degrade the activated erythropoietin receptor P Walrafen, F Verdier, Z Kadri, S Chrétien, C Lacombe, P Mayeux Blood 105 (2), 600-608, 2005 | 217 | 2005 |
| High levels of CD34+ CD38low/− CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia: a Groupe Ouest-Est des Leucemies Aigues et Maladies du Sang … F Vergez, AS Green, J Tamburini, JE Sarry, B Gaillard, ... haematologica 96 (12), 1792, 2011 | 216 | 2011 |
| Comprehensive proteomic analysis of human erythropoiesis EF Gautier, S Ducamp, M Leduc, V Salnot, F Guillonneau, M Dussiot, ... Cell reports 16 (5), 1470-1484, 2016 | 213 | 2016 |
