关注
Yuko Tsutsui
Yuko Tsutsui
Yale Cancer Biology Institute
在 yale.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Hydrogen/deuterium exchange-mass spectrometry: a powerful tool for probing protein structure, dynamics and interactions
Y Tsutsui, PL Wintrode
Current medicinal chemistry 14 (22), 2344-2358, 2007
1422007
Folding mechanism of the metastable serpin α1-antitrypsin
Y Tsutsui, RD Cruz, PL Wintrode
Proceedings of the National Academy of Sciences 109 (12), 4467-4472, 2012
752012
The conformational dynamics of a metastable serpin studied by hydrogen exchange and mass spectrometry
Y Tsutsui, L Liu, A Gershenson, PL Wintrode
Biochemistry 45 (21), 6561-6569, 2006
602006
Structural insights into pseudokinase domains of receptor tyrosine kinases
JB Sheetz, S Mathea, H Karvonen, K Malhotra, D Chatterjee, W Niininen, ...
Molecular cell 79 (3), 390-405. e7, 2020
562020
The structural basis of serpin polymerization studied by hydrogen/deuterium exchange and mass spectrometry
Y Tsutsui, B Kuri, T Sengupta, PL Wintrode
Journal of Biological Chemistry 283 (45), 30804-30811, 2008
412008
Crystal structures of β-1, 4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding
Y Tsutsui, B Ramakrishnan, PK Qasba
Journal of Biological Chemistry 288 (44), 31963-31970, 2013
382013
Cooperative unfolding of a metastable serpin to a molten globule suggests a link between functional and folding energy landscapes
Y Tsutsui, PL Wintrode
Journal of molecular biology 371 (1), 245-255, 2007
242007
Local and global effects of a cavity filling mutation in a metastable serpin
T Sengupta, Y Tsutsui, PL Wintrode
Biochemistry 48 (34), 8233, 2009
202009
Structural basis for ligand reception by anaplastic lymphoma kinase
T Li, SE Stayrook, Y Tsutsui, J Zhang, Y Wang, H Li, A Proffitt, SG Krimmer, ...
Nature 600 (7887), 148-152, 2021
182021
Imatinib binding to human c-Src is coupled to inter-domain allostery and suggests a novel kinase inhibition strategy
Y Tsutsui, D Deredge, PL Wintrode, FA Hays
Scientific Reports 6, 2016
122016
Overproduction and biophysical characterization of human HSP70 proteins
RC Boswell-Casteel, JM Johnson, KD Duggan, Y Tsutsui, FA Hays
Protein expression and purification 106, 57-65, 2015
122015
Probing serpin conformational change using mass spectrometry and related methods.
Y Tsutsui, A Sarkar, PL Wintrode
Methods in enzymology 501, 325, 2011
72011
Conformation-Dependent Human p52Shc Phosphorylation by Human c-Src
Y Tsutsui, JM Johnson, B Demeler, MT Kinter, FA Hays
Biochemistry 54 (22), 3469-3482, 2015
52015
A Link Between Alzheimer's and Type II Diabetes Mellitus? Ca+2‐Mediated Signal Control and Protein Localization
Y Tsutsui, FA Hays
BioEssays 40 (6), 1700219, 2018
42018
Biochemical and structural basis for differential inhibitor sensitivity of EGFR with distinct exon 19 mutations
IK van Alderwerelt van Rosenburgh, DM Lu, MJ Grant, SE Stayrook, ...
Nature Communications 13 (1), 6791, 2022
12022
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