| Hepatocyte growth factor twenty years on: Much more than a growth factor T Nakamura, K Sakai, T Nakamura, K Matsumoto Journal of gastroenterology and hepatology 26, 188-202, 2011 | 578 | 2011 |
| Histamine H4 and H2 receptors control histamine-induced interleukin-16 release from human CD8+ T cells F Gantner, K Sakai, MW Tusche, WW Cruikshank, DM Center, KB Bacon Journal of Pharmacology and Experimental Therapeutics 303 (1), 300-307, 2002 | 243 | 2002 |
| Discovery of novel and selective IKK-β serine-threonine protein kinase inhibitors. Part 1 T Murata, M Shimada, S Sakakibara, T Yoshino, H Kadono, T Masuda, ... Bioorganic & medicinal chemistry letters 13 (5), 913-918, 2003 | 235 | 2003 |
| A selective novel low-molecular-weight inhibitor of IκB kinase-β (IKK-β) prevents pulmonary inflammation and shows broad anti-inflammatory activity K Ziegelbauer, F Gantner, NW Lukacs, A Berlin, K Fuchikami, T Niki, ... British journal of pharmacology 145 (2), 178, 2005 | 199 | 2005 |
| Critical role of histamine H4 receptor in leukotriene B4 production and mast cell-dependent neutrophil recruitment induced by zymosan in vivo K Takeshita, K Sakai, KB Bacon, F Gantner Journal of Pharmacology and Experimental Therapeutics 307 (3), 1072-1078, 2003 | 173 | 2003 |
| Non–small cell lung cancer cells acquire resistance to the ALK inhibitor alectinib by activating alternative receptor tyrosine kinases H Isozaki, E Ichihara, N Takigawa, K Ohashi, N Ochi, M Yasugi, ... Cancer research 76 (6), 1506-1516, 2016 | 138 | 2016 |
| Artificial human Met agonists based on macrocycle scaffolds K Ito, K Sakai, Y Suzuki, N Ozawa, T Hatta, T Natsume, K Matsumoto, ... Nature communications 6 (1), 6373, 2015 | 129 | 2015 |
| CD40‐dependent and‐independent activation of human tonsil B cells by CpG oligodeoxynucleotides F Gantner, P Hermann, K Nakashima, S Matsukawa, K Sakai, KB Bacon European journal of immunology 33 (6), 1576-1585, 2003 | 110 | 2003 |
| Hepatocyte growth factor and Met in tumor biology and therapeutic approach with NK4 K Matsumoto, T Nakamura, K Sakai, T Nakamura Proteomics 8 (16), 3360-3370, 2008 | 88 | 2008 |
| HGF–Met pathway in regeneration and drug discovery K Matsumoto, H Funakoshi, H Takahashi, K Sakai Biomedicines 2 (4), 275-300, 2014 | 86 | 2014 |
| Hepatocyte growth factor and Met in drug discovery K Sakai, S Aoki, K Matsumoto The journal of biochemistry 157 (5), 271-284, 2015 | 80 | 2015 |
| Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor K Sakai, T Passioura, H Sato, K Ito, H Furuhashi, M Umitsu, J Takagi, ... Nature chemical biology 15 (6), 598-606, 2019 | 69 | 2019 |
| Pleural mesothelioma instigates tumor-associated fibroblasts to promote progression via a malignant cytokine network Q Li, W Wang, T Yamada, K Matsumoto, K Sakai, Y Bando, H Uehara, ... The American journal of pathology 179 (3), 1483-1493, 2011 | 64 | 2011 |
| Inhibition of Met/HGF receptor and angiogenesis by NK4 leads to suppression of tumor growth and migration in malignant pleural mesothelioma Y Suzuki, K Sakai, J Ueki, Q Xu, T Nakamura, H Shimada, T Nakamura, ... International journal of cancer 127 (8), 1948-1957, 2010 | 60 | 2010 |
| α-Lipoic acid-induced inhibition of proliferation and met phosphorylation in human non-small cell lung cancer cells H Michikoshi, T Nakamura, K Sakai, Y Suzuki, E Adachi, S Matsugo, ... Cancer Letters 335 (2), 472-478, 2013 | 46 | 2013 |
| Anti-cancer approach with NK4: bivalent action and mechanisms T Nakamura, K Sakai, T Nakamura, K Matsumoto Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2010 | 45 | 2010 |
| Angioinhibitory action of NK4 involves impaired extracellular assembly of fibronectin mediated by perlecan-NK4 association K Sakai, T Nakamura, K Matsumoto, T Nakamura Journal of Biological Chemistry 284 (33), 22491-22499, 2009 | 43 | 2009 |
| Inhibition of transforming growth factor-β signaling potentiates tumor cell invasion into collagen matrix induced by fibroblast-derived hepatocyte growth factor J Oyanagi, N Kojima, H Sato, S Higashi, K Kikuchi, K Sakai, K Matsumoto, ... Experimental Cell Research 326 (2), 267-279, 2014 | 40 | 2014 |
| Lower gefitinib dose led to earlier resistance acquisition before emergence of T790M mutation in epidermal growth factor receptor‐mutated lung cancer model H Hayakawa, E Ichihara, K Ohashi, T Ninomiya, M Yasugi, S Takata, ... Cancer Science 104 (11), 1440-1446, 2013 | 36 | 2013 |
| Different growth and metastatic phenotypes associated with a cell-intrinsic change of Met in metastatic melanoma E Adachi, K Sakai, T Nishiuchi, R Imamura, H Sato, K Matsumoto Oncotarget 7 (43), 70779, 2016 | 33 | 2016 |
