Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors S Doulatov, LT Vo, SS Chou, PG Kim, N Arora, H Li, BK Hadland, ... Cell stem cell 13 (4), 459-470, 2013 | 321 | 2013 |
A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development BK Hadland, SS Huppert, J Kanungo, Y Xue, R Jiang, T Gridley, ... Blood 104 (10), 3097-3105, 2004 | 301 | 2004 |
γ-Secretase inhibitors repress thymocyte development BK Hadland, NR Manley, D Su, GD Longmore, CL Moore, MS Wolfe, ... Proceedings of the National Academy of Sciences 98 (13), 7487-7491, 2001 | 266 | 2001 |
Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells NJ Palpant, L Pabon, CE Friedman, M Roberts, B Hadland, ... Nature protocols 12 (1), 15-31, 2017 | 199 | 2017 |
Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE M Vooijs, CT Ong, B Hadland, S Huppert, Z Liu, J Korving, ... Oxford University Press for The Company of Biologists Limited 134 (3), 535-544, 2007 | 168 | 2007 |
A MOLECULAR PHYLOGENETIC ANALYSIS OF REPRODUCTIVE TRAIT EVOLUTION IN THE SOFT CORAL GENUS ALCYONIUM CS McFadden, R Donahue, BK Hadland, R Weston Evolution 55 (1), 54-67, 2001 | 113 | 2001 |
NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells GI Uenishi, HS Jung, A Kumar, MA Park, BK Hadland, E McLeod, ... Nature communications 9 (1), 1828, 2018 | 108 | 2018 |
Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros–derived hematopoietic stem cells BK Hadland, B Varnum-Finney, MG Poulos, RT Moon, JM Butler, S Rafii, ... The Journal of clinical investigation 125 (5), 2032-2045, 2015 | 97 | 2015 |
Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes NJ Palpant, L Pabon, M Roberts, B Hadland, D Jones, C Jones, RT Moon, ... Development 142 (18), 3198-3209, 2015 | 79 | 2015 |
Erythroid-stimulating agents in cancer therapy: potential dangers and biologic mechanisms BK Hadland, GD Longmore Journal of clinical oncology 27 (25), 4217-4226, 2009 | 75 | 2009 |
Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development NJ Palpant, L Pabon, JS Rabinowitz, BK Hadland, CL Stoick-Cooper, ... Development 140 (18), 3799-3808, 2013 | 68 | 2013 |
3D curvature-instructed endothelial flow response and tissue vascularization C Mandrycky, B Hadland, Y Zheng Science advances 6 (38), eabb3629, 2020 | 61 | 2020 |
Notch pathway is dispensable for adipocyte specification AM Nichols, Y Pan, A Herreman, BK Hadland, B De Strooper, R Kopan, ... Genesis 40 (1), 40-44, 2004 | 58 | 2004 |
Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo T Dignum, B Varnum-Finney, SR Srivatsan, S Dozono, O Waltner, ... Cell reports 36 (11), 2021 | 56 | 2021 |
A common origin for B-1a and B-2 lymphocytes in clonal pre-hematopoietic stem cells BK Hadland, B Varnum-Finney, PK Mandal, DJ Rossi, MG Poulos, ... Stem cell reports 8 (6), 1563-1572, 2017 | 56 | 2017 |
Many layers of embryonic hematopoiesis: new insights into B-cell ontogeny and the origin of hematopoietic stem cells B Hadland, M Yoshimoto Experimental hematology 60, 1-9, 2018 | 46 | 2018 |
Chromatin and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a regulator of primitive hematopoiesis NJ Palpant, Y Wang, B Hadland, RJ Zaunbrecher, M Redd, D Jones, ... Cell reports 20 (7), 1597-1608, 2017 | 39 | 2017 |
Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics B Hadland, B Varnum-Finney, S Dozono, T Dignum, C Nourigat-McKay, ... Nature communications 13 (1), 1584, 2022 | 34 | 2022 |
Engineered murine HSCs reconstitute multi-lineage hematopoiesis and adaptive immunity YF Lu, P Cahan, S Ross, J Sahalie, PM Sousa, BK Hadland, W Cai, ... Cell reports 17 (12), 3178-3192, 2016 | 31 | 2016 |
Maturation of hematopoietic stem cells from prehematopoietic stem cells is accompanied by up-regulation of PD-L1 J Tober, MMW Maijenburg, Y Li, L Gao, BK Hadland, P Gao, K Minoura, ... Journal of Experimental Medicine 215 (2), 645-659, 2018 | 23 | 2018 |