Towards a transgenic model of Huntington's disease in a non-human primate SH Yang, PH Cheng, H Banta, K Piotrowska-Nitsche, JJ Yang, EC Cheng, ... Nature 453 (7197), 921-4, 2008 | 576 | 2008 |
Transgenic monkeys produced by retroviral gene transfer into mature oocytes AW Chan, KY Chong, C Martinovich, C Simerly, G Schatten Science 291 (5502), 309-12, 2001 | 408 | 2001 |
Transgenic cattle produced by reverse-transcribed gene transfer in oocytes AWS Chan, EJ Homan, LB Ballou, JC Burns, RD Bremel Proc. Natl. Acad. Sci. USA 95 (24), 14028-33, 1998 | 312 | 1998 |
A small molecule enhances RNA interference and promotes microRNA processing G Shan, Y Li, J Zhang, W Li, KE Szulwach, R Duan, MA Faghihi, AM Khalil, ... Nat Biotechnol 26 (8), 933-40, 2008 | 287 | 2008 |
MagA is sufficient for producing magnetic nanoparticles in mammalian cells, making it an MRI reporter O Zurkiya, AW Chan, X Hu Magn Reson Med 59 (6), 1225-31, 2008 | 217 | 2008 |
Isolation and characterization of dental pulp stem cells from a supernumerary tooth AH Huang, YK Chen, LM Lin, TY Shieh, AW Chan J Oral Pathol Med 37 (9), 571-4, 2008 | 215 | 2008 |
Putative dental pulp-derived stem/stromal cells promote proliferation and differentiation of endogenous neural cells in the hippocampus of mice AH Huang, BR Snyder, PH Cheng, AW Chan Stem Cells 26 (10), 2654-63, 2008 | 205 | 2008 |
Clonal propagation of primate offspring by embryo splitting AW Chan, T Dominko, CM Luetjens, E Neuber, C Martinovich, L Hewitson, ... Science 287 (5451), 317-9, 2000 | 178 | 2000 |
Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease CE Wang, S Tydlacka, AL Orr, SH Yang, RK Graham, MR Hayden, S Li, ... Hum Mol Genet 17 (17), 2738-51, 2008 | 165 | 2008 |
Foreign DNA transmission by ICSI: injection of spermatozoa bound with exogenous DNA results in embryonic GFP expression and live rhesus monkey births AW Chan, CM Luetjens, T Dominko, J Ramalho-Santos, CR Simerly, ... Mol Hum Reprod 6 (1), 26-33, 2000 | 157 | 2000 |
SNAREs in mammalian sperm: possible implications for fertilization. J Ramalho-Santos, RD Moreno, P Sutovsky, AW Chan, L Hewitson, ... Dev Biol 223 (1), 54-69, 2000 | 148 | 2000 |
Transgenic pigs produced using in vitro matured oocytes infected with a retroviral vector RA Cabot, B Kühholzer, AW Chan, L Lai, KW Park, KY Chong, G Schatten, ... Anim biotechnol 12 (2), 205-14, 2001 | 137 | 2001 |
Dynamic imaging of the metaphase II spindle and maternal chromosomesin bovine oocytes: implications for enucleation efficiency verification, avoidanceof parthenogenesis, and … T Dominko, A Chan, C Simerly, CM Luetjens, L Hewitson, C Martinovich, ... Biol Reprod 62 (1), 150-4, 2000 | 128 | 2000 |
miR-196a ameliorates phenotypes of Huntington disease in cell, transgenic mouse, and induced pluripotent stem cell models PH Cheng, CL Li, YF Chang, SJ Tsai, YY Lai, AW Chan, CM Chen, ... Am J Hum Genet 93 (2), 306-12, 2013 | 117 | 2013 |
Methods for creating transgenic animals RD Bremel, AWS Chan, JC Burns US Patent 6,080,912, 2000 | 105 | 2000 |
Human multipotent stromal cells (MSCs) increase neurogenesis and decrease atrophy of the striatum in a transgenic mouse model for Huntington's disease BR Snyder, AM Chiu, DJ Prockop, AW Chan PLoS One 5 (2), 9347, 2010 | 104 | 2010 |
Isolation and characterization of human dental pulp stem/stromal cells from nonextracted crown-fractured teeth requiring root canal therapy AH Huang, YK Chen, AW Chan, TY Shieh, LM Lin J Endod 35 (5), 673-81, 2009 | 100 | 2009 |
Noninvasive monitoring of embryonic stem cells in vivo with MRI transgene reporter J Liu, EC Cheng, RC Long, SH Yang, L Wang, PH Cheng, J Yang, D Wu, ... Tissue Eng Part C Methods 15 (4), 739-47, 2009 | 93 | 2009 |
microRNA-128a dysregulation in transgenic Huntington's disease monkeys J Kocerha, Y Xu, MS Prucha, D Zhao, AW Chan Mol Brain 7, 46, 2014 | 92 | 2014 |
Progress and prospects for genetic modification of nonhuman primate models in biomedical research AWS Chan ilar Journal 54 (2), 211-223, 2013 | 90 | 2013 |