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Katherine S. Bridge
Katherine S. Bridge
Kay Kendall Intermediate Fellow, Centre for Blood Research, University of York
在 york.ac.uk 的电子邮件经过验证 - 首页
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The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
DE Foxler, KS Bridge, V James, TM Webb, M Mee, SCK Wong, Y Feng, ...
Nature cell biology 14 (2), 201-208, 2012
1042012
Argonaute utilization for miRNA silencing is determined by phosphorylation-dependent recruitment of LIM-domain-containing proteins
KS Bridge, KM Shah, Y Li, DE Foxler, SCK Wong, DC Miller, KM Davidson, ...
Cell reports 20 (1), 173-187, 2017
672017
Identification of residues in ABCG2 affecting protein trafficking and drug transport, using co-evolutionary analysis of ABCG sequences
AJ Haider, MH Cox, N Jones, AJ Goode, KS Bridge, K Wong, D Briggs, ...
Bioscience reports 35 (4), e00241, 2015
312015
S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells
MJ Warner, KS Bridge, JP Hewitson, MR Hodgkinson, A Heyam, ...
Nucleic acids research 44 (20), 9942-9955, 2016
272016
A HIF–LIMD 1 negative feedback mechanism mitigates the pro‐tumorigenic effects of hypoxia
DE Foxler, KS Bridge, JG Foster, P Grevitt, S Curry, KM Shah, ...
EMBO molecular medicine 10 (8), e8304, 2018
212018
Hematopoietic stem cells retain functional potential and molecular identity in hibernation cultures
CA Oedekoven, M Belmonte, D Bode, FK Hamey, MS Shepherd, JLC Che, ...
Stem cell reports 16 (6), 1614-1628, 2021
172021
Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance-related vascular damage
A Maqbool, NT Watt, N Haywood, H Viswambharan, A Skromna, ...
American Journal of Physiology-Cell Physiology 319 (1), C64-C74, 2020
152020
Markers for human haematopoietic stem cells: The disconnect between an identification marker and its function
B Rix, AH Maduro, KS Bridge, W Grey
Frontiers in physiology 13, 1009160, 2022
122022
Physioxia improves the selectivity of hematopoietic stem cell expansion cultures
KJ Igarashi, I Kucinski, YY Chan, TK Tan, HM Khoo, D Kealy, J Bhadury, ...
Blood Advances 7 (14), 3366-3377, 2023
82023
Regulators of the hypoxic response: a growing family
KS Bridge, TV Sharp
Future Oncology 8 (5), 491-493, 2012
62012
The CKS1/CKS2 proteostasis Axis is crucial to maintain hematopoietic stem cell function
W Grey, S Atkinson, B Rix, P Casado, L Ariza-McNaughton, C Hawley, ...
Hemasphere 7 (3), e853, 2023
32023
Targeted therapy for LIMD1-deficient non-small cell lung cancer subtypes
K Davidson, P Grevitt, MF Contreras-Gerenas, KS Bridge, M Hermida, ...
Cell Death & Disease 12 (11), 1075, 2021
32021
ZMIZ1 enhances ERα-dependent expression of E2F2 in breast cancer
W Zhao, SF Rose, R Blake, A Godicelj, AE Cullen, J Stenning, L Beevors, ...
Journal of molecular endocrinology 73 (1), 2024
2024
PU. 1 Eviction at Lymphocyte-Specific Chromatin Domains Mediates Glucocorticoid Response in Acute Lymphoblastic Leukemia
D Jing, D Beck, H Cao, F Tian, Y Huang, H Zhao, X Tai, W XU, H Kosasih, ...
2024
Hypoxia-Inducible Factor-1 activated by PIM1 assembles a non-canonical transcription complex and resultant regulon that drives progression of JAK2V617F myeloproliferative neoplasms
D Kealy, R Ellerington, S Bansal, AGX Zeng, JJF Medeiros, KA West, ...
bioRxiv, 2024.07. 02.601518, 2024
2024
Aberrant Splicing of MBD1 Reshapes the Epigenome to Drive Convergent Myeloerythroid Defects in MDS
HTTT Chen, P Joshi, E Tsao, J Xu, S Jahangiri, Y Mo, D Kealy, ...
Blood 142, 317, 2023
2023
2018–UNRAVELLING THE EFFECTS OF THE JAK2 V617F MUTATION ON HIF-1 FUNCTION AT THE CHROMATIN
D Kealy, C Hawley, R Ellerington, B Ferreira, B Drylie, I Hitchcock, ...
Experimental Hematology 124, S45, 2023
2023
In Breast Cancer ZMIZ1 Co-Regulates E2F2 as Part of the Estrogen Receptor-Mediated Cell-Cycle Response
W Zhao, SF Rose, R Blake, A Godicelj, AE Cullen, J Stenning, L Beevors, ...
bioRxiv, 789610, 2019
2019
A HIF-LIMD1 negative feedback mechanism drives the adaptive response to hypoxia and mitigates pro-tumorigenic hypoxic effects
K Bridge, DE Foxler, JG Foster, P Grevitt, S Curry, KM Shah, KM Davidson, ...
EMBO Molecular Medicine, 2018
2018
Loss of LIM-domain proteins LIMD1, Ajuba and WTIP as a novel molecular mechanism for disease aetiology in clear cell renal cell carcinoma (ccRCC)
K Smith, M Sheaff, G Elia, A Clear, G Trevisan, D Foxler, K Bridge, ...
European Journal of Cancer 1 (61), S206, 2016
2016
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