Consistent success in life-supporting porcine cardiac xenotransplantation M Längin, T Mayr, B Reichart, S Michel, S Buchholz, S Guethoff, ... Nature 564 (7736), 430-433, 2018 | 457 | 2018 |
Intravenous immunoglobulins–understanding properties and mechanisms A Durandy, SV Kaveri, TW Kuijpers, M Basta, S Miescher, JV Ravetch, ... Clinical & Experimental Immunology 158 (Supplement_1), 2-13, 2009 | 290 | 2009 |
Isotype‐specific detection of ABO blood group antibodies using a novel flow cytometric method G Stussi, K Huggel, HU Lutz, U Schanz, R Rieben, JD Seebach British journal of haematology 130 (6), 954-963, 2005 | 192 | 2005 |
Immunoglobulin M–enriched human intravenous immunoglobulin prevents complement activation in vitro and in vivo in a rat model of acute inflammation R Rieben, A Roos, Y Muizert, C Tinguely, AF Gerritsen, MR Daha Blood, The Journal of the American Society of Hematology 93 (3), 942-951, 1999 | 191 | 1999 |
A single localized dose of enzyme-responsive hydrogel improves long-term survival of a vascularized composite allograft T Gajanayake, R Olariu, FM Leclère, A Dhayani, Z Yang, AK Bongoni, ... Science translational medicine 6 (249), 249ra110-249ra110, 2014 | 169 | 2014 |
C1-inhibitor in patients with severe sepsis and septic shock: beneficial effect on renal dysfunction C Caliezi, S Zeerleder, M Redondo, B Regli, HU Rothen, ... Critical care medicine 30 (8), 1722-1728, 2002 | 132 | 2002 |
Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1α and dendritic cell maturation under normoxic conditions R Spirig, S Djafarzadeh, T Regueira, SG Shaw, C von Garnier, J Takala, ... PloS one 5 (6), e10983, 2010 | 110 | 2010 |
Lack of galactose-α-1, 3-galactose expression on porcine endothelial cells prevents complement-induced lysis but not direct xenogeneic NK cytotoxicity BC Baumann, P Forte, RJ Hawley, R Rieben, MKJ Schneider, ... The Journal of Immunology 172 (10), 6460-6467, 2004 | 108 | 2004 |
Antibodies to histo‐blood group substances A and B: agglutination titers, Ig class, and IgG subclasses in healthy persons of different age categories R Rieben, JP Bbuchs, E Flückiger, UE Nydegger Transfusion 31 (7), 607-615, 1991 | 103 | 1991 |
Preservation of amputated extremities by extracorporeal blood perfusion; a feasibility study in a porcine model MA Constantinescu, E Knall, X Xu, DM Kiermeir, H Jenni, E Gygax, ... Journal of Surgical Research 171 (1), 291-299, 2011 | 97 | 2011 |
Viable pigs after simultaneous inactivation of porcine MHC class I and three xenoreactive antigen genes GGTA1, CMAH and B4GALNT2 K Fischer, B Rieblinger, R Hein, R Sfriso, J Zuber, A Fischer, B Klinger, ... Xenotransplantation 27 (1), e12560, 2020 | 96 | 2020 |
Role of complement and perspectives for intervention in ischemia-reperfusion damage Y Banz, R Rieben Annals of Medicine 44 (3), 205-217, 2012 | 96 | 2012 |
Detection, immunoabsorption, and inhibition of cytotoxic activity of anti‐αGal antibodies using newly developed substances with synthetic Gal α1–3Gal disaccharide epitopes R Rieben, E von Allmen, EY Korchagina, UE Nydegger, FA Neethling, ... Xenotransplantation 2 (2), 98-106, 1995 | 93 | 1995 |
Xenograft rejection: IgG1, complement and NK cells team up to activate and destroy the endothelium R Rieben, JD Seebach Trends in immunology 26 (1), 2-5, 2005 | 91 | 2005 |
Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single-and multitransgenic pigs A Wuensch, A Baehr, AK Bongoni, E Kemter, A Blutke, W Baars, S Haertle, ... Transplantation 97 (2), 138-147, 2014 | 86 | 2014 |
Impact of porcine cytomegalovirus on long-term orthotopic cardiac xenotransplant survival J Denner, M Längin, B Reichart, L Krüger, U Fiebig, M Mokelke, J Radan, ... Scientific reports 10 (1), 17531, 2020 | 84 | 2020 |
Reactivity of human natural antibodies to endothelial cells from Galα (1, 3) Gal-deficient pigs BC Baumann, G Stussi, K Huggel, R Rieben, JD Seebach Transplantation 83 (2), 193-201, 2007 | 83 | 2007 |
Quantitation and characterization of anti‐Galα1–3Gal antibodies in sera of 200 healthy persons R Buonomano, C Tinguely, R Rieben, PJ Mohacsi, UE Nydegger Xenotransplantation 6 (3), 173-180, 1999 | 79 | 1999 |
Successful management of an ABO-mismatched lung allograft using antigen-specific immunoadsorption, complement inhibition, and immunomodulatory therapy1 RN Pierson III, JE Loyd, A Goodwin, D Majors, JS Dummer, P Mohacsi, ... Transplantation 74 (1), 79-84, 2002 | 77 | 2002 |
Ischemia/reperfusion injury: effect of simultaneous inhibition of plasma cascade systems versus specific complement inhibition C Duehrkop, R Rieben Biochemical pharmacology 88 (1), 12-22, 2014 | 76 | 2014 |