| Bronchoalveolar lavage of murine lungs to analyze inflammatory cell infiltration L Van Hoecke, ER Job, X Saelens, K Roose JoVE (Journal of Visualized Experiments), e55398, 2017 | 160 | 2017 |
| How mRNA therapeutics are entering the monoclonal antibody field L Van Hoecke, K Roose Journal of translational medicine 17 (1), 1-14, 2019 | 150 | 2019 |
| Arginine‐rich peptide‐based mRNA nanocomplexes efficiently instigate cytotoxic t cell immunity dependent on the amphipathic organization of the peptide VK Udhayakumar, A De Beuckelaer, J McCaffrey, CM McCrudden, ... Advanced healthcare materials 6 (13), 1601412, 2017 | 148 | 2017 |
| Type I interferons interfere with the capacity of mRNA lipoplex vaccines to elicit cytolytic T cell responses A De Beuckelaer, C Pollard, S Van Lint, K Roose, L Van Hoecke, ... Molecular Therapy 24 (11), 2012-2020, 2016 | 123 | 2016 |
| Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes L Van Hoecke, S Van Lint, K Roose, A Van Parys, P Vandenabeele, ... Nature communications 9 (1), 1-17, 2018 | 113 | 2018 |
| Surfactant protein B (SP-B) enhances the cellular siRNA delivery of proteolipid coated nanogels for inhalation therapy P Merckx, L De Backer, L Van Hoecke, R Guagliardo, M Echaide, ... Acta biomaterialia 78, 236-246, 2018 | 67 | 2018 |
| mRNA in cancer immunotherapy: beyond a source of antigen L Van Hoecke, R Verbeke, H Dewitte, I Lentacker, K Vermaelen, ... Molecular Cancer 20 (1), 1-14, 2021 | 61 | 2021 |
| Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist L Nuhn, L Van Hoecke, K Deswarte, B Schepens, Y Li, BN Lambrecht, ... Biomaterials 178, 643-651, 2018 | 60 | 2018 |
| Intracellular Delivery of mRNA in Adherent and Suspension Cells by Vapor Nanobubble Photoporation L Raes, S Stremersch, JC Fraire, T Brans, G Goetgeluk, S De Munter, ... Nano-Micro Letters 12 (1), 1-17, 2020 | 57 | 2020 |
| Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12 S De Koker, L Van Hoecke, A De Beuckelaer, K Roose, K Deswarte, ... Scientific reports 7 (1), 1-14, 2017 | 41 | 2017 |
| The Opposing Effect of Type I IFN on the T Cell Response by Non-modified mRNA-Lipoplex Vaccines Is Determined by the Route of Administration L Van Hoecke, K Roose, M Ballegeer, Z Zhong, NN Sanders, S De Koker, ... Molecular Therapy-Nucleic Acids 22, 373-381, 2020 | 40 | 2020 |
| mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice L Van Hoecke, R Verbeke, D De Vlieger, H Dewitte, K Roose, ... Molecular Therapy-Nucleic Acids 20, 777-787, 2020 | 35 | 2020 |
| Mx1 in hematopoietic cells protects against Thogoto Virus infection J Spitaels, L Van Hoecke, K Roose, G Kochs, X Saelens Journal of virology 93 (15), 2019 | 26 | 2019 |
| Delivery of Mixed-Lineage Kinase Domain-Like Protein by Vapor Nanobubble Photoporation Induces Necroptotic-Like Cell Death in Tumor Cells L Van Hoecke, L Raes, S Stremersch, T Brans, JC Fraire, R Roelandt, ... International journal of molecular sciences 20 (17), 4254, 2019 | 26 | 2019 |
| Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice PT Joe, I Christopoulou, L Van Hoecke, B Schepens, T Ysenbaert, ... Journal of translational medicine 17 (1), 1-14, 2019 | 25 | 2019 |
| Coadministration of a plasmid encoding HIV-1 gag enhances the efficacy of Cancer DNA vaccines L Lambricht, K Vanvarenberg, A De Beuckelaer, L Van Hoecke, J Grooten, ... Molecular Therapy 24 (9), 1686-1696, 2016 | 25 | 2016 |
| Transiently thermoresponsive acetal polymers for safe and effective administration of amphotericin B as a vaccine adjuvant S Van Herck, L Van Hoecke, B Louage, L Lybaert, R De Coen, S Kasmi, ... Bioconjugate chemistry 29 (3), 748-760, 2017 | 23 | 2017 |
| Cholesterol‐sensing liver X receptors stimulate Th2‐driven allergic eosinophilic asthma in mice M Smet, L Van Hoecke, A De Beuckelaer, S Vander Beken, T Naessens, ... Immunity, inflammation and disease 4 (3), 350-361, 2016 | 23 | 2016 |
| GM-CSF treatment prevents respiratory syncytial virus–induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation T Naessens, B Schepens, M Smet, C Pollard, L Van Hoecke, ... Journal of Allergy and Clinical Immunology 137 (3), 700-709. e9, 2016 | 23 | 2016 |
| Recombinant viruses delivering the necroptosis mediator MLKL induce a potent antitumor immunity in mice L Van Hoecke, S Riederer, X Saelens, G Sutter, JJ Rojas Oncoimmunology 9 (1), 1802968, 2020 | 22 | 2020 |
