Oxytocin by intranasal and intravenous routes reaches the cerebrospinal fluid in rhesus macaques: determination using a novel oxytocin assay MR Lee, KB Scheidweiler, XX Diao, F Akhlaghi, A Cummins, MA Huestis, ... Molecular psychiatry 23 (1), 115-122, 2018 | 238 | 2018 |
New synthetic cannabinoids metabolism and strategies to best identify optimal marker metabolites X Diao, MA Huestis Frontiers in chemistry 7, 109, 2019 | 133 | 2019 |
Metabolism and pharmacokinetics of 3-n-butylphthalide (NBP) in humans: the role of cytochrome P450s and alcohol dehydrogenase in biotransformation X Diao, P Deng, C Xie, X Li, D Zhong, Y Zhang, X Chen Drug Metabolism and Disposition 41 (2), 430-444, 2013 | 120 | 2013 |
Approaches, challenges, and advances in metabolism of new synthetic cannabinoids and identification of optimal urinary marker metabolites X Diao, MA Huestis Clinical Pharmacology & Therapeutics 101 (2), 239-253, 2017 | 112 | 2017 |
High-resolution mass spectrometry for characterizing the metabolism of synthetic cannabinoid THJ-018 and its 5-fluoro analog THJ-2201 after incubation in human hepatocytes X Diao, A Wohlfarth, S Pang, KB Scheidweiler, MA Huestis Clinical chemistry 62 (1), 157-169, 2016 | 85 | 2016 |
Metabolism and bioactivation of famitinib, a novel inhibitor of receptor tyrosine kinase, in cancer patients C Xie, J Zhou, Z Guo, X Diao, Z Gao, D Zhong, H Jiang, L Zhang, X Chen British Journal of Pharmacology 168 (7), 1687-1706, 2013 | 83 | 2013 |
Metabolic profiling of new synthetic cannabinoids AMB and 5F‐AMB by human hepatocyte and liver microsome incubations and high‐resolution mass spectrometry M Andersson, X Diao, A Wohlfarth, KB Scheidweiler, MA Huestis Rapid Communications in Mass Spectrometry 30 (8), 1067-1078, 2016 | 77 | 2016 |
Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry Y Zhu, L Li, G Zhang, H Wan, C Yang, X Diao, X Chen, L Zhang, D Zhong Journal of Chromatography B 1033, 117-127, 2016 | 75 | 2016 |
In Vitro and In Vivo Human Metabolism of Synthetic Cannabinoids FDU-PB-22 and FUB-PB-22 X Diao, KB Scheidweiler, A Wohlfarth, S Pang, R Kronstrand, MA Huestis The AAPS journal 18, 455-464, 2016 | 70 | 2016 |
In vitro metabolite profiling of ADB-FUBINACA, a new synthetic cannabinoid J Carlier, X Diao, A Wohlfarth, K Scheidweiler, M A Huestis Current neuropharmacology 15 (5), 682-691, 2017 | 60 | 2017 |
25C‐NBOMe and 25I‐NBOMe metabolite studies in human hepatocytes, in vivo mouse and human urine with high‐resolution mass spectrometry A Wohlfarth, M Roman, M Andersson, FC Kugelberg, X Diao, J Carlier, ... Drug testing and analysis 9 (5), 680-698, 2017 | 59 | 2017 |
4-Methoxy-α-PVP: in silico prediction, metabolic stability, and metabolite identification by human hepatocyte incubation and high-resolution mass spectrometry KN Ellefsen, A Wohlfarth, MJ Swortwood, X Diao, M Concheiro, ... Forensic toxicology 34, 61-75, 2016 | 58 | 2016 |
In Vitro, in Vivo and In Silico Metabolic Profiling of α-Pyrrolidinopentiothiophenone, A Novel Thiophene Stimulant MJ Swortwood, J Carlier, KN Ellefsen, A Wohlfarth, X Diao, ... Bioanalysis 8 (1), 65-82, 2016 | 56 | 2016 |
Bioactivation of 3-n-butylphthalide via sulfation of its major metabolite 3-hydroxy-NBP: mediated mainly by sulfotransferase 1A1 X Diao, X Pang, C Xie, Z Guo, D Zhong, X Chen Drug Metabolism and Disposition 42 (4), 774-781, 2014 | 56 | 2014 |
Distinguishing intake of new synthetic cannabinoids ADB-PINACA and 5F-ADB-PINACA with human hepatocyte metabolites and high-resolution mass spectrometry J Carlier, X Diao, KB Scheidweiler, MA Huestis Clinical Chemistry 63 (5), 1008-1021, 2017 | 55 | 2017 |
Simultaneous quantitation of 3-n-butylphthalide (NBP) and its four major metabolites in human plasma by LC–MS/MS using deuterated internal standards X Diao, Z Ma, H Wang, D Zhong, Y Zhang, J Jin, Y Fan, X Chen Journal of Pharmaceutical and Biomedical Analysis 78, 19-26, 2013 | 55 | 2013 |
In vitro and in vivo human metabolism of a new synthetic cannabinoid NM-2201 (CBL-2201) X Diao, J Carlier, M Zhu, S Pang, R Kronstrand, KB Scheidweiler, ... Forensic toxicology 35, 20-32, 2017 | 45 | 2017 |
First metabolic profile of PV8, a novel synthetic cathinone, in human hepatocytes and urine by high-resolution mass spectrometry MJ Swortwood, KN Ellefsen, A Wohlfarth, X Diao, M Concheiro-Guisan, ... Analytical and bioanalytical chemistry 408, 4845-4856, 2016 | 43 | 2016 |
Metabolism and pharmacokinetics of morinidazole in humans: identification of diastereoisomeric morpholine N+-glucuronides catalyzed by UDP glucuronosyltransferase 1A9 R Gao, L Li, C Xie, X Diao, D Zhong, X Chen Drug Metabolism and Disposition 40 (3), 556-567, 2012 | 37 | 2012 |
Strategies to distinguish new synthetic cannabinoid FUBIMINA (BIM-2201) intake from its isomer THJ-2201: metabolism of FUBIMINA in human hepatocytes X Diao, KB Scheidweiler, A Wohlfarth, M Zhu, S Pang, MA Huestis Forensic toxicology 34, 256-267, 2016 | 33 | 2016 |