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Kanchan Garai
Kanchan Garai
Tata Institute of Fundamental Research Hyderabad
在 tifrh.res.in 的电子邮件经过验证 - 首页
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ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions
PB Verghese, JM Castellano, K Garai, Y Wang, H Jiang, A Shah, G Bu, ...
Proceedings of the National Academy of Sciences 110 (19), E1807-E1816, 2013
6312013
Measuring size distribution in highly heterogeneous systems with fluorescence correlation spectroscopy
P Sengupta, K Garai, J Balaji, N Periasamy, S Maiti
Biophysical journal 84 (3), 1977-1984, 2003
2492003
Unmasking the roles of N-and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation
SL Crick, KM Ruff, K Garai, C Frieden, RV Pappu
Proceedings of the National Academy of Sciences 110 (50), 20075-20080, 2013
2312013
The amyloid β peptide (Aβ1-40) is thermodynamically soluble at physiological concentrations
P Sengupta, K Garai, B Sahoo, Y Shi, DJE Callaway, S Maiti
Biochemistry 42 (35), 10506-10513, 2003
1982003
Quantitative analysis of the time course of Aβ oligomerization and subsequent growth steps using tetramethylrhodamine-labeled Aβ
K Garai, C Frieden
Proceedings of the National Academy of Sciences 110 (9), 3321-3326, 2013
1502013
Structural differences between apoE3 and apoE4 may be useful in developing therapeutic agents for Alzheimer’s disease
C Frieden, K Garai
Proceedings of the National Academy of Sciences 109 (23), 8913-8918, 2012
1452012
Zinc lowers amyloid-β toxicity by selectively precipitating aggregation intermediates
K Garai, B Sahoo, SK Kaushalya, R Desai, S Maiti
Biochemistry 46 (37), 10655-10663, 2007
1342007
The binding of apolipoprotein E to oligomers and fibrils of amyloid-β alters the kinetics of amyloid aggregation
K Garai, PB Verghese, B Baban, DM Holtzman, C Frieden
Biochemistry 53 (40), 6323-6331, 2014
1332014
Selective destabilization of soluble amyloid β oligomers by divalent metal ions
K Garai, P Sengupta, B Sahoo, S Maiti
Biochemical and biophysical research communications 345 (1), 210-215, 2006
1272006
Quantitative assessments of the distinct contributions of polypeptide backbone amides versus side chain groups to chain expansion via chemical denaturation
AS Holehouse, K Garai, N Lyle, A Vitalis, RV Pappu
Journal of the American Chemical Society 137 (8), 2984-2995, 2015
1122015
Hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry determine the interface and dynamics of apolipoprotein E oligomerization
RYC Huang, K Garai, C Frieden, ML Gross
Biochemistry 50 (43), 9273-9282, 2011
992011
Lipopolysaccharide from gut microbiota modulates α-synuclein aggregation and alters its biological function
D Bhattacharyya, GM Mohite, J Krishnamoorthy, N Gayen, S Mehra, ...
ACS chemical neuroscience 10 (5), 2229-2236, 2019
872019
Mass spectrometry-based protein footprinting characterizes the structures of oligomeric apolipoprotein E2, E3, and E4
B Gau, K Garai, C Frieden, ML Gross
Biochemistry 50 (38), 8117-8126, 2011
742011
The association− dissociation behavior of the ApoE proteins: Kinetic and equilibrium studies
K Garai, C Frieden
Biochemistry 49 (44), 9533-9541, 2010
662010
Dissociation of apolipoprotein E oligomers to monomer is required for high-affinity binding to phospholipid vesicles
K Garai, B Baban, C Frieden
Biochemistry 50 (13), 2550-2558, 2011
622011
Quasihomogeneous nucleation of amyloid beta yields numerical bounds for the critical radius, the surface tension, and the free energy barrier for nucleus formation
K Garai, B Sahoo, P Sengupta, S Maiti
The Journal of Chemical Physics 128 (4), 2008
602008
Detecting amyloid-β aggregation with fiber-based fluorescence correlation spectroscopy
K Garai, R Sureka, S Maiti
Biophysical journal 92 (7), L55-L57, 2007
522007
Probing transient non-native states in amyloid beta fiber elongation by NMR
JR Brender, A Ghosh, SA Kotler, J Krishnamoorthy, S Bera, V Morris, ...
Chemical Communications 55 (31), 4483-4486, 2019
512019
Concerning the structure of apoE
C Frieden, K Garai
Protein Science 22 (12), 1820-1825, 2013
482013
Expression and purification of amyloid-β peptides from Escherichia coli
K Garai, SL Crick, SM Mustafi, C Frieden
Protein expression and purification 66 (1), 107-112, 2009
472009
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