关注
Alexandra Schnell
Alexandra Schnell
Whitehead Institute and MIT
在 wi.mit.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
T helper cell cytokines modulate intestinal stem cell renewal and differentiation
M Biton*, AL Haber*, N Rogel*, G Burgin, S Beyaz, A Schnell, ...
Cell 175 (5), 1307-1320. e22, 2018
4722018
Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors
S Haas, J Hansson, D Klimmeck, D Loeffler, L Velten, H Uckelmann, ...
Cell stem cell 17 (4), 422-434, 2015
4412015
Metabolic modeling of single Th17 cells reveals regulators of autoimmunity
A Wagner*, C Wang*, J Fessler, D DeTomaso, J Avila-Pacheco, ...
Cell 184 (16), 4168-4185. e21, 2021
2502021
The yin and yang of co-inhibitory receptors: toward anti-tumor immunity without autoimmunity
A Schnell, L Bod, A Madi, VK Kuchroo
Cell research 30 (4), 285-299, 2020
1802020
Calcitonin gene-related peptide negatively regulates alarmin-driven type 2 innate lymphoid cell responses
A Wallrapp*, PR Burkett*, SJ Riesenfeld*, SJ Kim, E Christian, ...
Immunity 51 (4), 709-723. e6, 2019
1562019
Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes
E Kiner, E Willie, B Vijaykumar, K Chowdhary, H Schmutz, J Chandler, ...
Nature immunology 22 (2), 216-228, 2021
1442021
Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity
A Schnell*, L Huang*, M Singer*, A Singaraju, RM Barilla, BML Regan, ...
Cell 184 (26), 6281-6298. e23, 2021
1222021
Combinatorial prediction of marker panels from single‐cell transcriptomic data
C Delaney*, A Schnell*, LV Cammarata*, A Yao‐Smith, A Regev, ...
Molecular systems biology 15 (10), e9005, 2019
752019
Developmental and cellular age direct conversion of CD4+ T cells into RORγ+ or Helios+ colon Treg cells
A Pratama, A Schnell, D Mathis, C Benoist
Journal of Experimental Medicine 217 (1), 2020
672020
An IL-27-driven transcriptional network identifies regulators of IL-10 expression across T helper cell subsets
H Zhang*, A Madi*, N Yosef, N Chihara, A Awasthi, C Pot, C Lambden, ...
Cell reports 33 (8), 2020
642020
Fas promotes T helper 17 cell differentiation and inhibits T helper 1 cell development by binding and sequestering transcription factor STAT1
GM Zu Horste, D Przybylski, MA Schramm, C Wang, A Schnell, Y Lee, ...
Immunity 48 (3), 556-569. e7, 2018
592018
Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function
D He, H Xu, H Zhang, R Tang, Y Lan, R Xing, S Li, E Christian, Y Hou, ...
Immunity 55 (1), 159-173. e9, 2022
582022
TH17 cell heterogeneity and its role in tissue inflammation
A Schnell, DR Littman, VK Kuchroo
Nature immunology 24 (1), 19-29, 2023
562023
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
P Hernández-Malmierca*, D Vonficht*, A Schnell*, HJ Uckelmann, ...
Cell Stem Cell 29 (5), 760-775. e10, 2022
412022
B-cell-specific checkpoint molecules that regulate anti-tumour immunity
L Bod, YC Kye, J Shi, E Torlai Triglia, A Schnell, J Fessler, SM Ostrowski, ...
Nature 619 (7969), 348-356, 2023
372023
Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4
H Uckelmann, S Blaszkiewicz, C Nicolae, S Haas, A Schnell, S Wurzer, ...
Journal of experimental medicine 213 (10), 1961-1971, 2016
342016
Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
J Duan*, JD Matute*, LW Unger, T Hanley, A Schnell, X Lin, N Krupka, ...
Immunity 56 (5), 1115-1131. e9, 2023
222023
Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling
M Pawlak*, D DeTomaso*, A Schnell, GM Zu Horste, Y Lee, J Nyman, ...
Immunity 55 (9), 1663-1679. e6, 2022
192022
Deciphering cell states and genealogies of human hematopoiesis
C Weng, F Yu, D Yang, M Poeschla, LA Liggett, MG Jones, X Qiu, ...
Nature 627, 389–398, 2024
132024
The chromatin landscape of Th17 cells reveals mechanisms of diversification of regulatory and pro-inflammatory states
PI Thakore*, A Schnell*, M Zhao, L Huang, Y Hou, E Christian, ...
BioRxiv, 2022.02. 26.482041, 2022
82022
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