Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits SW Min, X Chen, TE Tracy, Y Li, Y Zhou, C Wang, K Shirakawa, ... Nature medicine 21 (10), 1154, 2015 | 486 | 2015 |
Scalable production of iPSC-derived human neurons to identify tau-lowering compounds by high-content screening C Wang, ME Ward, R Chen, K Liu, TE Tracy, X Chen, M Xie, PD Sohn, ... Stem cell reports 9 (4), 1221-1233, 2017 | 282 | 2017 |
Transcription Factor–Mediated Differentiation of Human iPSCs into Neurons MS Fernandopulle, R Prestil, C Grunseich, C Wang, L Gan, ME Ward Current Protocols in Cell Biology 79 (1), e51, 2018 | 269 | 2018 |
Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models SS Minami, SW Min, G Krabbe, C Wang, Y Zhou, R Asgarov, Y Li, ... Nature medicine 20 (10), 1157, 2014 | 253 | 2014 |
Quantitative profiling of endogenous retinoic acid in vivo and in vitro by tandem mass spectrometry MA Kane, AE Folias, C Wang, JL Napoli Analytical chemistry 80 (5), 1702-1708, 2008 | 249 | 2008 |
Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss TE Tracy, PD Sohn, SS Minami, C Wang, SW Min, Y Li, Y Zhou, D Le, I Lo, ... Neuron 90 (2), 245-260, 2016 | 233 | 2016 |
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes M Song, X Yang, X Ren, L Maliskova, B Li, IR Jones, C Wang, F Jacob, ... Nature genetics 51 (8), 1252, 2019 | 167 | 2019 |
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy C Wang, L Fan, RR Khawaja, B Liu, L Zhan, L Kodama, M Chin, Y Li, D Le, ... Nature communications 13 (1), 1969, 2022 | 146 | 2022 |
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration TE Tracy, J Madero-Pérez, DL Swaney, TS Chang, M Moritz, C Konrad, ... Cell 185 (4), 712-728. e14, 2022 | 142 | 2022 |
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain L Zhan, G Krabbe, F Du, I Jones, MC Reichert, M Telpoukhovskaia, ... PLoS biology 17 (2), e3000134, 2019 | 140 | 2019 |
Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases LG Chao Wang, Maria A Telpoukhovskaia, Ben A Bahr, Xu Chen Current Opinion in Neurobiology, 52-58, 2017 | 137* | 2017 |
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice nature communications, 2021 | 128 | 2021 |
Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein C Wang, B Sun, Y Zhou, A Grubb, L Gan Journal of Biological Chemistry 287 (47), 39834-39841, 2012 | 127 | 2012 |
Poly (ADP-ribose) polymerase-1 modulates microglial responses to amyloid β TM Kauppinen, SW Suh, Y Higashi, AE Berman, C Escartin, SJ Won, ... Journal of neuroinflammation 8 (1), 152, 2011 | 112 | 2011 |
Reducing acetylated tau is neuroprotective in brain injury MK Shin, E Vázquez-Rosa, Y Koh, M Dhar, K Chaubey, CJ Cintrón-Pérez, ... Cell, 2021 | 110 | 2021 |
Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation LT Grinberg, X Wang, C Wang, PD Sohn, P Theofilas, M Sidhu, ... Acta neuropathologica 125 (4), 581-593, 2013 | 108 | 2013 |
Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes R Krencik, K Seo, JV van Asperen, N Basu, C Cvetkovic, S Barlas, ... Stem Cell Reports 9 (6), 1745-1753, 2017 | 99 | 2017 |
Ethanol elevates physiological all-trans-retinoic acid levels in select loci through altering retinoid metabolism in multiple loci: a potential mechanism of ethanol toxicity MA Kane, AE Folias, C Wang, JL Napoli The FASEB Journal 24 (3), 823-832, 2010 | 93 | 2010 |
Multiple retinol and retinal dehydrogenases catalyze all-trans-retinoic acid biosynthesis in astrocytes C Wang, MA Kane, JL Napoli Journal of Biological Chemistry 286 (8), 6542-6553, 2011 | 80 | 2011 |
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy X Chen, Y Li, C Wang, Y Tang, SA Mok, RM Tsai, JC Rojas, A Karydas, ... Molecular Neurodegeneration 15 (1), 1-19, 2020 | 76 | 2020 |