Hydrogen/deuterium exchange-mass spectrometry: a powerful tool for probing protein structure, dynamics and interactions Y Tsutsui, PL Wintrode Current medicinal chemistry 14 (22), 2344-2358, 2007 | 142 | 2007 |
Folding mechanism of the metastable serpin α1-antitrypsin Y Tsutsui, RD Cruz, PL Wintrode Proceedings of the National Academy of Sciences 109 (12), 4467-4472, 2012 | 75 | 2012 |
The conformational dynamics of a metastable serpin studied by hydrogen exchange and mass spectrometry Y Tsutsui, L Liu, A Gershenson, PL Wintrode Biochemistry 45 (21), 6561-6569, 2006 | 60 | 2006 |
Structural insights into pseudokinase domains of receptor tyrosine kinases JB Sheetz, S Mathea, H Karvonen, K Malhotra, D Chatterjee, W Niininen, ... Molecular cell 79 (3), 390-405. e7, 2020 | 56 | 2020 |
The structural basis of serpin polymerization studied by hydrogen/deuterium exchange and mass spectrometry Y Tsutsui, B Kuri, T Sengupta, PL Wintrode Journal of Biological Chemistry 283 (45), 30804-30811, 2008 | 41 | 2008 |
Crystal structures of β-1, 4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding Y Tsutsui, B Ramakrishnan, PK Qasba Journal of Biological Chemistry 288 (44), 31963-31970, 2013 | 38 | 2013 |
Cooperative unfolding of a metastable serpin to a molten globule suggests a link between functional and folding energy landscapes Y Tsutsui, PL Wintrode Journal of molecular biology 371 (1), 245-255, 2007 | 24 | 2007 |
Local and global effects of a cavity filling mutation in a metastable serpin T Sengupta, Y Tsutsui, PL Wintrode Biochemistry 48 (34), 8233, 2009 | 20 | 2009 |
Structural basis for ligand reception by anaplastic lymphoma kinase T Li, SE Stayrook, Y Tsutsui, J Zhang, Y Wang, H Li, A Proffitt, SG Krimmer, ... Nature 600 (7887), 148-152, 2021 | 18 | 2021 |
Imatinib binding to human c-Src is coupled to inter-domain allostery and suggests a novel kinase inhibition strategy Y Tsutsui, D Deredge, PL Wintrode, FA Hays Scientific Reports 6, 2016 | 12 | 2016 |
Overproduction and biophysical characterization of human HSP70 proteins RC Boswell-Casteel, JM Johnson, KD Duggan, Y Tsutsui, FA Hays Protein expression and purification 106, 57-65, 2015 | 12 | 2015 |
Probing serpin conformational change using mass spectrometry and related methods. Y Tsutsui, A Sarkar, PL Wintrode Methods in enzymology 501, 325, 2011 | 7 | 2011 |
Conformation-Dependent Human p52Shc Phosphorylation by Human c-Src Y Tsutsui, JM Johnson, B Demeler, MT Kinter, FA Hays Biochemistry 54 (22), 3469-3482, 2015 | 5 | 2015 |
A Link Between Alzheimer's and Type II Diabetes Mellitus? Ca+2‐Mediated Signal Control and Protein Localization Y Tsutsui, FA Hays BioEssays 40 (6), 1700219, 2018 | 4 | 2018 |
Biochemical and structural basis for differential inhibitor sensitivity of EGFR with distinct exon 19 mutations IK van Alderwerelt van Rosenburgh, DM Lu, MJ Grant, SE Stayrook, ... Nature Communications 13 (1), 6791, 2022 | 1 | 2022 |