Synthesis, crystallization, and biological evaluation of an orally active prodrug of gemcitabine DM Bender, J Bao, AH Dantzig, WD Diseroad, KL Law, NA Magnus, ... Journal of medicinal chemistry 52 (22), 6958-6961, 2009 | 127 | 2009 |
Mitsunobu approach to the synthesis of optically active α, α-disubstituted amino acids JE Green, DM Bender, S Jackson, MJ O’Donnell, JR McCarthy Organic Letters 11 (4), 807-810, 2009 | 98 | 2009 |
Characterization of the expression and activity of carboxylesterases 1 and 2 from the beagle dog, cynomolgus monkey, and human ET Williams, JA Bacon, DM Bender, JJ Lowinger, WK Guo, ME Ehsani, ... Drug metabolism and disposition 39 (12), 2305-2313, 2011 | 73 | 2011 |
Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1 … J Hao, JP Beck, JM Schaus, JH Krushinski, Q Chen, CD Beadle, P Vidal, ... Journal of Medicinal Chemistry 62 (19), 8711-8732, 2019 | 50 | 2019 |
Amide, carbamate, and urea derivatives MB Arnold, DM Bender, TJ Bleisch, WD Jones, PL Ornstein, ... US Patent 6,617,351, 2003 | 47 | 2003 |
Cyclopropanecarboxylic acid esters as potential prodrugs with enhanced hydrolytic stability DM Bender, JA Peterson, JR McCarthy, H Gunaydin, Y Takano, KN Houk Organic Letters 10 (3), 509-511, 2008 | 44 | 2008 |
An efficient synthesis of (S)-m-tyrosine DM Bender, RM Williams The Journal of Organic Chemistry 62 (19), 6690-6691, 1997 | 38 | 1997 |
Clomiphene analogs with activity in vitro and in vivo against human breast cancer cells RJ Baumann, TL Bush, DE Cross-Doersen, EA Cashman, PS Wright, ... Biochemical Pharmacology 55 (6), 841-851, 1998 | 30 | 1998 |
mGlu2/3 agonist-induced hyperthermia: an in vivo assay for detection of mGlu2/3 receptor antagonism and its relation to antidepressant-like efficacy in mice SD Gleason, X Li, IA Smith, JD Ephlin, XS Wang, BA Heinz, JH Carter, ... CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2013 | 29 | 2013 |
Pyrrolidine derivatives useful as BACE inhibitors TA Shepherd, IR Garcia US Patent 7,585,885, 2009 | 25 | 2009 |
Pharmacokinetic and screening studies of the interaction between mononuclear phagocyte system and nanoparticle formulations and colloid forming drugs AT Lucas, LB Herity, ZA Kornblum, AJ Madden, A Gabizon, AV Kabanov, ... International Journal of Pharmaceutics 526 (1-2), 443-454, 2017 | 19 | 2017 |
Discovery formulations: approaches and practices in early preclinical development SN Bhattachar, DM Bender, SA Sweetana, JA Wesley Discovering and developing molecules with optimal drug-like properties, 49-94, 2015 | 19 | 2015 |
Clinical bioavailability of the novel BACE1 inhibitor lanabecestat (AZD3293): assessment of tablet formulations versus an oral solution and the impact of gastric pH on … N Ye, SA Monk, P Daga, DM Bender, LB Rosen, J Mullen, MC Minkwitz, ... Clinical Pharmacology in Drug Development 7 (3), 233-243, 2018 | 16 | 2018 |
Facile rearrangement of N4-(α-aminoacyl) cytidines to N-(4-cytidinyl) amino acid amides D Zhang, DM Bender, F Victor, JA Peterson, RD Boyer, GA Stephenson, ... Tetrahedron Letters 49 (13), 2052-2055, 2008 | 14 | 2008 |
An Efficient Palladium-Catalysed Aminocarbonylation of Benzyl Chlorides E Rilvin-Derrick, N Oram, J Richardson Synlett 31 (04), 369-372, 2020 | 9 | 2020 |
Sulphonamide derivatives MB Arnold, DM Bender, AH Fray, WD Jones, PL Ornstein, RL Simon, ... US Patent 6,358,981, 2002 | 8 | 2002 |
Clinical considerations for infant heel blood sampling. AR Fleischman, LC Borris, D Bender, D Matthews Neonatal Intensive Care: the Journal of Perinatology-neonatology 5 (3), 62-68, 1992 | 7 | 1992 |
Translating molecules into medicines SN Bhattachar, JS Morrison, DR Mudra, DM Bender Springer, 2017 | 6 | 2017 |
Heterocyclic sulfonamide derivatives D Bender, S Forman, W Jones, D Smith, H Zarrinmayeh, D Zimmerman US Patent App. 10/343,186, 2003 | 6 | 2003 |
An Efficient Palladium-Catalyzed α-Arylation of Acetone Below its Boiling Point J Richardson, SP Mutton, FM Martin, L Walton, AJ Ledgard Synlett 31 (15), 1532-1536, 2020 | 5 | 2020 |