Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory and analgesic effects of the natural marine compound lemnalol from Formosan soft coral … YH Jean, WF Chen, CY Duh, SY Huang, CH Hsu, CS Lin, CS Sung, ... European journal of pharmacology 578 (2-3), 323-331, 2008 | 148 | 2008 |
Capnellene, a natural marine compound derived from soft coral, attenuates chronic constriction injury‐induced neuropathic pain in rats YH Jean, WF Chen, CS Sung, CY Duh, SY Huang, CS Lin, MH Tai, ... British journal of pharmacology 158 (3), 713-725, 2009 | 140 | 2009 |
Inhibition of the Ras/Raf interaction and repression of renal cancer xenografts in vivo by an enantiomeric iridium (III) metal-based compound LJ Liu, W Wang, SY Huang, Y Hong, G Li, S Lin, J Tian, Z Cai, HMD Wang, ... Chemical Science 8 (7), 4756-4763, 2017 | 120 | 2017 |
Glucosamine sulfate reduces experimental osteoarthritis and nociception in rats: association with changes of mitogen-activated protein kinase in chondrocytes ZH Wen, CC Tang, YC Chang, SY Huang, SP Hsieh, CH Lee, GS Huang, ... Osteoarthritis and Cartilage 18 (9), 1192-1202, 2010 | 116 | 2010 |
Effects of 6-Hydroxydopamine Exposure on Motor Activity and Biochemical Expression in Zebrafish (Danio Rerio) Larvae CW Feng, ZH Wen, SY Huang, HC Hung, CH Chen, SN Yang, NF Chen, ... Zebrafish 11 (3), 227-239, 2014 | 100 | 2014 |
Intra-articular magnesium sulfate (MgSO4) reduces experimental osteoarthritis and nociception: association with attenuation of N-methyl-D-aspartate (NMDA) receptor subunit 1 … CH Lee, ZH Wen, YC Chang, SY Huang, CC Tang, WF Chen, SP Hsieh, ... Osteoarthritis and cartilage 17 (11), 1485-1493, 2009 | 98 | 2009 |
The role of the PI3K/Akt/mTOR pathway in glial scar formation following spinal cord injury CH Chen, CS Sung, SY Huang, CW Feng, HC Hung, SN Yang, NF Chen, ... Experimental Neurology 278, 27-41, 2016 | 91 | 2016 |
Sinularin from indigenous soft coral attenuates nociceptive responses and spinal neuroinflammation in carrageenan-induced inflammatory rat model SY Huang, NF Chen, WF Chen, HC Hung, HP Lee, YY Lin, HM Wang, ... Marine drugs 10 (9), 1899-1919, 2012 | 74 | 2012 |
TGF-β1 attenuates spinal neuroinflammation and the excitatory amino acid system in rats with neuropathic pain NF Chen, SY Huang, WF Chen, CH Chen, CH Lu, CL Chen, SN Yang, ... The Journal of Pain 14 (12), 1671-1685, 2013 | 73 | 2013 |
Astaxanthin reduces MMP expressions, suppresses cancer cell migrations, and triggers apoptotic caspases of in vitro and in vivo models in melanoma YT Chen, CJ Kao, HY Huang, SY Huang, CY Chen, YS Lin, ZH Wen, ... Journal of Functional Foods 31, 20-31, 2017 | 62 | 2017 |
Neuroprotection by marine-derived compound, 11-dehydrosinulariolide, in an in vitro Parkinson’s model: A promising candidate for the treatment of Parkinson’s disease WF Chen, C Chakraborty, CS Sung, CW Feng, YH Jean, YY Lin, HC Hung, ... Naunyn-Schmiedeberg's archives of pharmacology 385, 265-275, 2012 | 61 | 2012 |
Interneuron origin and molecular diversity in the human fetal brain Y Yu, Z Zeng, D Xie, R Chen, Y Sha, S Huang, W Cai, W Chen, W Li, R Ke, ... Nature neuroscience 24 (12), 1745-1756, 2021 | 59 | 2021 |
Neuroprotective effect of the marine-derived compound 11-dehydrosinulariolide through DJ-1-related pathway in in vitro and in vivo models of Parkinson’s disease CW Feng, HC Hung, SY Huang, CH Chen, YR Chen, CY Chen, SN Yang, ... Marine Drugs 14 (10), 187, 2016 | 56 | 2016 |
Minocycline and fluorocitrate suppress spinal nociceptive signaling in intrathecal IL‐1β–induced thermal hyperalgesic rats CS Sung, CH Cherng, ZH Wen, WK Chang, SY Huang, SL Lin, KH Chan, ... Glia 60 (12), 2004-2017, 2012 | 55 | 2012 |
MSP-4, an antimicrobial peptide, induces apoptosis via activation of extrinsic Fas/FasL-and intrinsic mitochondria-mediated pathways in one osteosarcoma cell line HM Kuo, CC Tseng, NF Chen, MH Tai, HC Hung, CW Feng, SY Cheng, ... Marine drugs 16 (1), 8, 2018 | 53 | 2018 |
A novel zebrafish model to provide mechanistic insights into the inflammatory events in carrageenan-induced abdominal edema SY Huang, CW Feng, HC Hung, C Chakraborty, CH Chen, WF Chen, ... PLoS One 9 (8), e104414, 2014 | 52 | 2014 |
Extraction and characterization of phenolic compounds with antioxidant and antimicrobial activities from pickled radish J Li, SY Huang, Q Deng, G Li, G Su, J Liu, HMD Wang Food and Chemical Toxicology 136, 111050, 2020 | 51 | 2020 |
A Soft Coral-Derived Compound, 11-epi-Sinulariolide Acetate Suppresses Inflammatory Response and Bone Destruction in Adjuvant-Induced Arthritis YY Lin, YH Jean, HP Lee, WF Chen, YM Sun, JH Su, Y Lu, SY Huang, ... PloS one 8 (5), e62926, 2013 | 48 | 2013 |
Calcitonin attenuates cartilage degeneration and nociception in an experimental rat model of osteoarthritis: role of TGF-β in chondrocytes ZH Wen, CC Tang, YC Chang, SY Huang, YY Lin, SP Hsieh, HP Lee, ... Scientific reports 6 (1), 28862, 2016 | 44 | 2016 |
The use of the antimicrobial peptide piscidin (PCD)-1 as a novel anti-nociceptive agent WF Chen, SY Huang, CY Liao, CS Sung, JY Chen, ZH Wen Biomaterials 53, 1-11, 2015 | 44 | 2015 |