| Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model E Spangenberg, PL Severson, LA Hohsfield, J Crapser, J Zhang, ... Nature communications 10 (1), 3758, 2019 | 614 | 2019 |
| Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice MRP Elmore, LA Hohsfield, EA Kramár, L Soreq, RJ Lee, ST Pham, ... Aging cell 17 (6), e12832, 2018 | 291 | 2018 |
| To kill a microglia: a case for CSF1R inhibitors KN Green, JD Crapser, LA Hohsfield Trends in immunology 41 (9), 771-784, 2020 | 177 | 2020 |
| Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain JD Crapser, EE Spangenberg, RA Barahona, MA Arreola, LA Hohsfield, ... EBioMedicine 58, 2020 | 162 | 2020 |
| Decreased Insulin-Receptor Signaling Promotes the Autophagic Degradation of β-Amyloid Peptide in C. elegans ML Florez-McClure, LA Hohsfield, G Fonte, MT Bealor, CD Link Autophagy 3 (6), 569-580, 2007 | 157 | 2007 |
| Migration of blood cells to β-amyloid plaques in Alzheimer's disease LA Hohsfield, C Humpel Experimental gerontology 65, 8-15, 2015 | 95 | 2015 |
| Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss MX Hernandez, S Jiang, TA Cole, SH Chu, MI Fonseca, MJ Fang, ... Molecular neurodegeneration 12, 1-19, 2017 | 73 | 2017 |
| Vascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models LA Hohsfield, N Daschil, G Orädd, I Strömberg, C Humpel Molecular and Cellular Neuroscience 63, 83-95, 2014 | 43 | 2014 |
| Microglial dyshomeostasis drives perineuronal net and synaptic loss in a CSF1R+/− mouse model of ALSP, which can be rescued via CSF1R inhibitors MA Arreola, N Soni, JD Crapser, LA Hohsfield, MRP Elmore, DP Matheos, ... Science advances 7 (35), eabg1601, 2021 | 38 | 2021 |
| Effects of long-term and brain-wide colonization of peripheral bone marrow-derived myeloid cells in the CNS LA Hohsfield, AR Najafi, Y Ghorbanian, N Soni, EE Hingco, SJ Kim, ... Journal of neuroinflammation 17, 1-20, 2020 | 37 | 2020 |
| β‐Amyloid induced effects on cholinergic, serotonergic, and dopaminergic neurons is differentially counteracted by anti‐inflammatory drugs T Hochstrasser, LA Hohsfield, B Sperner‐Unterweger, C Humpel Journal of neuroscience research 91 (1), 83-94, 2013 | 33 | 2013 |
| Homocysteine enhances transmigration of rat monocytes through a brain capillary endothelial cell monolayer via ICAM-1 L A Hohsfield, C Humpel Current neurovascular research 7 (3), 192-200, 2010 | 31 | 2010 |
| Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave LA Hohsfield, AR Najafi, Y Ghorbanian, N Soni, J Crapser, DXF Velez, ... Elife 10, e66738, 2021 | 28 | 2021 |
| Intravenous infusion of monocytes isolated from 2-week-old mice enhances clearance of Beta-amyloid plaques in an Alzheimer mouse model LA Hohsfield, C Humpel PLoS One 10 (4), e0121930, 2015 | 28 | 2015 |
| Aging and progression of beta-amyloid pathology in Alzheimer’s disease correlates with microglial heme-oxygenase-1 overexpression C Fernández-Mendívil, MA Arreola, LA Hohsfield, KN Green, MG Lopez Antioxidants 9 (7), 644, 2020 | 24 | 2020 |
| Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-human ACE2 transgenic mice GM Olivarria, Y Cheng, S Furman, C Pachow, LA Hohsfield, ... Journal of virology 96 (4), e01969-21, 2022 | 21 | 2022 |
| The generation of NGF-secreting primary rat monocytes: a comparison of different transfer methods LA Hohsfield, S Geley, M Reindl, C Humpel Journal of immunological methods 391 (1-2), 112-124, 2013 | 21 | 2013 |
| MAC2 is a long‐lasting marker of peripheral cell infiltrates into the mouse CNS after bone marrow transplantation and coronavirus infection LA Hohsfield, KI Tsourmas, Y Ghorbanian, AR Syage, S Jin Kim, Y Cheng, ... Glia 70 (5), 875-891, 2022 | 14 | 2022 |
| Intravenous infusion of nerve growth factor‐secreting monocytes supports the survival of cholinergic neurons in the nucleus basalis of meynert in hypercholesterolemia brown … LA Hohsfield, D Ehrlich, C Humpel Journal of neuroscience research 92 (3), 298-306, 2014 | 11 | 2014 |
| Cholesterol diet counteracts repeated anesthesia/infusion-induced cognitive deficits in male Brown Norway rats LA Hohsfield, D Ehrlich, C Humpel Neurobiology of learning and memory 106, 154-162, 2013 | 10 | 2013 |
