Simulation of the clinical and pathological manifestations of coronavirus disease 2019 (COVID-19) in a golden Syrian hamster model: implications for disease pathogenesis and … JFW Chan, AJ Zhang, S Yuan, VKM Poon, CCS Chan, ACY Lee, ... Clinical infectious diseases 71 (9), 2428-2446, 2020 | 1210 | 2020 |
Surgical mask partition reduces the risk of noncontact transmission in a golden Syrian hamster model for coronavirus disease 2019 (COVID-19) JFW Chan, S Yuan, AJ Zhang, VKM Poon, CCS Chan, ACY Lee, Z Fan, ... Clinical infectious diseases 71 (16), 2139-2149, 2020 | 292 | 2020 |
Clofazimine broadly inhibits coronaviruses including SARS-CoV-2 S Yuan, X Yin, X Meng, JFW Chan, ZW Ye, L Riva, L Pache, CCY Chan, ... Nature 593 (7859), 418-423, 2021 | 186 | 2021 |
Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters S Yuan, ZW Ye, R Liang, K Tang, AJ Zhang, G Lu, CP Ong, VK Man Poon, ... Science 377 (6604), 428-433, 2022 | 136 | 2022 |
Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system S Yuan, JFW Chan, KKH Chik, CCY Chan, JOL Tsang, R Liang, J Cao, ... Pharmacological research 159, 104960, 2020 | 77 | 2020 |
Broad-spectrum host-based antivirals targeting the interferon and lipogenesis pathways as potential treatment options for the pandemic coronavirus disease 2019 (COVID-19) S Yuan, CCY Chan, KKH Chik, JOL Tsang, R Liang, J Cao, K Tang, ... Viruses 12 (6), 628, 2020 | 63 | 2020 |
Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection ZW Ye, S Yuan, JFW Chan, AJ Zhang, CY Yu, CP Ong, D Yang, ... Emerging microbes & infections 10 (1), 291-304, 2021 | 57 | 2021 |
Development of highly potent noncovalent inhibitors of SARS-CoV-2 3CLpro N Hou, L Shuai, L Zhang, X Xie, K Tang, Y Zhu, Y Yu, W Zhang, Q Tan, ... ACS central science 9 (2), 217-227, 2023 | 38 | 2023 |
SARS-CoV-2 exploits host DGAT and ADRP for efficient replication S Yuan, B Yan, J Cao, ZW Ye, R Liang, K Tang, C Luo, J Cai, H Chu, ... Cell Discovery 7 (1), 100, 2021 | 35 | 2021 |
Intranasal administration of a single dose of a candidate live attenuated vaccine derived from an NSP16-deficient SARS-CoV-2 strain confers sterilizing immunity in animals ZW Ye, CP Ong, K Tang, Y Fan, C Luo, R Zhou, P Luo, Y Cheng, VS Gray, ... Cellular & molecular immunology 19 (5), 588-601, 2022 | 30 | 2022 |
Targeting papain-like protease for broad-spectrum coronavirus inhibition S Yuan, X Gao, K Tang, JP Cai, M Hu, P Luo, L Wen, ZW Ye, C Luo, ... Protein & Cell 13 (12), 940-953, 2022 | 28 | 2022 |
Impact of Pb on Chlamydomonas reinhardtii at Physiological and Transcriptional Levels C Zheng, M Aslam, X Liu, H Du, X Xie, H Jia, N Huang, K Tang, Y Yang, ... Frontiers in Microbiology 11, 1443, 2020 | 27 | 2020 |
Comparative analysis of SARS‐CoV‐2 Omicron BA. 2.12. 1 and BA. 5.2 variants CP Ong, ZW Ye, K Tang, R Liang, Y Xie, H Zhang, Z Qin, H Sun, TY Wang, ... Journal of Medical Virology 95 (1), e28326, 2023 | 23 | 2023 |
Effect of different adjuvants on immune responses elicited by protein-based subunit vaccines against SARS-CoV-2 and its delta variant N Zhang, Q Ji, Z Liu, K Tang, Y Xie, K Li, J Zhou, S Li, H Shang, Z Shi, ... Viruses 14 (3), 501, 2022 | 22 | 2022 |
The SARS-CoV-2 Omicron (B. 1.1. 529) variant exhibits altered pathogenicity, transmissibility, and fitness in the golden Syrian hamster model S Yuan, ZW Ye, R Liang, K Tang, AJ Zhang, G Lu, CP Ong, VKM Poon, ... BioRxiv, 2022.01. 12.476031, 2022 | 22 | 2022 |
Inhaled Dry Powder Formulation of Tamibarotene, a Broad‐Spectrum Antiviral against Respiratory Viruses Including SARS‐CoV‐2 and Influenza Virus Q Liao, S Yuan, J Cao, K Tang, Y Qiu, HC Seow, RCH Man, Z Shao, ... Advanced Therapeutics 4 (7), 2100059, 2021 | 20 | 2021 |
Low environmental temperature exacerbates severe acute respiratory syndrome Coronavirus 2 infection in golden Syrian hamsters JFW Chan, VKM Poon, CCS Chan, KKH Chik, JOL Tsang, Z Zou, ... Clinical Infectious Diseases 75 (1), e1101-e1111, 2022 | 19 | 2022 |
Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters S Yuan, X Yin, XZ Meng, J Chan, ZW Ye, L Riva, L Pache, CCY Chan, ... Research square, 2020 | 18 | 2020 |
Human early syncytiotrophoblasts are highly susceptible to SARS-CoV-2 infection D Ruan, ZW Ye, S Yuan, Z Li, W Zhang, CP Ong, K Tang, TTKK Tam, ... Cell Reports Medicine 3 (12), 2022 | 15 | 2022 |
In silico structure-based discovery of a SARS-CoV-2 main protease inhibitor L Wen, K Tang, KKH Chik, CCY Chan, JOL Tsang, R Liang, J Cao, ... International Journal of Biological Sciences 17 (6), 1555, 2021 | 15 | 2021 |